1,309 research outputs found
Multichannel Kondo impurities in superconductors
We discuss the effect of multichannel Kondo impurities on superconductivity.
In the strong coupling regime such impurities are pairbreakers, in contrast to
the ordinary Kondo effect. Measurements of -suppression may help in
identifying impurities displaying this more exotic exchange coupling to the
conduction band.Comment: 3 pages, 4 figures, uuencoded compressed postscript file, submitted
to SCES'94 (Amsterdam
Two-Channel Kondo Lattice: An Incoherent Metal
The two-channel Kondo lattice model is examined with a Quantum Monte Carlo
simulation in the limit of infinite dimensions. We find non-fermi-liquid
behavior at low temperatures including a finite low-temperature single-particle
scattering rate, the lack of a fermi edge and Drude weight. However, the
low-energy density of electronic states is finite. Thus, we identify this
system as an incoherent metal. We discuss the relevance of our results for
concentrated heavy fermion metals with non-Fermi-Liquid behavior.Comment: LaTex, 5 pages, 3 Postscript files. Revision - in reference 5 and
6(a
Phase Diagram of the Two-Channel Kondo Lattice
The phase diagram of the two-channel Kondo lattice model is examined with a
Quantum Monte Carlo simulation in the limit of infinite dimensions.
Commensurate (and incommensurate) antiferromagnetic and superconducting states
are found. The antiferromagnetic transition is very weak and continuous;
whereas the superconducting transition is discontinuous to an odd-frequency
channel-singlet and spin-singlet pairing state.Comment: 5 pages, LaTeX and 4 PS figures (see also cond-mat/9609146 and
cond-mat/9605109
Magnetic moments of charged hyperons
Measurements of the magnetic moments of the Ξ−, Σ+ and Σ− baryons are presented. The values found are μΞ−=−.69±.04, μΣ+=2.31±.027 and μΣ−=−.89±.14, in units μN. The Ξ− and Σ− results are final, while the Σ+ value is based on a preliminary analysis of about 22% of the data sample.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87403/2/58_1.pd
NUP214-ABL1 mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins
The NUP214-ABL1 fusion protein is a constitutively active protein tyrosine kinase that is found in 6% of patients with T-cell acute lymphoblastic leukemia and that promotes proliferation and survival of T-lymphoblasts. Although NUP214-ABL1 is sensitive to ABL1 kinase inhibitors, development of resistance to these compounds is a major clinical problem, underlining the need for additional drug targets in the sparsely studied NUP214-ABL1 signaling network. In this work, we identify and validate the SRC family kinase LCK as a protein whose activity is absolutely required for the proliferation and survival of T-cell acute lymphoblastic leukemia cells that depend on NUP214-ABL1 activity. These findings underscore the potential of SRC kinase inhibitors and of the dual ABL/SRC kinase inhibitors dasatinib and bosutinib for treating of NUP214-ABL1 positive T-cell acute lymphoblastic leukemia. In addition, we used mass spectrometry to identify protein interaction partners of NUP214-ABL1. Our results strongly support that the signaling network of NUP214-ABL1 is distinct from that previously reported for BCR-ABL1. Moreover, we identify three NUP214-ABL1 interacting proteins, MAD2L1, NUP155, and SMC4, as strictly required for the proliferation and survival of NUP214-ABL1 positive T-cell acute lymphoblastic leukemia cells. In conclusion, this work identifies LCK, MAD2L1, NUP155 and SMC4 as four new potential drug targets in NUP214-ABL1 positive T-cell acute lymphoblastic leukemia
Development of Rapid Detection and Genetic Characterization of Salmonella in Poultry Breeder Feeds
Salmonella is a leading cause of foodborne illness in the United States, with poultry and poultry products being a primary source of infection to humans. Poultry may carry some Salmonella serovars without any signs or symptoms of disease and without causing any adverse effects to the health of the bird. Salmonella may be introduced to a flock by multiple environmental sources, but poultry feed is suspected to be a leading source. Detecting Salmonella in feed can be challenging because low levels of the bacteria may not be recovered using traditional culturing techniques. Numerous detection methodologies have been examined over the years for quantifying Salmonella in feeds and many have proven to be effective for Salmonella isolation and detection in a variety of feeds. However, given the potential need for increased detection sensitivity, molecular detection technologies may the best candidate for developing rapid sensitive methods for identifying small numbers of Salmonella in the background of large volumes of feed. Several studies have been done using polymerase chain reaction (PCR) assays and commercial kits to detect Salmonella spp. in a wide variety of feed sources. In addition, DNA array technology has recently been utilized to track the dissemination of a specific Salmonella serotype in feed mills. This review will discuss the processing of feeds and potential points in the process that may introduce Salmonella contamination to the feed. Detection methods currently used and the need for advances in these methods also will be discussed. Finally, implementation of rapid detection for optimizing control methods to prevent and remove any Salmonella contamination of feeds will be considered
Search for polarization in Ξ0 hyperons
Inclusive hyperon production by 400 GeV protons at Fermilab has shown that the hyperons are produced with significant polarization. However no polarization has been seen for Λ’s produced at these energies. In this paper we present the results of a searcch for Ξ0 polarization.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87405/2/126_1.pd
Cross-cultural validation of the Student Nurse Stress Index Scale:A descriptive survey targeting student nurses in China
Polarization of inclusively produced hyperons
We report here polarization results from a series of Fermilab experiments from the years 1974 through 1980, with some preliminary data from a high pT polarization experiment completed in February 1982. The Λ polarization has a remarkably simple and interesting behavior when expressed as a function of xF and pT.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87407/2/83_1.pd
Site-specific His/Asp phosphoproteomic analysis of prokaryotes reveals putative targets for drug resistance
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