186 research outputs found
Recent advances of graphene-based hybrids with magnetic nanoparticles for biomedical applications
The utilization of graphene-based nanomaterials combined with magnetic nanoparticles offers key benefits in the modern biomedicine. In this minireview, we focus on the most recent advances in hybrids of magnetic graphene derivatives for biomedical applications. We initially analyze the several methodologies employed for the preparation of graphene-based composites with magnetic nanoparticles, more specifically the kind of linkage between the two components. In the last section, we focus on the biomedical applications where these magnetic-graphene hybrids are essential and pay special attention on how the addition of graphene improves the resulting devices in magnetic resonance imaging, controlled drug delivery, magnetic photothermal therapy and cellular separation and isolation. Finally, we highlight the use of these magnetic hybrids as multifunctional material that will lead to a next generation of theranostics
The Covalent Functionalization of Graphene on Substrates
The utilization of grown or deposited graphene on solid substrates offers key benefits for functionalization processes, but especially to attain structures with a high level of control for electronics and \u201csmart\u201d materials. In this review, we will initially focus on the nature and properties of graphene on substrates, based on the method of preparation. We will then analyze the most relevant literature on the functionalization of graphene on substrates. In particular, we will comparatively discuss radical reactions, cycloadditions, halogenations, hydrogenations, and oxidations. We will especially address the question of how the reactivity of graphene is affected by its morphology (i.e., number of layers, defects, substrate, curvature, etc.)
Management of tourist routes for Málaga
Ante la gran cantidad de turistas que cada año vienen a visitar la ciudad de Málaga y la gran cantidad de ofertas de elementos turÃsticos que nuestra ciudad ofrece, surge la necesidad de desarrollar una aplicación web (con un diseño responsive) en la que a través de una serie de elementos turÃsticos que previamente están definidos en el sistema, el usuario pueda organizar una ruta, en la que entre otros aspectos, se pueden seleccionar cuales de estos lugares les gustarÃa visitar, indicar el horario que tendrá disponible para realizar la ruta, asà como el dÃa de la semana y el lugar de partida.
A través de estas preferencias elegidas por el usuario, el sistema se encargará de planificar una ruta donde se indicará entre otros aspectos:
- Los elementos que son posible visitar atendiendo el horario y dÃa elegido.
- El orden en el que se deben de realizar las visitas.
- El tiempo que se debe emplear en cada visita, el cual coincide con el tiempo medio que un usuario suele tardar en completar la visita de las instalaciones.
- Rutas gráficas y paneles de indicaciones que mostrarán los pasos a seguir para ir desde un lugar turÃstico a otro
Transitando identidades. La mediación artÃstica en el proceso de rehabilitación de personas con problemas de adicciones
During 2010 y 2011, two volunteers, students from the Faculty of Fine Arts from the University of Barcelona, have developed a project in a support center for people with addiction problems. This center is Centre d’Atenció i Seguiment (CAS) in Sants district from Barcelona. In this article we present the theoretical framework and the experiences in order to substantiate how artistic experience contributes to the process of social reintegration of these individuals.Durante los años 2010 y 2011, dos voluntarios, estudiantes de la Facultad de Bellas Artes de la Universidad de Barcelona, han desarrollado un proyecto en el Centre d’Atenció i Seguiment a personas con problemas de adicciones (CAS) del barrio barcelonés de Sants. Presentamos el marco teórico y las experiencias con el objetivo de corroborar cómo la experiencia artÃstica contribuye al proceso de reinserción social de estos sujetos
Structure of 4-(~-D-Erythrofuranosyl)-3-methyl- l-(p-tolyl)-4-imidazoline-2-thione Monohydrate, C 15H18N203S.H20
Mr=324.4, orthorhombic, P212t2 ~, a=
32.150(5), b=10.215(1), c=4.805(1)A, V=
1578.0 (4)/~3, Z = 4, D x = 1.36 Mg m -a, 2(Cu Ka) =
1.5418A, #=1.953mm -1, T=300K, final R=
0.050 for 1361 observed [I>2tr(I)] independent
reflexions. The sugar ring adopts a conformation
intermediate between envelope 2E and twist 2T forms.
The orientation of the imidazoline ring with respect to
the furanose is anti; the glycosidic angle is 24.6 (7) °.
The crystal packing is due to hydrogen bonds involving
the hydration water molecules
Lattice-Dynamical Calculation of Second-Order Thermal Diffuse Scattering in Molecular Crystals
A computer procedure has been developed to calculate
second-order thermal diffuse scattering (TDS)
intensity for molecular crystals from latticedynamical
calculations with an atom-atom potential
in the Born-von K~irmfin formalism. It is applied to
monoclinic phenothiazine and different contributions
to second-order TDS intensity, acoustic-acoustic,
acoustic-optic and optic-optic, are compared. Calculations
are also performed in the long-wave approximation
allowing for dispersion (LWD) and correction
factors of Bragg intensities due to TDS contribution
in the LWD approximation are, generally but not
always, lower than lattice-dynamical ones; the ratio
between LWD and 'exact' factors ranges from 0.4 to
1.4 for reflections considered
Structure of 1,3-Dihydro-4-[(2R)-2,5-dihydro-2-furyl]-3-phenyl-l-(p-tolyl)-2H-imidazole- 2-thione, C20HlsN2OS
Mr=334.4, orthorhombic, P212~2 ~, a=
9.366(4), b=20.616(5), c=9.137(4)A, V=
1764 (1) A 3, Z = 4, D x = 1.26 Mg m -3, 2(Mo Ka) =
0.7107 A, g = 0.18 mm -~, F(000) = 704, T= 300 K,
final R--0.056 (wR =0.052) for 1979 observed
reflections [I > 2a(/)]. The furanose ring is approximately
planar because of the double bond, 1.289 (9) A,
which affects the conformation of the ring. The dihedral
angle between the furanose and imidazole least-squares
planes is 69.9 (2) °. A possible C--H...O hydrogen
bond has been detected involving C and O atoms in the
furanose ring, giving infinite helical chains along [001 ]
First- and Second-Order Thermal Diffuse Scattering (TDS) Intensity in Molecular Crystals: Influence on Crystal Structure Parameters
First- and second-order thermal diffuse scattering
(TDS) intensities are calculated in the long-wave
approximation allowing for dispersion (LWD) in
monoclinic phenothiazine from polarization vectors
and lattice-mode frequencies obtained from lattice
dynamical calculations within the harmonic approximation
and the external Born-von K~irmfin formalism
using an atom-atom potential function in the form
V(r) =-A/r6+ B exp (-Cr). The influence of firstand
second-order TDS intensity on electronic density
maps is analysed and compared. Least-squares refinements
of positional and thermal parameters are
carried out in different ranges of sin 0/A taking into
account both first- and second-order TDS contributions
and the results are discussed
Lattice Dynamical Calculation of First-Order Thermal Diffuse Scattering in Phenothiazine
A computer program has been developed to calculate
first-order thermal diffuse scattering (TDS) intensity
from eigenvectors and eigenvalues of the dynamical
matrix obtained within the harmonic approximation
with an atom-atom potential function and the external
Born-yon Kfirmfin formalism. It is applied to
monoclinic phenothiazine and correction factors of
Bragg intensities due to TDS contribution are calculated
and compared with the long-wave approximation.
A Fourier difference synthesis is performed in
order to reveal the influence of TDS contributions
in electron density maps. A least-squares process is
carried out to obtain the changes in structural parameters
due to TDS contribution
Lattice Dynamics and Thermal Crystallographic Parameters in Phenothiazine
A computer program has been developed to study
the lattice dynamics of molecular crystals in the harmonic
approximation with the external Born-yon
KS.rm~n formalism and an atom-atom potential function.
Dispersion curves are obtained for monoclinic
phenothiazine together with frequency distribution
functions and external mode contribution to thermodynamic
functions. Lattice dynamical T, L and S
rigid-body tensors are obtained and individual thermal
tensors are compared with experiment. The disagreement
with respect to experimental results is of
the same order as the disagreement with a
Schomaker-Trueblood fit of experimental data
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