The assessment of the flow requirements for upstream migration of salmonids in some rivers of North West England

This is the assessment of the flow requirements for upstream migration of salmonids in some rivers of North West England produced by the North West Water Authority in 1985. This report focuses on the automatic fish counters operating on the resistivity principle used for several years in North West England. This report aims to investigate the flow requirements for upstream migration of salmon and migratory trout. The data obtained confirmed that during summer months most fish movement occurs in the higher range of the available flows, but the migration flow range varied from year to year, depending on prevailing river levels. Of the other environmental variables measured, only water temperature and incident light intensity appear to have any direct association with fish movement. Information on migration flow ranges were used in conjunction with computer simulations of the effects of abstraction proposals on historical flows to assess the implications of these proposals for migratory fish

Discovery of Two New Class II Methanol Maser Transitions in G345.01+1.79

We have used the Swedish ESO Submillimetre Telescope (SEST) to search for new class II methanol maser transitions towards the southern source G345.01+1.79. Over a period of 5 days we observed 11 known or predicted class II methanol maser transitions. Emission with the narrow line width and characteristic velocity of class II methanol masers (in this source) was detected in 8 of these transitions, two of which have not previously been reported as masers. The new class II methanol maser transitions are the 13(-3)-12(-4)E transition at 104.1 GHz and the 5(1)-4(2)E transition at 216.9 GHz. Both of these are from transition series for which there are no previous known class II methanol maser transitions. This takes the total number of known class II methanol maser series to 10, and the total number of transitions (or transition groups) to 18. The observed 104.1 GHz maser suggests the presence of two or more regions of masing gas with similar line of sight velocities, but quite different physical conditions. Although these newly discovered transitions are likely to be relatively rare, where they are observed combined studies using the Australia Telescope Compact Array and the Atacama Large Millimeter Array offer the prospect to be able to undertake multi-transition methanol maser studies with unprecedented detail.Comment: 8 pages, 3 figures, accepted for publication in ApJ Letter

A Search for Biomolecules in Sagittarius B2 (LMH) with the ATCA

We have used the Australia Telescope Compact Array to conduct a search for the simplest amino acid, glycine (conformers I and II), and the simple chiral molecule propylene oxide at 3-mm in the Sgr B2 LMH. We searched 15 portions of spectrum between 85 and 91 GHz, each of 64 MHz bandwidth, and detected 58 emission features and 21 absorption features, giving a line density of 75 emission lines and 25 absorption lines per GHz stronger than the 5 sigma level of 110 mJy. Of these, 19 are transitions previously detected in the interstellar medium, and we have made tentative assignments of a further 23 features to molecular transitions. However, as many of these involve molecules not previously detected in the ISM, these assignments cannot be regarded with confidence. Given the median line width of 6.5 km/s in Sgr B2 LMH, we find that the spectra have reached a level where there is line confusion, with about 1/5 of the band being covered with lines. Although we did not confidently detect either glycine or propylene oxide, we can set 3 sigma upper limits for most transitions searched. We also show that if glycine is present in the Sgr B2 LMH at the level of N = 4 x 10^{14} cm^{-2} found by Kuan et al. (2003) in their reported detection of glycine, it should have been easily detected with the ATCA synthesized beam size of 17.0 x 3.4 arcsec^{2}, if it were confined to the scale of the LMH continuum source (< 5 arcsec). This thus puts a strong upper limit on any small-scale glycine emission in Sgr B2, for both of conformers I and II.Comment: 12 pages, 2 figures, 5 tables, accepted by MNRA

A search for 85.5- and 86.6-GHz methanol maser emission

We have used the Australia Telescope National Facility Mopra 22m millimetre telescope to search for emission from the 85.5-GHz and 86.6-GHz transitions of methanol. The search was targeted towards 22 star formation regions which exhibit maser emission in the 107.0-GHz methanol transition, as well as in the 6.6-GHz transition characteristic of class II methanol maser sources. A total of 22 regions were searched at 85.5 GHz resulting in 5 detections, of which 1 appears to be a newly discovered maser. For the 86.6-GHz transition observations were made of 18 regions which yielded 2 detections, but no new maser sources. This search demonstrates that emission from the 85.5- and 86.6-GHz transitions is rare. Detection of maser emission from either of these transitions therefore indicates the presence of special conditions, different from those in the majority of methanol maser sources. We have observed temporal variability in the 86.6-GHz emission towards 345.010+1.792, which along with the very narrow line width, confirms that the emission is a maser in this source. We have combined our current observations with published data for the 6.6-, 12.1-, 85.5-, 86.6-, 107.0-, 108.8- and 156.6-GHz transitions for comparison with the maser model of Sobolev & Deguchi (1994). This has allowed us to estimate the likely ranges of dust temperature, gas density, and methanol column density, both for typical methanol maser sources and for those sources which also show 107.0-GHz emission.Comment: 11 pages, accepted for publication in MNRAS, Latex, mn2e.cl

Models of class II methanol masers based on improved molecular data

The class II masers of methanol are associated with the early stages of formation of high-mass stars. Modelling of these dense, dusty environments has demonstrated that pumping by infrared radiation can account for the observed masers. Collisions with other molecules in the ambient gas also play a significant role, but have not been well modelled in the past. Here we examine the effects on the maser models of newly available collision rate coefficients for methanol. The new collision data does not alter which transitions become masers in the models, but does influence their brightness and the conditions under which they switch on and off. At gas temperatures above 100 K the effects are broadly consistent with a reduction in the overall collision cross-section. This means, for example, that a slightly higher gas density than identified previously can account for most of the observed masers in W3(OH). We have also examined the effects of including more excited state energy levels in the models, and find that these play a significant role only at dust temperatures above 300 K. An updated list of class II methanol maser candidates is presented.Comment: 14 pages, 4 figures, Accepted for publication in MNRA

Class II methanol maser candidates

Model spectra are presented for Class II methanol masers under a variety of conditions. The model is that of Sobolev & Deguchi, which includes pumping through levels of the second and first torsionally excited states. All the currently identified Class II methanol masers appear as strong masers in one or more of the model regimes, and a number of new maser candidates are identified. © 1997 RAS

Multi-transition study and new detections of class II methanol masers

We have used the ATNF Mopra antenna and the SEST antenna to search in the directions of several class II methanol maser sources for emission from six methanol transitions in the frequency range 85-115 GHz. The transitions were selected from excitation studies as potential maser candidates. Methanol emission at one or more frequencies was detected from five of the maser sources, as well as from Orion KL. Although the lines are weak, we find evidence of maser origin for three new lines in G345.01+1.79, and possibly one new line in G9.62+0.20. The observations, together with published maser observations at other frequencies, are compared with methanol maser modelling for G345.01+1.79 and NGC6334F. We find that the majority of observations in both sources are consistent with a warm dust (175 K) pumping model at hydrogen density ~10^6 cm^-3 and methanol column density ~5 x 10^17 cm^-2. The substantial differences between the maser spectra in the two sources can be attributed to the geometry of the maser region.Comment: 13 pages, 6 figures, Accepted for publication in MNRA

Detection of 6.7 GHz methanol absorption towards hot corinos

Methanol masers at 6.7 GHz have been found exclusively towards high-mass star forming regions. Recently, some Class 0 protostars have been found to display conditions similar to what are found in hot cores that are associated with massive star formation. These hot corino sources have densities, gas temperatures, and methanol abundances that are adequate for exciting strong 6.7 GHz maser emission. This raises the question of whether 6.7 GHz methanol masers can be found in both hot corinos and massive star forming regions, and if not, whether thermal methanol emission can be detected. We searched for the 6.7 GHz methanol line towards five hot corino sources in the Perseus region using the Arecibo radio telescope. To constrain the excitation conditions of methanol, we observed thermal submillimeter lines of methanol in the NGC1333-IRAS 4 region with the APEX telescope. We did not detect 6.7 GHz emission in any of the sources, but found absorption against the cosmic microwave background in NGC1333-IRAS 4A and NGC1333-IRAS 4B. Using a large velocity gradient analysis, we modeled the excitation of methanol over a wide range of physical parameters, and verify that the 6.7 GHz line is indeed strongly anti-inverted for densities lower than 10^6 cm^-3. We used the submillimeter observations of methanol to verify the predictions of our model for IRAS 4A by comparison with other CH3OH transitions. Our results indicate that the methanol observations from the APEX and Arecibo telescopes are consistent with dense (n ~ 10^6 cm^-3), cold (T ~ 15-30 K) gas. The lack of maser emission in hot corinos and low-mass protostellar objects in general may be due to densities that are much higher than the quenching density in the region where the radiation field is conducive to maser pumping.Comment: Accepted by A&

A third trial oversight committee: Functions, benefits and issues

BACKGROUND/AIMS: Clinical trial oversight is central to the safety of participants and production of robust data. The United Kingdom Medical Research Council originally set out an oversight structure comprising three committees in 1998. The first committee, led by the trial team, is hands-on with trial conduct/operations (‘Trial Management Group’) and essential. The second committee (Data Monitoring Committee), usually completely independent of the trial, reviews accumulating trial evidence and is used by most later phase trials. The Independent Data Monitoring Committee makes recommendations to the third oversight committee. The third committee, (‘Trial Steering Committee’), facilitates in-depth interactions of independent and non-independent trial members and gives broader oversight (blinded to comparative analysis). We investigated the roles and functioning of the third oversight committee with multiple research methods. We reflect upon these findings to standardise the committee’s remit and operation and to potentially increase its usage. METHODS: We utilised findings from our recent published suite of research on the third oversight committee to inform guideline revision. In brief, we conducted a survey of 38 United Kingdom–registered Clinical Trials Units, reviewed a cohort of 264 published trials, observed 8 third oversight committee meetings and interviewed 52 trialists. We convened an expert panel to discuss third oversight committees. Subsequently, we interviewed nine patient/lay third committee members and eight committee Chairs. RESULTS: In the survey, most Clinical Trials Units required a third committee for all their trials (27/38, 71%) with independent members (ranging from 1 to 6). In the survey and interviews, the independence of the third committee was valued to make unbiased consideration of Independent Data Monitoring Committee recommendations and to advise on trial progress, protocol changes and recruitment issues in conjunction with the trial leadership. The third committee also advised funders and sponsors about trial continuation and represented patients and the public by including lay members. Of the cohort of 264 published trials, 144 reported a ‘steering’ committee (55%), but the independence of these members was not described so these may have been internal Trial Management Groups. Around two thirds of papers (60%) reported having an Independent Data Monitoring Committee and 26.9% neither a steering nor an Independent Data Monitoring Committee. However, before revising the third committee charter (Terms of Reference), greater standardisation is needed around defining member independence, composition, primacy of decision-making, interactions with other committees and the lifespan. CONCLUSION: A third oversight committee has benefits for trial oversight and conduct, and a revised charter will facilitate greater standardisation and wider adoption

A sensitive search for predicted methanol maser transitions with the Australia telescope compact array

We have used theAustralia Telescope Compact Array to search for a number of centimetrewavelengthmethanol transitions which are predicted to show weak maser emission towards star formation regions. Sensitive, high spatial, and spectral resolution observations towards four high-mass star formation regions which show emission in a large number of class II methanol maser transitions did not result in any detections. From these observations, we are able to place an upper limit of 1 300 K on the brightness temperature of any emission from the 31A+-31A-, 17-2-18-3 E (vt = 1), 124-133 A-, 124-133 A+, and 41A+-41A- transitions of methanol in these sources on angular scales of 2 arcsec. This upper limit is consistent with current models for class II methanol masers in high-mass star formation regions and better constraints than those provided here will likely require observations with next-generation radio telescopes. © Astronomical Society of Australia 2016