Education, Health and Health-Related Behaviors: Evidence from Higher Education Expansion

This study throws light on the potential non-linear effects of education on individual health and health-related behaviors, finding a strong role for higher education. Using an instrumental variables (IVs) strategy, which leverages changes in within-province between-municipality college proximity across birth cohorts, we demonstrate that higher education affects individual health-related behavior. By contrast, IVs estimates based on a compulsory schooling age reform show mostly non-significant effects. Our results point to a complex link between education and health. On the one hand, higher education channels individuals into some healthy behaviors and better health outcomes namely healthy eating, more physical activity and a lower risk of obesity. On the other hand, it also appears to increase the prevalence of certain unhealthy behaviors, such as greater smoking and drinking prevalence and higher cigarettes consumption. Albeit effects are generally similar across genders, except in few cases (e.g. smoking behavior), our analysis highlights heterogeneous effects by age and helps explain potential differences in results reported in past quasi-experimental studies in which the cohorts affected by the educational reforms used for identification are observed at given ages and not over an individual’s entire lifecycle

Titan's Surface Temperatures from Cassini CIRS

The surface brightness temperature of Titan can be measured from Cassini through a spectral window at 19 microns where the atmosphere is low in opacity. The Composite Infrared Spectrometer (CIRS) on Cassini observes this wavelength in its far-infrared channel. Because the Cassini tour has provided global coverage and a range of viewing geometries, CIRS has been able to go beyond the earlier flyby results of Voyager IRIS Near the equator, CIRS measures the zonally-averaged surface brightness temperature to be 917 K, very close to the temperature found at the surface by Huygens. Latitude maps show that Titan's surface temperatures drop off by about 2 K toward the south and by about 3 K toward the north. This temperature distribution is consistent with Titan's late northern winter when the data were taken. As the seasons progress, CIRS is continuing to search for corresponding changes in the temperatures of the surface and lower atmosphere. CIRS is also extending global mapping to both latitude and longitude to look for correlations between surface temperatures and geological features

The Impact of Workplace Conditions on Firm Performance

This paper estimates the impact of work environment health and safety practice on firm performance, and examines which firm-characteristic factors are associated with good work conditions. We use Danish longitudinal register matched employer-employee data, merged with firm business accounts and detailed cross-sectional survey data on workplace conditions. This enables us to address typical econometric problems such as omitted variables bias or endogeneity in estimating i) standard production functions augmented with work environment indicators and aggregate employee characteristics and ii) firm mean wage regressions on the same explanatory variables. Our findings suggest that improvement in some of the physical dimensions of the work health and safety environment (specifically, “internal climate” and “repetitive and strenuous activity”) strongly impacts the firm productivity, whereas “internal climate” problems are the only workplace hazards compensated for by higher mean wages

Surface Temperatures on Titan; Changes During the Cassini Mission

Surface brightness temperatures on Titan measured by the Composite Infrared Spectrometer (CIRS) aboard Cassini span the period from late northern winter to early spring. The CIRS observations cover all latitudes and can be used to study meridional changes with season. CIRS previously reported surface temperatures from 2004-2008 which were 93.7 K at the equator with decreases of 2 K toward the south pole and 3 K toward the north pole'. From a comparison of the equinox period with the earlier data, CIRS can now detect a seasonal shift in the latitudinal distribution of temperatures. Around the time of the equinox the meridional distribution was more symmetric about the equator than had been found earlier in the mission. The equatorial surface temperatures remained close to 94 K, but in the south the temperatures had decreased by about 0.5 K and in the north had increased by about 0.5 K. The CIRS equinox results are similar to what was seen near the previous vernal equinox by Voyager IRIS Z. The observed surface temperatures can help constrain the type of surface material by comparison with predictions from general circulation models. Of the three cases treated by Tokano t , our measurements most closely match a porous-ice regolith. As Cassini continues through Titan's northern spring CIRS will extend its temporal and spatial coverage and will continue to search for seasonal variations in surface temperature

Seasonal Changes in Titan's Surface Temperatures

Cassini's extended mission has provided the opportunity to search for seasonal variations on Titan. In particular, surface temperatures are expected to have shifted significantly in latitude during the completed portion of the mission. Spectra recorded by the Composite Infrared Spectrometer (CIRS) during the nominal mission (2004-08) and the Equinox mission. (2008-10) have already shown changes in temperature. CIRS has detected a seasonal shift in the latitudinal distribution of surface brightness temperatures by comparing zonal averages from two time segments, one period in late northern winter centered on L(sub s) approximately 335 deg and a second period centered on the equinox (L(sub s) approximately 0 deg.). The earlier period had a meridional distribution similar to that previously reported: 93.5 K at the equator, 91.7 K at 85 S and 899 K at 85 N. The newly measured distribution near equinox shows a cooling in the south and a warming in the north, both by about 0.5 K. We estimate that. the centroid of the distribution moved from approximately 16 S to 7 S between the two periods. This gives a seasonal lag behind insolation of delta L(sub s) approximately 13 deg. The CIRS equinox results are consistent with those of Voyager IRIS, which encountered Titan in November 1980, just following the previous northern equinox (L(sub s) = 10 deg.). When compared with predictions from general circulation models, seasonal variations of surface temperature can help constrain the identification of surface materials. Our measurements most closely match the case of a porous ice regolith treated by Tokano, but with some apparent differences between the northern and southern hemispheres. CIRS will extend its study of seasonal variations in surface temperature on Titan as Cassini continues through northern spring

Seasonal Changes in Surface Temperatures on Titan

The surface brightness temperatures on Titan have been measured by the Composite Infrared Spectrometer (CIRS) aboard Cassini during the period spanning late northern winter through vernal equinox. CIRS observes radiance from the surface through a spectral window at 19 microns where the atmosphere has an opacity minimum [I]. CIRS is now seeing a shift in the latitudinal distribution of temperatures froth a distinctly warmer south to a more symmetrical north -south pattern, similar to that found by Voyager IRIS [2,3] at the time of the previous vernal equinox. Near the equator the temperatures remain close to the 93.7 K value found at the surface by Huygens [4]. From the equator to the poles the temperature gradients are 2-3 K. When compared with predictions froth general circulation models [5] the measured temperatures and their seasonal changes constrain the possible types of surface material. As Cassini continues through Titan's northern spring CiRS will extend its, global coverage to took for correlations between surface temperatures and albedo and to search for diurnal temperature variation

Robot assisted laparoscopic excision of a paraganglioma: new therapeutic approach

The Paraganglioma is the most common extra-adrenal pheochromocytoma arising from neural crest (1) (It will better to write: The paraganglioma is an extra-adrenal pheocromocytoma arising from the neural crest. 10% of pheocromocytomas are extra-adrenal and can arise form chromaffin tissue derived from primitive neuroectoderm). Minimally invasive techniques allow surgeons to perform the procedure without wide exposure and mobilization of intra abdominal organs. To our knowledge we present the third case of robotic excision of a retroperitoneal paraganglioma (2,3)

A Project to Promote English Learning in Primary School: “An English Island®” E-learning Platform

The present study was aimed to investigate English learning as second language, in school, in first, second and third graders of twelve classes randomly assigned to a control or an experimental group. Children in the latter are exposed during English school teaching to the method “An English Island®” and to its platform activities. The method “An English Island®” offers a variety of strategies for teaching English in primary school, an innovative digital tool that promotes teaching/learning English language’s communicative approach, lead students to become familiar with the language in a sort of continuous, inclusive workout, in which everyone participates and talks. English skills as well as cognitive abilities are tested in both groups at the beginning and at the end of the school year with the aim to compare control and experimental classes in both a longitudinal and a cross-sectional design

Alteration of glyoxalase genes expression in response to testosterone in LNCaP and PC3 human prostate cancer cells.

Glyoxalase system, a ubiquitous detoxification pathway protecting against cellular damage caused by potent cytotoxic metabolites, is involved in the regulation of cellular growth. Aberrations in the expression of glyoxalase genes in several human cancers have been reported. Recently, we described a possible regulatory effect by estrogens on glyoxalase genes in human breast cancer cell lines. This result, along with those ones regarding changes in glyoxalases activity and expression in other human hormone-regulated cancers, such as prostate cancer, has prompted us to investigate whether also androgens, whose functional role in prostate cancer pathogenesis is well known, could modulate glyoxalases gene expression. Therefore, we treated LNCaP androgen-responsive and PC3 androgen-independent human prostate cancer cell lines with testosterone at the concentrations of 1 nM and 100 nM. After a two days treatment, glyoxalases mRNA levels as well as cell proliferation were evaluated by real-time RT-PCR analysis and [3H]thymidine incorporation, respectively. Results pointed out that testosterone affects the expression of glyoxalase system genes and cell proliferation in a different manner in the two cell lines. The possibility that modulation of glyoxalase genes expression by testosterone is due to glyoxalases-mediated intracellular response mechanisms to the androgen-induced oxidative stress or to the presence of androgen response elements (ARE) in glyoxalase promoters are discussed. Knowledge regarding the regulation of glyoxalases by testosterone may provide insights into the importance of these enzymes in human prostate carcinomas in vivo

Pretransplant dyslipidaemia influences primary graft dysfunction after lung transplantation

OBJECTIVES: Primary graft dysfunction (PGD) is a major cause of mortality within the first year following lung transplantation. Pulmonary hypertension, elevated body mass index (BMI), prolonged ischaemic time of the graft, intraoperative blood transfusions >1000 ml and the use of cardiopulmonary bypass or extracorporeal membrane oxygenation increase the risk for PGD. We aimed to evaluate whether dyslipidaemia is an additional risk factor for the development of PGD. METHODS: We retrospectively analysed demographic and clinical data of 264 patients who received their first bilateral lung transplantation between March 2000 and October 2013 at our institution. The endpoint was PGD grade 3 at any time, defined according to the International Society for Heart and Lung Transplantation (ISHLT) criteria. Fasting lipid profiles at listing time or just before transplantation (baseline) were documented and dyslipidaemia was defined as any of the parameters being out of range. Comparisons of continuous variables between patients with PGD grade 3 and patients without were performed with the Mann-Whitney U-test, whereas proportions were compared with the χ(2) test. Continuous variables were presented as arithmetic means with standard deviation for ease of comparison, but levels of statistical significance were computed using the appropriate non-parametric statistical test. To identify PGD risk factors, a forward stepwise logistic regression model was used. RESULTS: PGD occurred in 63 recipients (24%). Pretransplant dyslipidaemia was documented in 153 recipients (58%) and was significantly more prevalent among recipients developing PGD (45 vs 108, P < 0.013). Despite various underlying pulmonary pathologies, higher triglyceride (TG) levels (1.41 ± 0.78 vs 1.16 ± 0.78, P < 0.012), lower high-density lipoprotein-cholesterol (HDL-C) concentrations (1.24 ± 0.55 vs 1.57 ± 0.71, P < 0.0005) and higher cholesterol/HDL-C values (3.80 ± 2.02 vs 3.00 ± 0.92, P < 0.0005) were associated with a lower incidence of PGD. Patients with PGD had significantly longer ischaemic time (350 ± 89 vs 322 ± 91, P = 0.017) and higher BMI (23 ± 5 vs 21 ± 4.4, P < 0.007). CONCLUSION: Dyslipidaemia seems to be an independent risk factor for PGD after lung transplantation: low circulating levels of HDL-C and hypertriglyceridaemia increase the incidence of PGD. Even if HDL-C levels are difficult to alter today, triglyceride and cholesterol levels can be addressed therapeutically and may have a positive influence on the development of PGD