477 research outputs found

    Recognition of Cherenkov patterns in high multiplicity environments

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    An algorithm for the recognition of Cherenkov patterns based on the Hough Transform Method (HTM), modified for signals with intrinsic width in presence of background, is presented. The method basically consists in a mapping of the pad coordinate space directly to the Cherenkov angle parameter space with a crucial increase of performance in the treatment of different pattern shapes and amount of background. The method has been developed in the framework of the ALICE experiment at CERN for the analysis of data taken in the HMPID (High Momentum Particle IDentification) RICH detector prototype test beam

    Performance of large area CsI-RICH prototypes for ALICE at LHC

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    We present the performances of large area CsI-RICH prototypes obtained in single particle events. The differential quantum efficiency of the photocathodes has been deduced from Cherenkov rings by means of two different procedures: a direct measurement with a thin NaF radiator and a Monte Carlo based estimation for a C6_6F14_{14} radiator. A factor of merit of 45 cm1^{-1} has been found for the typical detector configuration. Two angle reconstruction algorithms have been used and the different errors affecting the Cherenkov angle resolution have been estimated combining the analytical treatment and the Monte Carlo simulation. Also the dependence on radiator thickness, Cherenkov ring radius, chamber voltage and particle incidence angle has been studied

    A pattern recognition method for the RICH-based HMPID detector in ALICE

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    A pattern recognition method developed for the High Momentum Particle IDentification (HMPID) detector in the ALICE experiment at CERN is presented. The algorithm is based on the Hough transform with a mapping of the pad coordinate space directly to the Cherenkov angle parameter space. Cherenkov angle reconstruction has been studied as a function of different particle densities in the photodetector using real data taken in the ALICE tests at the CERN SPS: a satisfactory resolution can be achieved even in events where the occupancy reaches more than 12, which is the situation we may be confronted with in central Pb-Pb interactions at LHC. (9 refs)

    Expression of E6/E7 HPV-DNA, HPV-mRNA and colposcopic features in management of CIN2/3 during pregnancy

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    The incidence of abnormal cervical cytology in pregnancy is similar to that reported for non-pregnant women. Furthermore, 1% of pregnant women annually screened for cervical cancer will be diagnosed with cervical intraepithelial neoplasia (CIN) of various degrees. For this reason, Pap smear should be performed in the first trimester of pregnancy. The persistence of HR-HPV infection is related to the development of CIN. However, the relationship between CIN and HR-HPV infection during pregnancy and postpartum can hardly be found. The aim of this work was to assess the proper management of abnormal cytology during and after pregnancy evaluating regression rate, persistence rate and risk of progression and the predictive role of HPV molecular tests

    A large area CsI RICH Detector in ALICE at LHC

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    A 1m2 CsI RICH prototype has been successfully tested in a hadron beam at CERN SPS. The prototype, fully equipped with 15k electronic channels, has been used to identify particles coming from pi-Be interactions. Track reconstruction has been performed by using a telescope consisting of four gas pad chambers. A detailed description of the detector will be presented and results from the test will be discussed.List of figuresFigure 1 Expected proton and antiproton yields including jet quenching mechanism in central Pb-Pb collisions at LHC.Figure 2 Schematic view of the HMPID CsI-RICHFigure 3 Experimental layout used at the SPS/H4 test beamFigure 4 Distributions of the mean number, per ring, of pad hits (Npad), electrons (Ntot) and Cherenkov photoelectrons (Nres) as a function of the single-electron mean pulse heightFigure 5 Mean single-electron pulse height as a function of high voltage measured at the centre of each of the four photocathodesFigure 6 Evaluation of the uniformity of the chamber gain for the photocathode PC32Figure 7 Azimuthal distribution of the photon pad hits in the Cherenkov fiducial zone (HV=2050 V)Figure 8 Photon angle (a) and track Cherenkov angle (b) distributions for beam events at the SPSFigure 9 Track density on the HMPID cathode plane in real 350 GeV/c pi--Be eventsFigure 10 Three dimensional display of an SPS 350 GeV/c pi--Be event. Eleven tracks are reconstructed in the telescope by requiring one hit on each pad chamber to reconstruct a track</UL

    The STAR-RICH Detector

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    The STAR-RICH detector extends the particle idenfication capabilities of the STAR spectrometer for charged hadrons at mid-rapidity. It allows identification of pions and kaons up to ~3 GeV/c and protons up to ~5 GeV/c. The characteristics and performance of the device in the inaugural RHIC run are described

    Vertical Dimension Control in Two Different Treatment Protocols: Invisalign First and Bite Block—A Retrospective Study

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    background: the aim of the present study was to compare the vertical dimension changes, before and after treatment, in two groups of growing patients, one group treated with clear aligner therapy versus a group treated with quad-helix and bite-block therapy. methods: the studied sample was composed of n. 40 patients (20 females and 20 males with a mean age of 8.6 ± 1.8 years), enrolled from the department of orthodontics at policlinico of rome tor vergata. the original sample was randomly divided into two groups: group IF (invisalign first) and group BB (quad-helix and bite block). pre- (T0) and post-treatment (T1 after 12 months) lateral cephalograms were collected from all the selected patients. nine cephalometric parameters, both angular and linear, were measured and recorded for each cephalogram. results: no statistically significant changes were found between both the IF and BB groups at T0, while statistically significant changes were observed in both groups (BB and IF) between T0 and T1 (after 12 months of active therapy), p &lt; 0.005. conclusions: both therapies were able to control the patient’s vertical condition. to date, the use of conventional appliances seems to have slightly better efficacy in controlling the vertical dimension than aligner therapy

    Social Capital, Institutional Rules, and Constitutional Amendment Rates

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    Why are some constitutions amended more frequently than others? The literature provides few clear answers, as some scholars focus on institutional factors, whereas others emphasize amendment culture. We bridge this divide with new theoretical and empirical insights. Using data from democratic constitutions worldwide and U.S. state constitutions, we examine how social capital reduces the transaction costs imposed by amendment rules. The results indicate that constitutional rigidity decreases amendment frequency, but group membership, civic activism, and political trust can offset the effect of amendment rules. Our findings have important implications for scholars in public law, constitutional and democratic theory, and social movements

    Role of Interaction and Nucleoside Diphosphate Kinase B in Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Function by cAMP-Dependent Protein Kinase A

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    Cystic fibrosis results from mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP-dependent protein kinase A (PKA) and ATP-regulated chloride channel. Here, we demonstrate that nucleoside diphosphate kinase B (NDPK-B, NM23-H2) forms a functional complex with CFTR. In airway epithelia forskolin/IBMX significantly increases NDPK-B co-localisation with CFTR whereas PKA inhibitors attenuate complex formation. Furthermore, an NDPK-B derived peptide (but not its NDPK-A equivalent) disrupts the NDPK-B/CFTR complex in vitro (19-mers comprising amino acids 36-54 from NDPK-B or NDPK-A). Overlay (Far-Western) and Surface Plasmon Resonance (SPR) analysis both demonstrate that NDPK-B binds CFTR within its first nucleotide binding domain (NBD1, CFTR amino acids 351-727). Analysis of chloride currents reflective of CFTR or outwardly rectifying chloride channels (ORCC, DIDS-sensitive) showed that the 19-mer NDPK-B peptide (but not its NDPK-A equivalent) reduced both chloride conductances. Additionally, the NDPK-B (but not NDPK-A) peptide also attenuated acetylcholine-induced intestinal short circuit currents. In silico analysis of the NBD1/NDPK-B complex reveals an extended interaction surface between the two proteins. This binding zone is also target of the 19-mer NDPK-B peptide, thus confirming its capability to disrupt NDPK-B/CFTR complex. We propose that NDPK-B forms part of the complex that controls chloride currents in epithelia

    Purification of wastewater from biomass-derived syngas scrubber using biochar and activated carbons

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    Phenol is a major component in the scrubber wastewater used for syngas purification in biomass-based gasification plants. Adsorption is a common strategy for wastewater purification, and carbon materials, such as activated carbons and biochar, may be used for its remediation. In this work, we compare the adsorption behavior towards phenol of two biochar samples, produced by pyrolysis and gasification of lignocellulose biomass, with two commercial activated carbons. Obtained data were also used to assess the effect of textural properties (i.e., surface area) on phenol removal. Continuous tests in lab-scale columns were also carried out and the obtained data were processed with literature models in order to obtain design parameters for scale-up. Results clearly indicate the superiority of activated carbons due to the higher pore volume, although biomass-derived char may be more suitable from an economic and environmental point of view. The phenol adsorption capacity increases from about 65 m/g for gasification biochar to about 270 mg/g for the commercial activated carbon. Correspondingly, service time of commercial activated carbons was found to be about six times higher than that of gasification biochar. Finally, results indicate that phenol may be used as a model for characterizing the adsorption capacity of the investigated carbon materials, but in the case of real waste water the carbon usage rate should be considered at least 1.5 times higher than that calculated for phenol
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