Examining Post-Adoption Services: What Adoptive Families Need for Beneficial Outcomes

This research is about what post-adoption services exist, what sort of supports and services adoptive families need, and if there are any disparities. The researcher aimed to answer the multidimensional research question: What types of post-adoption issues do adoptive parents identify, how were these issues addressed, and what do they recommend to other adoptive parents? A qualitative research design with a narrative analysis was used to conduct the study. The Ecological Approach was used as the conceptual framework. The researcher found that both participants participated in foster to adopt, felt they did not receive the full extent of the supports and services they needed, however they did have some informal personal supports they accessed on their own. The main theme of the data suggested that social workers and other professionals do not have the specific knowledge base about the workings and challenges of adoption that is necessary in order to properly serve the adoptive family population. Further research and additional education is required to appropriately meet the needs of these families in future work

Examining Post-Adoption Services: What Adoptive Families Need for Beneficial Outcomes

This research is about what post-adoption services exist, what sort of supports and services adoptive families need, and if there are any disparities. The researcher aimed to answer the multidimensional research question: What types of post-adoption issues do adoptive parents identify, how were these issues addressed, and what do they recommend to other adoptive parents? A qualitative research design with a narrative analysis was used to conduct the study. The Ecological Approach was used as the conceptual framework. The researcher found that both participants participated in foster to adopt, felt they did not receive the full extent of the supports and services they needed, however they did have some informal personal supports they accessed on their own. The main theme of the data suggested that social workers and other professionals do not have the specific knowledge base about the workings and challenges of adoption that is necessary in order to properly serve the adoptive family population. Further research and additional education is required to appropriately meet the needs of these families in future work

FIRST Course Portfolio for BIOC205: Scientific Analysis and Technical Writing

BIOC205: Scientific Analysis and Technical Writing is a core course for the Department of Biochemistry at the University of Nebraska-Lincoln. This course is geared for second year (sophomore students) with minimal prerequisites and as a foundation for future classes. Challenges include 1) teaching the needed scientific background and elements of scientific analysis and writing to a broad cohort of students with diverse backgrounds and interests, 2) building student skills towards analysis of primary peer-reviewed scientific literature, 3) developing students as writers of scientific information for different audiences. This course used Genetic Engineering as a broad topic choice to capture students interests and provide a platform where students could select their main assignment topic (a scientific review article that they write using information from peer-reviewed sources) on something that interests them to improve student engagement. This portfolio outlines my design (first time teaching this course) in alignment with a core course taught five times per year by three different instructors and analysis of the success of structured assignments that build to a final comprehensive analysis. Data from this first cohort demonstrates that foundational assignments and step-wise feedback is effective at student learning and feedback from students supports a majority gaining confidence in their skills

Hematopoietic stem cells and betaherpesvirus latency

The human betaherpesviruses including human cytomegalovirus (HCMV), human herpesvirus (HHV)-6a and HHV-6b, and HHV-7 infect and establish latency in CD34+ hematopoietic stem and progenitor cells (HPCs). The diverse repertoire of HPCs in humans and the complex interactions between these viruses and host HPCs regulate the viral lifecycle, including latency. Precise manipulation of host and viral factors contribute to preferential maintenance of the viral genome, increased host cell survival, and specific manipulation of the cellular environment including suppression of neighboring cells and immune control. The dynamic control of these processes by the virus regulate inter- and intra-host signals critical to the establishment of chronic infection. Regulation occurs through direct viral protein interactions and cellular signaling, miRNA regulation, and viral mimics of cellular receptors and ligands, all leading to control of cell proliferation, survival, and differentiation. Hematopoietic stem cells have unique biological properties and the tandem control of virus and host make this a unique environment for chronic herpesvirus infection in the bone marrow. This review highlights the elegant complexities of the betaherpesvirus latency and HPC virus-host interactions

EPIC Team Meetings

EPIC Team Meetings EPIC represents: effective and empowering agendas and action plans, productive product notebooks, information drill down, and collaborative communication. During this seminar segment, sample items such as agendas, action plans, product notebooks, and drill down forms will be shared as well as explained how they are utilized in our team meetings to cover all areas of student supports and interventions. SWIS drill down behavior data and interventions; attendance reports and supports; academic progress and interventions for Tier 2, 3, and 4 students; problem solutions; and action development are major areas covered within our team meetings which will be shared during this seminar, Past experiences and growth challenges will be shared so that other teams can learn from our team in order to make their team meetings more EPIC in their own buildings. Learning Outcomes: Leadership teams will learn how to make their team meetings EPIC as described above. Leadership teams.will learn how to use effective forms and agendas for streamlining meetings in order to openly discuss effective interventions and supports which are data driven according to their school needs. Leadership teams will learn from a school’s past experiences and growth challenges in order to not make the same mistakes and build stronger team meetings which will mean more effective and specific targeted interventions and supports for student, teacher, and system needs within their school buildings

When and why do initially high attaining poor children fall behind?

In this paper, we examine the trajectories of initially higher- and lower-achieving children from lower and higher socio-economic status families from primary school through to university in England for the first time. We also explore what explains these trajectories. This enables us to provide new insights into when and why the performance of children with similar initial achievement diverges on the basis of their socio-economic background. Our results indicate that pupils from poor backgrounds who are higher achievers in primary school fall behind their better-off but lower achieving peers during secondary school. This suggests that secondary school may be a critical period to intervene to prevent poor children from falling behind their richer peers. Our analysis suggests that there is less divergence in performance between pupils from different socio-economic backgrounds who attend the same schools. This result is particularly strong for children with low initial achievement. While we remain cautious about the implications of these findings, they provide suggestive evidence that schools (or the sorting of pupils into schools) play an important role in explaining why the test scores of richer and poorer children diverge over time

Hematopoietic stem cells and retroviral infection

Retroviral induced malignancies serve as ideal models to help us better understand the molecular mechanisms associated with the initiation and progression of leukemogenesis. Numerous retroviruses including AEV, FLV, M-MuLV and HTLV-1 have the ability to infect hematopoietic stem and progenitor cells, resulting in the deregulation of normal hematopoiesis and the development of leukemia/lymphoma. Research over the last few decades has elucidated similarities between retroviral-induced leukemogenesis, initiated by deregulation of innate hematopoietic stem cell traits, and the cancer stem cell hypothesis. Ongoing research in some of these models may provide a better understanding of the processes of normal hematopoiesis and cancer stem cells. Research on retroviral induced leukemias and lymphomas may identify the molecular events which trigger the initial cellular transformation and subsequent maintenance of hematologic malignancies, including the generation of cancer stem cells. This review focuses on the role of retroviral infection in hematopoietic stem cells and the initiation, maintenance and progression of hematological malignancies

Analysis of Select Dietary Supplement Products Marketed to Support or Boost the Immune System

Importance: Cold, flu, and immunity dietary supplement product sales have skyrocketed since the start of the COVID-19 pandemic. Supporting or boosting the immune system has become an important reason for using dietary supplements, and many consumers are purchasing products through online platforms. Objectives: To examine whether select dietary supplement products advertised as supporting or boosting the immune system are accurately labeled according to the Supplement Facts label of listed ingredients and to qualitatively describe the product labels\u27 characteristics in terms of claims made. Design, Setting, and Participants: In this case series, 30 featured immune health dietary supplements were selected and purchased from Amazon.com in May 2021. Product analysis was performed using liquid chromatography-mass spectrometry. The list of ingredients detected through analysis for each product was compared with the ingredients on the product\u27s Supplement Facts label to determine whether the product\u27s label was accurate. Claims made on product labels were also evaluated by using the Operation Supplement Safety Scorecard\u27s set of questions to describe the labels\u27 characteristics. Results: A total of 30 select dietary supplement products were evaluated. Thirteen of the 30 products had accurate labels based on the product analysis. Of the 17 products with inaccurate labels, 13 had ingredients listed on the labels that were not detected through analysis, such that their labels were misbranded. Nine products had substances detected that were not claimed on the product labels, some of which may be considered adulterated. Five were misbranded and contained additional components not claimed on the label. No product had third-party certification seals present on the packaging. Ten of the 13 products with accurate labels received a score of 4 or more when applying the Operation Supplement Safety Scorecard, meaning the product was likely okay/less risky. Conclusions and Relevance: In this case series study, most of the products tested had inaccurate labels and claims that were inconsistent with requirements the US Food and Drug Administration has put forward for dietary supplements. Quality control measures seem to be insufficient for most of these select products, and claims made on labels may be misleading consumers who purchase products

Higher education, career opportunities, and intergenerational inequality

The UK government has expressed a desire to increase social mobility, with policies to help achieve this aim focused on reducing inequalities in educational attainment. This paper draws together established and new information about the contribution that higher education can make to social mobility using a life-course approach, considering differences by family background in terms of university attendance and achievement, as well as occupation and earnings following graduation. We find substantial socio-economic differences at each stage. Young people from poorer backgrounds are, on average, less likely to go to university than their richer peers. Even among the selected group who do go to university, they are less likely to attend the highest status institutions, less likely to graduate, and less likely to achieve the highest degree classes. These differences in degree outcomes contribute to the lower average earnings of graduates from poorer families, but earnings differentials go well beyond those driven purely by degree attainment or institution attended. The evidence strongly suggests that, even after taking these factors into account, graduates from affluent families are more likely to obtain a professional job and to see higher earnings growth in the labour market. We discuss the implications of these findings for the prospects of higher education as a route to greater social mobilit