Moonlighters: A Product of Deprivation or Aspiration?

Le double emploi (ou le fait de recevoir un revenu supplémentaire à côté d'un emploi principal) est communément reconnu comme un phénomène courant. Cependant, ses effets sur la santé, le bien-être et l'efficacité au travail des employés n'ont jamais été réellement approfondis. Certains travaux ont déjà suggéré que le double emploi était source de tension auprès des employés et de compromis quant à leur engagement au travail et leur fonction. D'autres discussions ont considéré ce phénomène comme la source de satisfaction légitime et bénéfique que ne peut fournir le travail principal. En réalité, de nombreuses compagnies dépendent de la disponibilité du double emploi provenant d'autres firmes et cela sans se soucier des résultats.Les résultats obtenus ici le furent à travers une enquête effectuée auprès d'employés manuels de six firmes industrielles en utilisant un questionnaire qu'ils devaient compléter. Les employés faisant double emploi furent automatiquement identifiés par le biais d'une question concernant les revenus additionnels.Le taux de double emploi qui s'est dégagé de l'étude fut de 15% soit trois fois supérieur à celui rapporté dans les statistiques gouvernementales. Les comparaisons entre tenants et non-tenants de double emploi ne révèlent aucune différence significative quant au besoin d'accomplissement sur le lieu du travail principal ou à l'extérieur, sur la santé mentale, la performance au travail, l'absentéisme ou la possible mobilité d'emploi. Des différences significatives se dégagent seulement quant à l'activité sociale volontaire et des préférences concernant des prévisions de travail plus flexibles, dans les deux cas favorisant ceux qui ont un double emploi.Les résultats démontrent le peu d'inquiétude au niveau de la direction des compagnies quant aux conséquences néfastes du travail à l'extérieur. Les raisons possibles à cela incluent la sélection naturelle des niveaux d'engagements extérieurs sans graves conséquences et le développement de la part des tenants de double emploi d'expériences supplémentaires les aidant à mieux s'organiser et à sauver temps et énergie. Les implications relatives à des études futures dans d'autres types d'organisation, de couches démographiques différentes sont également prises en considération.This study explores the nature of relationships between moonlighting and several dependent variables, such as need fulfillment in work and non-work, mental health, participation in voluntary organizations, job performance, absenteeism, anticipated turnover and flex-time and short work week preferences

Potassium ferrate [Fe(VI)] does not mediate self-sterilization of a surrogate mars soil

BACKGROUND: Martian soil is thought to be enriched with strong oxidants such as peroxides and/or iron in high oxidation states that might destroy biological materials. There is also a high flux of ultraviolet radiation at the surface of Mars. Thus, Mars may be inhospitable to life as we know it on Earth. We examined the hypothesis that if the soil of Mars contains ferrates [Fe(VI)], the strongest of the proposed oxidizing species, and also is exposed to high fluxes of UV radiation, it will be self-sterilizing. RESULTS: Under ambient conditions (25°C, oxygen and water present) K(2)FeO(4 )mixed into sand mineralized some reactive organic molecules to CO(2), while less reactive compounds were not degraded. Dried endospores of Bacillus subtilis incubated in a Mars surrogate soil comprised of dry silica sand containing 20% by weight K(2)FeO(4 )and under conditions similar to those now on Mars (extreme desiccation, cold, and a CO(2)-dominated atmosphere) were resistant to killing by the ferrate-enriched sand. Similar results were observed with permanganate. Spores in oxidant-enriched sand exposed to high fluxes of UV light were protected from the sporocidal activity of the radiation below about 5 mm depths. CONCLUSION: Based on our data and previously published descriptions of ancient but dormant life forms on Earth, we suggest that if entities resembling bacterial endospores were produced at some point by life forms on Mars, they might still be present and viable, given appropriate germination conditions. Endospores delivered to Mars on spacecraft would possibly survive and potentially compromise life detection experiments

Using a microwave oven to determine moisture in forages (1993)

Harvesting and storing forage crops at the proper moisture is necessary to minimize forage losses and to maintain maximum nutritional value. But it is difficult to determine the moisture concentration of forage crops prior to ensiling or baling. This publication will discuss the method of using a microwave oven to determine moisture in forages.Barry Steevens, Ron Belyea, Richard Crawford (Department of Animal Sciences)Reviewed October 1993 -- Extension website

Individual Differences in Dopamine Are Associated with Reward Discounting in Clinical Groups But Not in Healthy Adults.

Some people are more willing to make immediate, risky, or costly reward-focused choices than others, which has been hypothesized to be associated with individual differences in dopamine (DA) function. In two studies using PET imaging, one empirical (Study 1: N = 144 males and females across 3 samples) and one meta-analytic (Study 2: N = 307 across 12 samples), we sought to characterize associations between individual differences in DA and time, probability, and physical effort discounting in human adults. Study 1 demonstrated that individual differences in DA D2-like receptors were not associated with time or probability discounting of monetary rewards in healthy humans, and associations with physical effort discounting were inconsistent across adults of different ages. Meta-analytic results for temporal discounting corroborated our empirical finding for minimal effect of DA measures on discounting in healthy individuals but suggested that associations between individual differences in DA and reward discounting depend on clinical features. Addictions were characterized by negative correlations between DA and discounting, but other clinical conditions, such as Parkinson's disease, obesity, and attention-deficit/hyperactivity disorder, were characterized by positive correlations between DA and discounting. Together, the results suggest that trait differences in discounting in healthy adults do not appear to be strongly associated with individual differences in D2-like receptors. The difference in meta-analytic correlation effects between healthy controls and individuals with psychopathology suggests that individual difference findings related to DA and reward discounting in clinical samples may not be reliably generalized to healthy controls, and vice versa.SIGNIFICANCE STATEMENT Decisions to forgo large rewards for smaller ones due to increasing time delays, uncertainty, or physical effort have been linked to differences in dopamine (DA) function, which is disrupted in some forms of psychopathology. It remains unclear whether alterations in DA function associated with psychopathology also extend to explaining associations between DA function and decision making in healthy individuals. We show that individual differences in DA D2 receptor availability are not consistently related to monetary discounting of time, probability, or physical effort in healthy individuals across a broad age range. By contrast, we suggest that psychopathology accounts for observed inconsistencies in the relationship between measures of DA function and reward discounting behavior

Metagenomic profiling : microarray analysis of an environmental genomic library

Genomic libraries derived from environmental DNA (metagenomic libraries) are useful for characterizing uncultured microorganisms. However, conventional library-screening techniques permit characterization of relatively few environmental clones. Here we describe a novel approach for characterization of a metagenomic library by hybridizing the library with DNA from a set of groundwater isolates, reference strains, and communities. A cosmid library derived from a microcosm of groundwater microorganisms was used to construct a microarray (COSMO) containing ~1-kb PCR products amplified from the inserts of 672 cosmids plus a set of 16S ribosomal DNA controls. COSMO was hybridized with Cy5-labeled genomic DNA from each bacterial strain, and the results were compared with the results for a common Cy3-labeled reference DNA sample consisting of a composite of genomic DNA from multiple species. The accuracy of the results was confirmed by the preferential hybridization of each strain to its corresponding rDNA probe. Cosmid clones were identified that hybridized specifically to each of 10 microcosm isolates, and other clones produced positive results with multiple related species, which is indicative of conserved genes. Many clones did not hybridize to any microcosm isolate; however, some of these clones hybridized to community genomic DNA, suggesting that they were derived from microbes that we failed to isolate in pure culture. Based on identification of genes by end sequencing of 17 such clones, DNA could be assigned to functions that have potential ecological importance, including hydrogen oxidation, nitrate reduction, and transposition. Metagenomic profiling offers an effective approach for rapidly characterizing many clones and identifying the clones corresponding to unidentified species of microorganisms

Aquilegia, Vol. 25 No. 4, May-June 2001: Newsletter of the Colorado Native Plant Society

https://epublications.regis.edu/aquilegia/1185/thumbnail.jp

Glaucoma in primates: cytochrome oxidase reactivity in parvo- and magnocellular

PURPOSE. To evaluate the differential effects of ganglion cell depletion from experimental glaucoma on the relative metabolic activities of neurons in the parvo (P)-and magno (M)-cellular visual pathways of the macaque visual system. METHODS. Monocular experimental glaucoma was induced in monkeys (Macaca mulatta and M. fascicularis) by applying a laser to the trabecular meshwork to increase intraocular pressure (IOP). After other behavioral and electrophysiological studies, the lateral geniculate nuclei (LGNs) and the primary visual cortices were analyzed for functional afference from surviving ganglion cells, indicated by cytochrome oxidase (CO) histochemistry. RESULTS. CO reactivity (COR) indicated a general reduction in neural metabolism with increasing severity of glaucoma. COR in the LGNs was reduced to the same degree in both the P-and M-cellular layers. In layer 4C␤ of the V1 cortex, the reactivity was always reduced more than in the layer 4C␣ division. CONCLUSIONS. Experimental glaucoma in monkeys reduces visual afference to the central nervous system, thereby reducing the metabolic drive as indicated by COR. The detrimental effect of glaucoma did not appear to be any greater for the M-cell, rather than the P-cell pathway in the LGN or in the visual cortex. Both are affected by the duration and severity of the experimental glaucoma. Overall, the alterations in metabolism of neurons in the parallel visual pathways supplied by the P␣ and P␤ ganglion cells do not suggest that tests based on the functional properties of one or the other would provide optimal assessment of glaucoma. (Invest Ophthalmol Vis Sci. 2000;41: 1791-180

Evaluation of menogaril in renal cell carcinoma

The Southwest Oncology Group (SWOG) studied the response rate and toxicity of menogaril (200 mg/m 2 i.v. q 28 days) in patients with advanced metastatic renal cell carcinoma. During the early stage of the trial two partial responses were seen in the first 20 treated patients, and an additional 36 evaluable patients were studied. Three of 56 (5%) evaluable patients achieved partial responses. Significant white cell toxicity was observed. Mild or moderate degrees of thrombocytopenia, gastrointestinal side effects, alopecia and phlebitis occurred. No cardiac toxicity was noted. The low response rate suggests that menogaril in this dose schedule has no role in the treatment of patients with advanced metastatic renal cancer.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45344/1/10637_2004_Article_BF00171987.pd

Phase II evaluation of piroxantrone in renal cell carcinoma

The Southwest Oncology Group (SWOG) studied the response rate and toxicity of piroxantrone (150 mg/m 2 q 21 days) in patients with advanced metastatic renal cell carcinoma. Among 32 eligible patients, there were no partial nor complete responses. There were two mixed responses. Significant white cell toxicity, anemia, nausea, and vomiting were observed. Mild or moderate degrees of fever, malaise, and stomatitis occurred. No significant cardiac toxicity was noted. Piroxantrone does not have significant activity as a single agent in advanced renal cell carcinoma.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45142/1/10637_2004_Article_BF00873131.pd

Diversity of oxygenase genes from Methane- and Ammonia-oxidizing bacteria in the Eastern Snake River Plain aquifier

PCR amplification, restriction fragment length polymorphism, and phylogenetic analysis of oxygenase genes were used for the characterization of in situ methane- and ammonia-oxidizing bacteria from free-living and attached communities in the Eastern Snake River Plain aquifer. The following three methane monooxygenase (MMO) PCR primer sets were used: A189-A682, which amplifies an internal region of both the pmoA gene of the MMO particulate form and the amoA gene of ammonia monooxygenase; A189-mb661, which specifically targets the pmoA gene; and mmoXA-mmoXB, which amplifies the mmoX gene of the MMO soluble form (sMMO). Whole-genome amplification (WGA) was used to amplify metagenomic DNA from each community to assess its applicability for generating unbiased metagenomic template DNA. The majority of sequences in each archive were related to oxygenases of type II-like methanotrophs of the genus Methylocystis. A small subset of type I sequences found only in free-living communities possessed oxygenase genes that grouped nearest to Methylobacter and Methylomonas spp. Sequences similar to that of the amoA gene associated with ammoniaoxidizing bacteria (AOB) most closely matched a sequence from the uncultured bacterium BS870 but showed no substantial alignment to known cultured AOB. Based on these functional gene analyses, bacteria related to the type II methanotroph Methylocystis sp. were found to dominate both free-living and attached communities. Metagenomic DNA amplified by WGA showed characteristics similar to those of unamplified samples. Overall, numerous sMMO-like gene sequences that have been previously associated with high rates of trichloroethylene cometabolism were observed in both free-living and attached communities in this basaltic aquifer.Copyrighted by American Society for Microbiology