Upper Body Kinetics has No Difference for Mound and Flat Ground Throwing

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Lower Body Kinematics Do Not Differ Between Flat Ground and Mound Baseball Throwing

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TSGL A Thread Safe Graphics Library for Visualizing Parallelism

AbstractMulticore processors are now the standard CPU architecture, and multithreaded parallel programs are needed to take full advantage of such CPUs. New tools are needed to help students learn how to design and build such parallel programs. In this paper, we present the thread-safe graphics library (TSGL), a new C++11 library that allows different threads to draw to a shared Canvas, which is updated in approximate real-time. Using TSGL, instructors and students can create visualizations that illustrate multithreaded behavior. We present three multithreaded applications that illustrate the use of TSGL to help students see and understand how an application is using parallelism to speed up its computation

New measurements of total ionizing dose in the lunar environment

[1] We report new measurements of solar minimum ionizing radiation dose at the Moon onboard the Lunar Reconnaissance Orbiter (LRO) from June 2009 through May 2010. The Cosmic Ray Telescope for the Effects of Radiation (CRaTER) instrument on LRO houses a compact and highly precise microdosimeter whose design allows measurements of dose rates below 1 micro-Rad per second in silicon achieved with minimal resources (20 g, ∼250 milliwatts, and ∼3 bits/second). We envision the use of such a small yet accurate dosimeter in many future spaceflight applications where volume, mass, and power are highly constrained. As this was the first operation of the microdosimeter in a space environment, the goal of this study is to verify its response by using simultaneous measurements of the galactic cosmic ray ionizing environment at LRO, at L1, and with other concurrent dosimeter measurements and model predictions. The microdosimeter measured the same short timescale modulations in the galactic cosmic rays as the other independent measurements, thus verifying its response to a known source of minimum-ionizing particles. The total dose for the LRO mission over the first 333 days was only 12.2 Rads behind ∼130 mils of aluminum because of the delayed rise of solar activity in solar cycle 24 and the corresponding lack of intense solar energetic particle events. The dose rate in a 50 km lunar orbit was about 30 percent lower than the interplanetary rate, as one would expect from lunar obstruction of the visible sky

The lensing properties of subhaloes in massive elliptical galaxies in sterile neutrino cosmologies

We use high-resolution hydrodynamical simulations run with the EAGLE model of galaxy formation to study the differences between the properties of - and subsequently the lensing signal from - subhaloes of massive elliptical galaxies at redshift 0.2, in Cold and Sterile Neutrino (SN) Dark Matter models. We focus on the two 7 keV SN models that bracket the range of matter power spectra compatible with resonantly produced SN as the source of the observed 3.5 keV line. We derive an accurate parametrization for the subhalo mass function in these two SN models relative to cold dark matter (CDM), as well as the subhalo spatial distribution, density profile, and projected number density and the dark matter fraction in subhaloes. We create mock lensing maps from the simulated haloes to study the differences in the lensing signal in the framework of subhalo detection. We find that subhalo convergence is well described by a lognormal distribution and that signal of subhaloes in the power spectrum is lower in SN models with respect to CDM, at a level of 10-80 per cent, depending on the scale. However, the scatter between different projections is large and might make the use of power spectrum studies on the typical scales of current lensing images very difficult. Moreover, in the framework of individual detections through gravitational imaging a sample of ≃30 lenses with an average sensitivity of Msub = 5 × 107 M☉ would be required to discriminate between CDM and the considered sterile neutrino models

Procalcitonin guided antibiotic therapy and hospitalization in patients with lower respiratory tract infections: a prospective, multicenter, randomized controlled trial

<p>Abstract</p> <p>Background:</p> <p>Lower respiratory tract infections like acute bronchitis, exacerbated chronic obstructive pulmonary disease and community-acquired pneumonia are often unnecessarily treated with antibiotics, mainly because of physicians' difficulties to distinguish viral from bacterial cause and to estimate disease-severity. The goal of this trial is to compare medical outcomes, use of antibiotics and hospital resources in a strategy based on enforced evidence-based guidelines versus procalcitonin guided antibiotic therapy in patients with lower respiratory tract infections.</p> <p>Methods and design:</p> <p>We describe a prospective randomized controlled non-inferiority trial with an open intervention. We aim to randomize over a fixed recruitment period of 18 months a minimal number of 1002 patients from 6 hospitals in Switzerland. Patients must be >18 years of age with a lower respiratory tract infections <28 days of duration. Patients with no informed consent, not fluent in German, a previous hospital stay within 14 days, severe immunosuppression or chronic infection, intravenous drug use or a terminal condition are excluded. Randomization to either guidelines-enforced management or procalcitonin-guided antibiotic therapy is stratified by centre and type of lower respiratory tract infections. During hospitalization, all patients are reassessed at days 3, 5, 7 and at the day of discharge. After 30 and 180 days, structured phone interviews by blinded medical students are conducted. Depending on the randomization allocation, initiation and discontinuation of antibiotics is encouraged or discouraged based on evidence-based guidelines or procalcitonin cut off ranges, respectively. The primary endpoint is the risk of combined disease-specific failure after 30 days. Secondary outcomes are antibiotic exposure, side effects from antibiotics, rate and duration of hospitalization, time to clinical stability, disease activity scores and cost effectiveness. The study hypothesis is that procalcitonin-guidance is non-inferior (i.e., at worst a 7.5% higher combined failure rate) to the management with enforced guidelines, but is associated with a reduced total antibiotic use and length of hospital stay.</p> <p>Discussion:</p> <p>Use of and prolonged exposure to antibiotics in lower respiratory tract infections is high. The proposed trial investigates whether procalcitonin-guidance may safely reduce antibiotic consumption along with reductions in hospitalization costs and antibiotic resistance. It will additionally generate insights for improved prognostic assessment of patients with lower respiratory tract infections.</p> <p>Trial registration:</p> <p>ISRCTN95122877</p