13 research outputs found
New insights into the genetic etiology of Alzheimer's disease and related dementias
- Author
- Aaltonen L.
- Aaltonen V.
- Aarsland Dag
- Aavikko M.
- Abalos M.S.
- Abdelnour Carla
- Abner E.
- Abraham R.
- Adams H.
- Adams P.M.
- Adarmes-Gómez A.
- Adarmes-Gómez A.D.
- Aguilera N.
- Aguilera N.
- Aguirre A.
- Ahmad S.
- Akinyemi R.O.
- Al-Chalabi A.
- Alarcón-Martín Emilio
- Albert M.S.
- Albin R.L.
- Alcolea Daniel
- Alegret Montserrat
- Ali M.
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- Allende I.R.
- Alonso M.D.
- Alonso M.D.
- Alvarez I.
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- Sachdev Perminder S.
- Saenz A.
- Sager M.A.
- Sakka P.
- Sala G.
- Salmi T.
- Salminen A.
- Salo T.
- Salomaa V.
- Saltvedt I.
- Salvadori N.
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- Sastre I.
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- Schmidt H.
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- Schneider A.
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- Seitsonen S.
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- Selnes P.
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- Shcherban A.
- Shin J.
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- Siirtola H.
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- Sliz E.
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- Smith J.
- Smith J.P.
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- Solomon A.
- Song Y.E.
- Song Y.E.
- Sonnen J.A.
- Sorbi S.
- Sotolongo Grau Oscar
- Spallazzi M.
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- Spina S.
- Spottke A.
- Squassina A.
- Stern R.A.
- Stevens A.B.
- Stordal E.
- Strandberg T.
- Strauss E.
- Strittmatter S.M.
- Ståhlbom A.K.
- Sultzer D.
- Suominen L.
- Sussams R.
- Swerdlow R.H.
- Sáez María Eugenia
- Sánchez-Arjona M.B.
- Sánchez-Valle R.
- Takalo M.
- Tanzi R.E.
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- Tasanen K.
- Taskinen M.R.
- Teipel S.
- Teng E.
- Tesí N.
- Teumer A.
- Thalamuthu A.
- Thomas A.
- Thomas C.
- Thomas T.
- Thomassen J.Q.
- Thonberg H.
- Tienari P.
- Tilson J.L.
- Tin A.
- Todd S.
- Toso C.R.
- Tosto G.
- Traykov L.
- Tremolizzo L.
- Trojanowski J.Q.
- Troncoso J.C.
- Tsai E.
- Tsolaki A.
- Tsolaki M.
- Tsuang D.W.
- Tsuo K.
- Tucker-Drob E.
- Tukiainen T.
- Tuomi T.
- Tuomilehto J.
- Tuovila O.
- Turpeinen M.
- Turton J.
- Turunen J.A.
- Tybjærg-Hansen A.
- Tzourio C.
- Tárraga L.
- Uitterlinden A.
- Ullgren A.
- Ulstein I.
- Universitat Autònoma de Barcelona
- Uphill J.
- Usiskin K.
- Uusitalo H.
- Uusitalo-Järvinen H.
- Vacca A.
- Vainio S.
- Valero S.
- Valladares O.
- Valladares O.
- van Adelsberg J.
- Van Deerlin V.M.
- van den Bussche H.
- van der Flier Wiesje M
- van der Lee S.J.
- van der Lugt A.
- van Duijn C.M.
- van Eldik L.J.
- van Lent D.M.
- van Rooij J.
- van Swieten J.
- Vance J.
- Vandenberghe R.
- Vardarajan B.N.
- Vardy E.
- Vargas L.
- Vassar R.
- Verhey F.
- Vicente M. P.
- Vidal J.S.
- Vigo-Ortega R.
- Vigo-Ortega R.
- Vilas R.H.
- Vinters H.V.
- Virolainen P.
- Vivancos L.
- Vogelgsang J.
- Vojinovic D.
- Vonsattel J.P.
- Voutilainen M.
- Vyhnalek M.
- Wadhawan S.
- Wagner M.
- Wallon D.
- Wang C.
- Wang L.S.
- Wang R.
- Wang Y.
- Warden D.
- Waring J.
- Waring J.
- Warner N.
- Warren J.D.
- Waterworth D.
- Weber H.
- Weinhold L.
- Weinstein G.
- Weintraub S.
- Welsh-Bohmer K.A.
- Whelan C.
- Whitehead P.L.
- Wichmann H.E.
- Wigmore E.
- Wijsman E.M.
- Wilcock G.
- Wilhelmsen K.C.
- Williams A.
- Williams B.
- Williams D.
- Williams J.
- Williamson J.
- Wilms H.
- Wiltfang J.
- Windle G.
- Wingo T.S.
- Wisniewski T.
- Wittfeld K.
- Woltjer R.L.
- Wong R.
- Woods B.
- Woon M.
- Wright C.B.
- Wu C.K.
- Wu Y.
- Xia T.h.
- Xu E.
- Xu F.
- Yanek L.
- Yang Q.
- Yang Y.
- Yannakoulia M.
- Yaqub A.
- Younkin S.G.
- Yu C.E.
- Yu L.
- Zare H.
- Zhang X.
- Zhang Y.
- Zhao Y.
- Zhao Y.
- Zhou W.
- Zhu C.
- Zhu X.
- Ziemann A.
- Zoia C.P.
- Zompo M.D.
- Zulaica M.
- Álvarez V.
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele
Alterações metabólicas e funcionais do cobre em diabetes mellitus
- Author
- ARAI K.
- BALEVSKA P.S.
- BENSON G.D.
- BODE A.M.
- BREMNER J.
- BRIGGS J.
- BUCHMAN A.L.
- CAR N.
- CARLTON W.W.
- CARVILLE D.G.M.
- CHANG. K.
- CHEN Y.
- COHEN A.M.
- CORDANO A.
- COUSINS R.
- CRAFT N.E.
- CUNNINGHAM J.
- D'OCON C.D.
- DAMERON C.T.
- DANKS D.M.
- DAVIES N.T
- DiPAOLO D.V.
- FAILLA M.L.
- FAILLA M.L.
- FAILLA M.L.
- FAILLA M.L.
- FAYEK K.I.
- FESTA M.D.
- FIELDS M.
- FIELDS M.
- FIELDS M.
- FISCHER P.W.F.
- GALLAGER C.H.
- GILLERY P.
- GODIN D.V.
- GUGLIUCCI A.
- HAGGLOF B.
- HALL A.C.
- HALLMANS G.
- HART E.B.
- HASSEL C.A.
- HENRY R.R.
- HOFFMAN H.N.
- HOLECEK V.
- JAIN S.K.
- JANKOWSKI M.A.
- KAJANACHUMPOL S.
- KLEVAY L.M.
- LAU A.L.
- Lucia de Fátima Campos Pedrosa
- LYNCH S.M.
- MADIA A.M.
- MASON K.E.
- McARDLE H.J.
- McDERMOTT B.M.
- McDERMOTT B.M.
- MEARRIC P.T.
- MILLER D.S.
- MILLER F.N.
- NOTO R.
- O'DELL B.L.
- OESTREICHER P.
- PEDROSA L.F.C.
- PERCIVAL S.S.
- PIDDUCK H.
- PROHASKA J.R.
- PROHASKA J.R.
- PROHASKA J.R.
- PROHASKA J.R.
- REISER S.
- ROENSCH L.F.
- ROHN R.D.
- SAGGERSON E.D.
- SHIELDS G.S.
- SJÖGREN A.
- SJÖGREN A.
- STRAIN J.J.
- Sílvia Maria Franciscato Cozzolino
- TAYLOR C.G.
- THORNALLEY P.
- TORRE M.
- TURNLUND J.R.
- TWARDOWSKA-SAUCHA K.
- VILTER R.W.
- WACHNIK A.
- WALTER R.M.
- WEINER A.L.
- WERMAN M.J.
- WERMAN M.J.
- WILLIAMS D.M.
- WILLIAMS N.R.
- YAZIGI A.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Borrelioses, agentes e vetores
- Author
- Abel I.S.
- Aberer E.
- Ackermann R.
- Adivaldo H. Fonseca
- Afzelius A.
- Anderson B.E.
- Anderson J.F.
- Anderson J.F.
- Anderson J.F.
- Appel J.G.
- Appel M.J.G.
- Austin F.E.
- Azulay R.D.
- Azuma Y.
- Baker-Zander S.
- Balashov Y.S.
- Baranton G.
- Barbour A.G.
- Barbour A.G.
- Barbour A.G.
- Barbour A.G.
- Barbour A.G.
- Barboza W.G.A.
- Barros P.J.L.
- Battaly G.R.
- Battesti D.M.
- Benach J.L.
- Benach J.L.
- Bennett C.E.
- Benxiu J.
- Benxiu J.
- Berger B.W.
- Bernard W.V.
- Binder E.
- Blowey R.W.
- Blowey R.W.
- Bonoldi V.L.N.
- Bosler E.M.
- Bouseman J.K.
- Breitschwerdt E.B.
- Brumpt E.
- Buchwald A.
- Burgdorfer W.
- Burgdorfer W.
- Burgdorfer W.
- Burgdorfer W.
- Burgdorfer W.
- Burgess E.C.
- Burgess E.C.
- Burgess E.C.
- Burman N.
- Butler J.F.
- Callister S.M.
- Callow L.L.
- Canica M.M.
- Cerri D.
- Chen S.
- Chu H.J.
- Ciceroni L.
- Cleber O. Soares
- Cohen N.D.
- Cohen N.D.
- Costa I.P.
- Coughlin R.T.
- Coyle P.K.
- Craft J.E.
- Craft J.E.
- Dalgliesh R.J.
- Dawson J.E.
- Diab F.M.
- Dodge R.W.
- Donoghue A.R.
- Dorward D.W.
- Dressler F.
- Dumler J.S.
- Duray P.H.
- Engstrom S.M.
- Eremeeva M.
- Euzeby J.P.
- Ewing C.
- Falco C.R.
- Falco C.R.
- Falco C.R.
- Felsenfeld O.
- Fikrig E.
- Filgueira A.L.
- Fingerle V.
- Fonseca A.H.
- Fonseca A.H.
- Fonseca A.H.
- Fonseca A.H.
- Frank J.C.
- Garcia-Monco J.C.
- Garcia-Monco J.C.
- Garin C.H.
- Garnham P.C.C.
- Gern L.
- Gill J.S.
- Golighthly M.G.
- Grauer G.F.
- Greene R.T.
- Greene R.T.
- Greene R.T.
- Grodzicki R.L.
- Grund S.
- Gustafson J.M.
- Hard S.
- Hellerstrom S.
- Hellerstrom S.
- Herxheimer K.
- Hoogstraal H.
- Hoogstraal H.
- Hubalek Z.
- Hyde F.W.
- Iqbal Z.
- Iqbal Z.
- Irvin A.D.
- Ishikawa M.M.
- Ishikawa M.M.
- Isogai E.
- Jaenson T.G.T.
- Jaenson T.G.T.
- Jobe D.A.
- Jobe D.A.
- Johnson R.C.
- Johnson R.C.
- Joppert A.M.
- Kantor F.S.
- Karch H.
- Kawabata H.
- Kawabata M.
- Kimura K.
- Koch H.T.
- Kornblatt A.N.
- Kramer L.D.
- Krieg N.R.
- Kuiper H.
- Kurtenbach K.
- Lane R.S.
- Lane R.S.
- Lane R.S.
- Lane R.S.
- Lane R.S.
- Le Fleche A.
- Lebech A.M.
- Lebech A.M.
- Lemos E.R.S.
- Levy S.A.
- Levy S.A.
- Levy S.A.
- Lewengrub S.
- Lienbling M.R.
- Lipschultz B.
- Lissman B.A.
- Lopes C.W.G.
- Lord R.D.
- Ma J.
- Madigan J.E.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Magnarelli L.A.
- Manweiler S.A.
- Marcia M. Ishikawa
- Marconi R.T.
- Marcus L.C.
- Massard C.L.
- Mast W.E.
- Masuzawa T.
- Masuzawa T.
- Mather T.N.
- Mather T.N.
- Matton P.
- Matuschka F.R.
- Maupin G.O.
- Mckenna P.
- Mclean D.M.
- Mclean R.G.
- Meredith S.E.O.
- Mitchell P.D.
- Miyamoto K.
- Miyamoto K.
- Moter S.E.
- Mouritsen C.L.
- Nakao M.
- Nakao M.
- Nakayama Y.
- Natalino H. Yoshinari
- Neitz W.O.
- Nicholls T.H.
- Ogden N.H.
- Oksi J.
- Oliver Jr. J.H.
- Olsen B.
- Osebold J.W.
- Pachner A.R.
- Pachner A.R.
- Parker J.L.
- Pavlovsky E.N.
- Pfister H.W.
- Piesman J.
- Piesman J.
- Piesman J.
- Postic D.
- Pêssoa S.B.
- Quinn P.J.
- Rahn D.W.
- Randolph S.E.
- Randolph S.E.
- Rasiah C.
- Restrepo B.I.
- Ribeiro J.M.C.
- Ribeiro J.M.C.
- Ribeiro J.M.C.
- Richter Jr P.J.
- Rikihisa Y.
- Roitt I.
- Rothwell J.T.
- Russell H.
- Schoeler G.B.
- Schwan T.G.
- Schwartz B.S.
- Schwartz B.S.
- Sexton D.J.
- Shih C.M.
- Shih C.M.
- Shih C.M.
- Silva A.M.
- Smith R.D.
- Smith R.D.
- Smith T.
- Soares C.O.
- Sonenshine D.E.
- Sood S.K.
- Spach D.H.
- Spielman A.
- Spielman A.
- Stafford K.C.
- Stanchi N.O.
- Steere A.C.
- Steere A.C.
- Steere A.C.
- Steere A.C.
- Stiernstedt G.T.
- Takada N.
- Takahashi K.
- Talhari S.
- Talleklint L.
- Telford S.R.
- Telford S.R.
- Telford S.R.
- Uilenberg G.
- Urioste S.
- Van Der Ploeg L.H.T.
- Versiani V.
- Vivas R.I.R.
- Walker D.H.
- Walker E.D.
- Wallis R.C.
- Wang G.
- Weber K.
- Wells S.J.
- Willians L.R.
- Wouda W.
- Yevich S.J.
- Yoshinari N.H.
- Yoshinari N.H.
- Yoshinari N.H.
- Yoshinari N.H.
- Yoshinari N.H.
- Yoshinari N.H.
- Zaher
- Zbinden R.
- Zingg B.C.
- Zung J.L.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Managing climate variability in agriculture: Using weather forecasting to support farming adaptation
- Publication venue
- 'SAGE Publications'
- Publication date
- 01/03/2014
- Field of study
Recent unseasonal weather events and assessments of the potential impacts of climate change and variability on agriculture reveal that there is a pressing need to consider the range of adaptation options available to farmers, including their technical suitability, economic viability and environmental impact. This paper reviews the potential role of weather forecasting with reference to agriculture, including a brief assessment of its current status and uptake, its suitability and target use, issues associated with investment and benefit, and the constraints to wider uptake
Numerical study of turbulent diesel flow in a pipe with sudden expansion
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Portfolio Effects and Valuation of Weather Derivatives
- Author
- Publication venue
- Publication date
- 01/02/2006
- Field of study
In a mean-variance framework, the indifference pricing approach is adopted to value weather derivatives, taking account of portfolio effects. Our analysis shows how the magnitude of portfolio effects is related to the correlation between weather indexes and other risky assets, the correlation between weather indexes, and the payoff structures of the existing weather derivatives in an investor's asset portfolio. We also conduct some preliminary empirical analysis. This study contributes to the weather derivative pricing literature by incorporating both the hedgeable and unhedgeable parts of weather risks in illustrating the portfolio effects on the indifference prices of weather derivatives. Copyright 2006 by the Eastern Finance Association.
Insulin resistance and gray matter volume in neurodegenerative disease
- Author
- Aarsland
- Aarsland
- Abdul-Ghani
- Araki
- Ashburner
- Ashburner
- Banks
- Benedict
- Braak
- Burns
- Burns
- Burns
- Cheng
- Craft
- D.K. Johnson
- den Heijer
- Dubois
- E.D. Vidoni
- Gasparini
- Genuth
- Hirvonen
- Honea
- Hu
- Hughes
- J.K. Morris
- J.M. Burns
- Jewell
- Jin
- K. Lyons
- Lee
- Levy
- Liu
- Martin
- McKhann
- Moloney
- Morris
- Ott
- Prentki
- R. Pahwa
- R. Rada
- R.A. Honea
- R.D. Perea
- Ramaker
- Reger
- Ristow
- Samuel
- Schernhammer
- Shirk
- Simon
- Skeberdis
- Steen
- Suntrup
- Takahashi
- Talbot
- Thambisetty
- Turner
- van der Heide
- Wallace
- Wan
- Weintraub
- Willette
- Wu
- Xu
- Xu
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Female Tubal Sterilization
- Author
- A. Alvarado
- A.A. Kady El
- A.H. Hosseinian
- A.M. Siegler
- C. Chi
- C.M. March
- C.M. March
- Centers for Disease Control and Prevention.
- D. Sokal
- D.C. Pantaleoni
- D.E. Tourgeman
- D.E. Townsend
- D.L. Moyer
- D.P. Allyn
- D.T. Hieu
- E.D. Lichter
- F. DeStefano
- F. Mikulicz-Radecki von
- F.D. Loffer
- G.M. Filshie
- G.P. Gentile
- G.R. Quinones
- H.B. Peterson
- H.B. Peterson
- H.E. Miracle-McMahill
- H.J. Lindemann
- I. Craft
- I.-c. Chi
- I.-c. Chi
- I.B. Yoon
- J. Brundin
- J. Hamou
- J. Kocks
- J. Zipper
- J.B. Dubuisson
- J.F. Hulka
- J.F. Kerin
- J.M. Cooper
- J.M. Cooper
- J.M. Cooper
- JJ Kjer
- K. Edstrom
- K. Semm
- L.G. Escobedo
- M.C. Rulin
- M.J. Novy
- M.K. Goldhaber
- P. Feldblum
- R. Bhatt
- R. Soderstrom
- R.F. Valle
- R.M. Richart
- R.M. Richart
- R.M. Soderstrom
- S.D. Hillis
- T.P. Reed III
- W. Sweeney III
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2006
- Field of study
Controversies Surrounding Androgen Deprivation for Prostate Cancer
- Author
- Boccardo F.
- Bolla M.
- Borg A.
- Bruchovsky N.
- Bubley G.J.
- Buchanan G.
- Byar D.P.
- Byar D.P.
- Colombel M.
- Cook T.
- Coppage WS
- Craft N.
- Craft N.
- Crawford E.D.
- Crook J.M.
- Daniell H.W.
- Danielsen C.C.
- Denis L.J.
- Denmeade S.R.
- Eisenberger M.A.
- Feldman B.J.
- Fletcher J.M.
- Geller J.
- Geller J.
- Goldenberg S.L.
- Granfors T.
- Gregory C.W.
- Grossfeld G.D.
- Higano C.S.
- Hodgkinson A.
- Horwich A.
- Immediate versus deferred treatment for advanced prostatic cancer: initial results of the Medical Research Council Trial.
- Isaacs J.T.
- Janknegt R.A.
- Jordan WP
- Kiratli B.J.
- Klotz L.H.
- Koivisto P.
- Labrie F.
- Labrie F.
- Lowe F.C.
- Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials.
- McDonnell T.J.
- McGuire W.L.
- McLeod D.
- Messing E.M.
- Moinpour C.M.
- Moyad M.A.
- Nair B.
- Noble R.L.
- Oefelein M.G.
- Pantelides M.L.
- Pietras R.J.
- Pilepich M.V.
- Pound C.R.
- Raynaud J.P.
- Robinson M.R.
- Rothwell N.J.
- Ruijter E.
- Sandford N.L.
- Sandow J.
- Schmitt B.
- Seidenfeld J.
- Seidenfeld J.
- Slusser W.N.
- Small E.J.
- Soloway M.S.
- Stege R.
- Stricker H.J.
- Taplin M.E.
- Taplin M.E.
- Tayek J.A.
- Tilley W.D.
- Tomera K.
- Trachtenberg J.
- Treatment and survival of patients with cancer of the prostate.
- Veldscholte J.
- Verhas M.
- Visakorpi T.
- Walsh P.C.
- Wink C.S.
- Yeh S.
- Young HH
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Non-dietary correlates and determinants of plasma lutein and zeaxanthin concentrations in the Irish population
- Author
- A. M. O’Halloran
- A. Perry
- A. Prado-Cabrero
- A.J. Wenzel
- B. Lin
- B. Munoz
- B. Olmedilla-Alonso
- B. Olmedilla-Alonso
- B.A. Clevidence
- B.J. Whelan
- B.R. Hammond
- B.R. Hammond
- C.C.W. Klaver
- C.R. Gale
- Central Statistics Office.
- Central Statistics Office.
- D. Kelly
- D.E. King
- D.I. Thurnham
- D.M. Snodderly
- E. Loane
- E.D. O’Connell
- E.J. Johnson
- E.J. Johnson
- E.Y. Chew
- F. Khachik
- G. Crichton
- G.J. Handelman
- J. Dallongeville
- J. Feeney
- J. Feeney
- J. Kimmons
- J. Loughman
- J. Loughman
- J. M. Nolan
- J. Stack
- J.A. Mares
- J.A. Mares-Perlman
- J.D. Burke
- J.F. Keaney Jr
- J.M. Nolan
- J.M. Nolan
- J.M. Nolan
- J.M. Nolan
- J.M. Nolan
- J.M. Seddon
- J.M. Stringham
- J.V. Woodside
- K. O. Akuffo
- K.A. Meagher
- K.J. Yeum
- K.O. Akuffo
- K.O. Akuffo
- L.M. Renzi
- M. Gruber
- M. Trieschmann
- M.L. Kirby
- N. Congdon
- N.E. Craft
- N.I. Krinsky
- P.M. Kearney
- R. A. Kenny
- R. Mulcahy
- R. Vishwanathan
- R. Vishwanathan
- R. Vishwanathan
- R.A. Bone
- R.A. Bone
- R.L. Bailey
- R.S. Parker
- Rachel Moran
- S. Beatty
- S. Goulinet
- S. Pratt
- S. Sabour-Pickett
- S.M. George
- S.M. Moeller
- W. Millar
- W. Wei
- W.E. Brady
- W.K. Al-Delaimy
- W.M.R. Broekmans
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study