Le Gravettien des Pyrénées

International audienceThe authors present an overview about the Gravettian in the Pyrenees. The geographical area held for this study was divided into three main zones : the Iberian Basque country, the Atlantic and Central Pyrenees, the Eastern Pyrenees. The synthesis proposed is built around the four following topics : - the history of researches and chronostratigraphic context; - material culture: lithic and bone industries; - artistic and symbolic evidences : body ornamentation, mobiliary art and rock art; - palaeo-environment.Les auteurs présentent un panorama général sur le Gravettien des Pyrénées. L'espace géographique retenu pour cette étude a été découpé en trois zones principales : le Pays Basque ibérique, les Pyrénées atlantiques et centrales, les Pyrénées orientales. La synthèse proposée se structure autour des quatre thèmes suivants : - histoire des recherches et contexte chrono-stratigraphique ; - culture matérielle : industrie lithique et osseuse ; - témoignages artistiques et symboliques : parure, art mobilier et art pariétal ; - le paléo-environnement

XXVII International Congress of Psychology, Estocolmo, 2000

Contiene los resúmenes de: Coping with stress : different approaches / Dra. María Cristina Richaud de Minzi ; Interpersonal trust in coping with stress / Dra. Carla Sacchi ; Development of coping resources in childhood and adolescence / Dra. María Cristina Richaud de Minzi ; Vocational choice as a source of stress / Nuria Cortada de Kohan ; Gender and coping style in old age / Lic. Dorina Stefan

Le Gravettien des Pyrénées

Les auteurs présentent un panorama général sur le Gravettien des Pyrénées. L’espace géographique retenu pour cette étude a été découpé en trois zones principales : le Pays Basque ibérique, les Pyrénées atlantiques et centrales, les Pyrénées orientales. La synthèse proposée se structure autour des quatre thèmes suivants :- histoire des recherches et contexte chrono-stratigraphique ;- culture matérielle : industrie lithique et osseuse ;- témoignages artistiques et symboliques : parure, art mobilier et art pariétal ;- le paléo-environnement.The authors present an overview about the Gravettian in the Pyrenees. The geographical area held for this study was divided into three main zones: the Iberian Basque country, the Atlantic and Central Pyrenees, the Eastern Pyrenees. The synthesis proposed is built around the four following topics: - the history of researches and chronostratigraphic context;- material culture: lithic and bone industries;- artistic and symbolic evidences: body ornamentation, mobiliary art and rock art;- palaeo-environment

Phenylalanine Butyramide Is a New Cosmetic Ingredient with Soothing and Anti-Reddening Potential

Human skin is colonized by diverse commensal microbes, making up the skin microbiota (SM), contributing to skin integrity and homeostasis. Many of the beneficial effects aroused by the SM are exerted by microbial metabolites such as short-chain fatty acids (SCFAs), including butyric acid. The SCFAs can be used in cosmetic formulations against skin diseases to protect SM by preserving and/or restoring their natural balance. Unpleasant sensorial properties and unfavorable physicochemical properties of butyrate strongly limit its cosmetic use. In contrast, some butyrate derivatives, including phenylalanine butyramide (C13H18N2O2 , FBA), a solid form of butyric acid, are odorless while retaining the pharmacokinetic properties and safety profile of butyric acid. This study assessed the FBA’s permeation across the skin and its soothing and anti-reddening potential to estimate its cosmetic application. The dosage method used to estimate FBA’s levels was validated to be sure of analytical results. The FBA diffusion tests were estimated in vitro using a Franz-type vertical diffusion cell. The soothing action was evaluated in vivo by Colorimeter CL400, measuring the erythema index. The results suggest that the FBA represents an innovative way to exploit the benefits of butyric acid in the cosmetic fields since it cannot reach the bloodstream, is odorless, and has a significative soothing action (decrease the erythema index −15.7% after 300 , and −17.8% after 600 )

Lack of efficacy of convalescent plasma in COVID-19 patients with concomitant hematological malignancies: An Italian retrospective study

A multicenter retrospective study was designed to assess clinical outcome of COVID-19 in patients with hematological malignancies (HM) following treatment with anti-SARS-CoV-2 convalescent plasma (CP) or standard of care therapy. To this aim, a propensity score matching was used to assess the role of non-randomized administration of CP in this high-risk cohort of patients from the Italian Hematology Alliance on COVID-19 (ITA-HEMA-COV) project, now including 2049 untreated control patients. We investigated 30- and 90-day mortality, rate of admission to intensive care unit, proportion of patients requiring mechanical ventilatory support, hospitalization time, and SARS-CoV-2 clearance in 79 CP recipients and compared results with 158 propensity score-matched controls. Results indicated a lack of efficacy of CP in the study group compared with the untreated group, thus confirming the negative results obtained from randomized studies in immunocompetent individuals with COVID-19. In conclusion, this retrospective analysis did not meet the primary and secondary end points in any category of immunocompromized patients affected by HM

Importation and early local transmission of COVID-19 in Brazil, 2020

We conducted the genome sequencing and analysis of the first confirmed COVID-19 infections in Brazil. Rapid sequencing coupled with phylogenetic analyses in the context of travel history corroborate multiple independent importations from Italy and local spread during the initial stage of COVID-19 transmission in Brazil