567 research outputs found

    Quantum tomography for Dirac spinors

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    We present a tomographic scheme, based on spacetime symmetries, for the reconstruction of the internal degrees of freedom of a Dirac spinor. We discuss the circumstances under which the tomographic group can be taken as SU(2), and how this crucially depends on the choice of the gamma matrix representation. A tomographic reconstruction process based on discrete rotations is considered, as well as a continuous alternative.Comment: 9 pages, LaTeX; v2: minor changes, references added. A slightly revised version has been accepted for publication in Phys. Lett.

    Multipole Amplitudes of Pion Photoproduction on Nucleons up to 2GeV within Dispersion Relations and Unitary Isobar Model

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    Two approaches for analysis of pion photo- and electroproduction on nucleons in the resonance energy region are checked at Q2=0Q^2=0 using the results of GWU(VPI) partial-wave analysis of photoproduction data. The approaches are based on dispersion relations and unitary isobar model. Within dispersion relations good description of photoproduction multipoles is obtained up to W=1.8GeVW=1.8 GeV. Within unitary isobar model, modified with increasing energy by incorporation of Regge poles, and with unified Breit-Wigner parametrization of resonance contributions, good description of photoproduction multipoles is obtained up to W=2GeVW=2 GeV.Comment: 23 pages, LaTe

    Nuclear magnetization distribution and hyperfine splitting in Bi82+^{82+} ion

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    Hyperfine splitting in Bi82+^{82+} and Pb81+^{81+} ions was calculated using continuum RPA approach with effective residual forces. To fix the parameters of the theory the nuclear magnetic dipole moments of two one- particle and two one-hole nuclei around 208^{208}Pb were calculated using the same approach. The contribution from velocity dependent two-body spin- orbit residual interaction was calculated explicitly. Additionally, the octupole moment of 209^{209}Bi and the hfs in muonic bismuth atom were calculated as well in the same approach. All the calculated observables, except the electronic hfs in 209^{209}Bi, are in good agreement with the data. We argue for more accurate measurement of the octupole moment and the muonic hfs for 209^{209}Bi.Comment: 11 pages, 5 figure

    A river model of space

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    Within the theory of general relativity gravitational phenomena are usually attributed to the curvature of four-dimensional spacetime. In this context we are often confronted with the question of how the concept of ordinary physical three-dimensional space fits into this picture. In this work we present a simple and intuitive model of space for both the Schwarzschild spacetime and the de Sitter spacetime in which physical space is defined as a specified set of freely moving reference particles. Using a combination of orthonormal basis fields and the usual formalism in a coordinate basis we calculate the physical velocity field of these reference particles. Thus we obtain a vivid description of space in which space behaves like a river flowing radially toward the singularity in the Schwarzschild spacetime and radially toward infinity in the de Sitter spacetime. We also consider the effect of the river of space upon light rays and material particles and show that the river model of space provides an intuitive explanation for the behavior of light and particles at and beyond the event horizons associated with these spacetimes.Comment: 22 pages, 5 figure

    An exploration of the effectiveness of artificial mini-magnetospheres as a potential solar storm shelter for long term human space missions

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    If mankind is to explore the solar system beyond the confines of our Earth and Moon the problem of radiation protection must be addressed. Galactic cosmic rays and highly variable energetic solar particles are an ever-present hazard in interplanetary space. Electric and/or magnetic fields have been suggested as deflection shields in the past, but these treated space as an empty vacuum. In fact it is not empty. Space contains a plasma known as the solar wind; a constant flow of protons and electrons coming from the Sun. In this paper we explore the effectiveness of a “mini-magnetosphere” acting as a radiation protection shield. We explicitly include the plasma physics necessary to account for the solar wind and its induced effects. We show that, by capturing/containing this plasma, we enhance the effectiveness of the shield. Further evidence to support our conclusions can be obtained from studying naturally occurring “mini-magnetospheres” on the Moon. These magnetic anomalies (related to “lunar swirls”) exhibit many of the effects seen in laboratory experiments and computer simulations. If shown to be feasible, this technology could become the gateway to manned exploration of interplanetary space

    Overlapping regions of Caf20 mediate its interactions with the mRNA-5′cap-binding protein eIF4E and with ribosomes

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    By interacting with the mRNA 5′ cap, the translation initiation factor eIF4E plays a critical role in selecting mRNAs for protein synthesis in eukaryotic cells. Caf20 is a member of the family of proteins found across eukaryotes termed 4E-BPs, which compete with eIF4G for interaction with eIF4E. Caf20 independently interacts with ribosomes. Thus, Caf20 modulates the mRNA selection process via poorly understood mechanisms. Here we performed unbiased mutagenesis across Caf20 to characterise which regions of Caf20 are important for interaction with eIF4E and with ribosomes. Caf20 binding to eIF4E is entirely dependent on a canonical motif shared with other 4E-BPs. However, binding to ribosomes is weakened by mutations throughout the protein, suggesting an extended binding interface that partially overlaps with the eIF4E-interaction region. By using chemical crosslinking, we identify a potential ribosome interaction region on the ribosome surface that spans both small and large subunits and is close to a known interaction site of eIF3. The function of ribosome binding by Caf20 remains unclear

    Reinforcement of poly-l-lactic acid electrospun membranes with strontium borosilicate bioactive glasses for bone tissue engineering

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    Herein, for the first time, we combined poly-l-lactic acid (PLLA) with a strontium borosilicate bioactive glass (BBG-Sr) using electrospinning to fabricate a composite bioactive PLLA membrane loaded with 10% (w/w) of BBG-Sr glass particles (PLLA-BBG-Sr). The composites were characterised by scanning electron microscopy (SEM) and microcomputer tomography (μ-CT), and the results showed that we successfully fabricated smooth and uniform fibres (1-3μm in width) with a homogeneous distribution of BBG-Sr microparticles (<45μm). Degradation studies (in phosphate buffered saline) demonstrated that the incorporation of BBG-Sr glass particles into the PLLA membranes increased their degradability and water uptake with a continuous release of cations. The addition of BBG-Sr glass particles enhanced the membrane's mechanical properties (69% higher Young modulus and 36% higher tensile strength). Furthermore, cellular in vitro evaluation using bone marrow-derived mesenchymal stem cells (BM-MSCs) demonstrated that PLLA-BBG-Sr membranes promoted the osteogenic differentiation of the cells as demonstrated by increased alkaline phosphatase activity and up-regulated osteogenic gene expression (Alpl, Sp7 and Bglap) in relation to PLLA alone. These results strongly suggest that the composite PLLA membranes reinforced with the BBG-Sr glass particles have potential as an effective biomaterial capable of promoting bone regeneration. STATEMENT OF SIGNIFICANCE: PLLA membranes were reinforced with 10% (w/w) of strontium-bioactive borosilicate glass microparticles, and their capacity to induce the osteogenic differentiation of bone marrow mesenchymal stem cells (BM-MSCs) was evaluated. These membranes presented an increased: degradability, water uptake, Young modulus and tensile strength. We also demonstrated that these membranes are non-cytotoxic and promote the attachment of BM-MSCs. The addition of the glass microparticles into the PLLA membranes promoted the increase of ALP activity (under osteogenic conditions), as well as the BM-MSCs osteogenic differentiation as shown by the upregulation of Alpl, Sp7 and Bglap gene expression. Overall, we demonstrated that the reinforcement of PLLA with glass microparticles results in a biomaterial with the appropriate properties for the regeneration of bone tissue

    Epidemiological situation of bovine brucellosis in the State of Bahia, Brazil

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    O trabalho consistiu em estratificar o Estado da Bahia em quatro regiões com características homogêneas (circuitos produtores) para que fossem amostradas aleatoriamente, em cada uma delas, 300 propriedades. Em cada propriedade foram escolhidas, de forma aleatória, 10 a 15 fêmeas bovinas adultas, das quais foi obtida uma amostra de sangue. No total, foram amostrados 10.816 animais, provenientes de 1.413 propriedades. O protocolo de testes utilizado foi o da triagem com o teste do antígeno acidificado tamponado (Rosa Bengala) e a confirmação dos positivos com o teste do 2-mercaptoetanol. O rebanho foi considerado positivo se pelo menos um animal reagiu às duas provas sorológicas. As prevalências de focos e a de fêmeas adultas soropositivas do Estado foram de 4,2% [3,1-5,3%] e 0,66% [0,41-0,93%], respectivamente. Para os circuitos produtores foram: circuito 1, 5,8% [3,6-8,7%] e 0,86% [0,41-1,3%]; circuito 2, 3,1% [1,5-5,6%] e 1,2% [0,25-2,1%]; circuito 3, 6,3% [4,0-9,3%] e 1,7% [0,66-2,7%]; e circuito 4, 0,60% [0,07-2,2%] e 0,07 [0,00-0,21%]. Para a análise de fatores de riscos associados à doença foi aplicado um questionário epidemiológico em cada propriedade visitada. Os fatores de risco (odds ratio, OR) associados à condição de foco foram: compra de reprodutores (OR= 2,27) e presença de áreas alagadiças (OR= 1,76). A vacinação de fêmeas de três até oito meses de idade foi um fator de proteção (OR= 0,53). ____________________________________________________________________________________________________________________ ABSTRACTA study to characterize the epidemiological situation of bovine brucellosis in the State of Bahia was carried out in 2004. The State was divided into four similar production regions, 300 herds were randomly sampled in each region, and 10 to 15 adult bovine females were sampled in each of these herds. A total of 10,816 serum samples from 1,413 herds were collected. The serum samples were screened for antibodies to Brucella spp. by the Rose-Bengal Test (RBT), and all RBT-positive sera were re-tested by the 2-mercaptoethanol test (2-ME) for confirmation. A herd was considered positive if at least one animal was positive on both RBT and 2-ME tests. The prevalence of infected herds and seropositive adult bovine females in Bahia State were: 4.2% [3.1-5.3%] and 0.66% [0.41-0.93%], respectively. In the production regions, prevalence of infected herds and animals were, respectively: region 1, 5.8% [3.6-8.7%] and 0.86% [0.41-1.3%]; region 2, 3.1% [1.5-5.6%] and 1.2% [0.25-2.1%]; region 3, 6.3% [4.0-9.3%] and 1.7% [0.66-2.7%]; and region 4, 0.60% [0.07-2.2%] and 0.07%[0.00-0.2%]. In each herd, an epidemiological questionnaire was applied. The risk factors (odds ratio, OR) associated with the presence of the infection were: purchase of breeding animals (OR = 2.27) and presence of flood areas (OR= 1.76). Vaccination of heifers from three to eight months of age was a protective factor (OR=0.53)

    Epidemiological situation of bovine brucellosis in the State of Rondônia, Brazil

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    Realizou-se um estudo para caracterizar a situação epidemiológica da doença no Estado de Rondônia. O Estado foi estratificado em três circuitos produtores. Em cada circuito produtor foram amostradas aleatoriamente cerca de 300 propriedades e, dentro dessas, foi escolhido, de forma aleatória, um número pré-estabelecido de animais, dos quais foi obtida uma amostra de sangue. No total, foram amostrados 9.717 animais, provenientes de 927 propriedades. Em cada propriedade amostrada foi aplicado um questionário epidemiológico para verificar o tipo de exploração e as práticas zootécnicas e sanitárias que poderiam estar associadas ao risco de infecção pela doença. O protocolo de testes utilizado foi o da triagem com o teste do antígeno acidificado tamponado e o reteste dos positivos com o teste do 2-mercaptoetanol. O rebanho foi considerado positivo, se pelo menos um animal foi reagente às duas provas sorológicas. As prevalências de focos e de animais infectados do Estado foram de 35,2% [32,1-38,4%] e 6,2% [4,9-7,6%], respectivamente. Os resultados para os circuitos pecuários foram: circuito 1, 41,9% [36,3-47,6%] e 8,3% [5,9-10,8%]; circuito 2, 31,7% [26,5-37,2%] e 5,9% [4,3-7,6%]; circuito 3, 31,9% [26,7-37,4%] e 4,6% [2,5-6,6%]. Os fatores de risco (odds ratio, OR) associados à condição de foco foram: histórico de aborto (OR= 1,42 [1,04-1,95]) e exploração de corte (OR= 1,75 [1,30-2,38]). ______________________________________________________________________________________________________________ ABSTRACTA study to characterize the brucellosis epidemiological situation in the State of Rondônia was carried out. The State was divided into three regions. Three hundred herds were randomly sampled in each region. A pre-established number of animals were sampled in each of these herds. From 927 herds and 9,717 serum samples were collected. In each herd, it was applied an epidemiological questionnaire regarding herd features and also husbandry and sanitary practices that could be associated with risk of infection. The serum samples were screened for antibodies to Brucella spp. by the Rose-Bengal Test (RBT), and all RBT-positive sera were re-tested by the 2-mercaptoethanol test (2-ME). The herd was considered positive if at least one animal was positive on both RBT and 2-ME tests. The prevalences of infected herds and animals in Rondônia State were 35.2% [32.1-38.4%] and 6.2% [4.9-7.6%], respectively. In the regions, the prevalences of infected herds and animals were, respectively: region 1, 41.9% [36.3-47.6%] and 8.3% [5.9-10.8%]; region 2, 31.7% [26.5-37.2%] and 5.9% [4.3-7.6%]; and region 3, 31.9% [26.7-37.4%] and 4.6% [2.5-6.6%]. The risk factors (odds ratio, OR) associated with the presence of the infection were: recent history of abortion (OR= 1.42 [1.04-1.95]) and beef herd (OR=1.75 [1.30-2.38])
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