Study of a micro chamber quadrupole mass spectrometer

Copyright @ 2008 American Vacuum Society / American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Journal of Vacuum Science and Technology Part A: International Journal Devoted to Vacuum, Surfaces, and Films, 26(2), Article number 239 and may be found at http://scitation.aip.org/content/avs/journal/jvsta/26/2/10.1116/1.2827512.The design of a micro chamberquadrupolemass spectrometer (MCQMS) having a small total volume of only 20 cm3, including Faraday cup ion detector and ion source, is described. This MCQMS can resist a vacuum baking temperature of 400–500 °C. The quadrupole elements with a hyperbolic surface are made of a ceramic material and coated with a thin metal layer. The quadrupole mass filter has a field radius of 3 mm and a length of 100 mm. Prototypes of this new MCQMS can detect a minimum partial pressure of 10−8 Pa, have a peak width of ΔM=1 at 10% peak height from mass number 1 to 60, and show an excellent long-term stability. The new MCQMS is intended to be used in residual gas analyses of electron devices during a mutual pumping and baking process.National Key Basic Research Program, the Chinese 111 Project Grant and Program for New Century Excellent Talents in University

The Redshift Distribution of FIRST Radio Sources at 1 mJy

We present spectra for a sample of radio sources from the FIRST survey, and use them to define the form of the redshift distribution of radio sources at mJy levels.We targeted 365 sources and obtained 46 redshifts (13 per cent of the sample). We find that our sample is complete in redshift measurement to R $\sim 18.6$, corresponding to $z\sim 0.2$. Early-type galaxies represent the largest subset (45 per cent) of the sample and have redshifts 0.15\la z \la 0.5 ; late-type galaxies make up 15 per cent of the sample and have redshifts 0.05\la z \la 0.2; starbursting galaxies are a small fraction ($\sim 6$ per cent), and are very nearby (z\la 0.05). Some 9 per cent of the population have Seyfert1/quasar-type spectra, all at z\ga 0.8, and there are 4 per cent are Seyfert2 type galaxies at intermediate redshifts ($z\sim 0.2$). Using our measurements and data from the Phoenix survey, we obtain an estimate for $N(z)$ at $S_{1.4 \rm {GHz}}\ge 1$ mJy and compare this with model predictions. At variance with previous conclusions, we find that the population of starbursting objects makes up \la 5 per cent of the radio population at S $\sim 1$ mJy.Comment: 20 pages, sumbitted to MNRA

Fermented beverages with health-promoting potential: Past and future perspectives

peer-reviewedFermentation is an ancient form of food preservation, which also improves the nutritional content of foods. In many regions of the world, fermented beverages have become known for their health-promoting attributes. In addition to harnessing traditional beverages for commercial use, there have recently been innovative efforts to develop non-dairy probiotic fermented beverages from a variety of substrates, including soy milk, whey, cereals and vegetable and fruit juices. On the basis of recent developments, it is anticipated that fermented beverages will continue to be a significant component within the functional food market

Sequencing-Based Analysis of the Bacterial and Fungal Composition of Kefir Grains and Milks from Multiple Sources

peer-reviewedKefir is a fermented milk-based beverage to which a number of health-promoting properties have been attributed. The microbes responsible for the fermentation of milk to produce kefir consist of a complex association of bacteria and yeasts, bound within a polysaccharide matrix, known as the kefir grain. The consistency of this microbial population, and that present in the resultant beverage, has been the subject of a number of previous, almost exclusively culture-based, studies which have indicated differences depending on geographical location and culture conditions. However, culture-based identification studies are limited by virtue of only detecting species with the ability to grow on the specific medium used and thus culture-independent, molecular-based techniques offer the potential for a more comprehensive analysis of such communities. Here we describe a detailed investigation of the microbial population, both bacterial and fungal, of kefir, using high-throughput sequencing to analyse 25 kefir milks and associated grains sourced from 8 geographically distinct regions. This is the first occasion that this technology has been employed to investigate the fungal component of these populations or to reveal the microbial composition of such an extensive number of kefir grains or milks. As a result several genera and species not previously identified in kefir were revealed. Our analysis shows that the bacterial populations in kefir are dominated by 2 phyla, the Firmicutes and the Proteobacteria. It was also established that the fungal populations of kefir were dominated by the genera Kazachstania, Kluyveromyces and Naumovozyma, but that a variable sub-dominant population also exists.The Alimentary Pharmabiotic Centre is a research centre funded by Science Foundation Ireland (SFI), through the Irish Government’s National Development Plan. The authors and their work were supported by SFI CSET grant APC CSET 2 grant 07/CE/B1368

Characteristics of Gamma-Ray Loud Blazars in the VLBA Imaging and Polarimetry Survey

The radio properties of blazars detected by the Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope have been observed as part of the VLBA Imaging and Polarimetry Survey (VIPS). This large, flux-limited sample of active galactic nuclei (AGN) provides insights into the mechanism that produces strong gamma-ray emission. At lower flux levels, radio flux density does not directly correlate with gamma-ray flux. We find that the LAT-detected BL Lacs tend to be similar to the non-LAT BL Lacs, but that the LAT-detected FSRQs are often significantly different from the non-LAT FSRQs. The differences between the gamma-ray loud and quiet FSRQs can be explained by Doppler boosting; these objects appear to require larger Doppler factors than those of the BL Lacs. It is possible that the gamma-ray loud FSRQs are fundamentally different from the gamma-ray quiet FSRQs. Strong polarization at the base of the jet appears to be a signature for gamma-ray loud AGN.Comment: 32 pages, 9 figures, accepted by Ap

Variational water-wave model with accurate dispersion and vertical vorticity

A new water-wave model has been derived which is based on variational techniques and combines a depth-averaged vertical (component of) vorticity with depth-dependent potential flow. The model facilitates the further restriction of the vertical profile of the velocity potential to n-th order polynomials or a finite-element profile with a small number of elements (say), leading to a framework for efficient modeling of the interaction of steepening and breaking waves near the shore with a large-scale horizontal flow. The equations are derived from a constrained variational formulation which leads to conservation laws for energy, mass, momentum and vertical vorticity. It is shown that the potential-flow water-wave equations and the shallow-water equations are recovered in the relevant limits. Approximate shock relations are provided, which can be used in numerical schemes to model breaking waves

In silico identification of bacteriocin gene clusters in the gastrointestinal tract, based on the Human Microbiome Project’s reference genome database

peer-reviewedBackground The human gut microbiota comprises approximately 100 trillion microbial cells which significantly impact many aspects of human physiology - including metabolism, nutrient absorption and immune function. Disturbances in this population have been implicated in many conditions and diseases, including obesity, type-2 diabetes and inflammatory bowel disease. This suggests that targeted manipulation or shaping of the gut microbiota, by bacteriocins and other antimicrobials, has potential as a therapeutic tool for the prevention or treatment of these conditions. With this in mind, several studies have used traditional culture-dependent approaches to successfully identify bacteriocin-producers from the mammalian gut. In silico-based approaches to identify novel gene clusters are now also being utilised to take advantage of the vast amount of data currently being generated by next generation sequencing technologies. In this study, we employed an in silico screening approach to mine potential bacteriocin clusters in genome-sequenced isolates from the gastrointestinal tract (GIT). More specifically, the bacteriocin genome-mining tool BAGEL3 was used to identify potential bacteriocin producers in the genomes of the GIT subset of the Human Microbiome Project’s reference genome database. Each of the identified gene clusters were manually annotated and potential bacteriocin-associated genes were evaluated. Results We identified 74 clusters of note from 59 unique members of the Firmicutes, Bacteroidetes, Actinobacteria, Fusobacteria and Synergistetes. The most commonly identified class of bacteriocin was the >10 kDa class, formerly known as bacteriolysins, followed by lantibiotics and sactipeptides. Conclusions Multiple bacteriocin gene clusters were identified in a dataset representative of the human gut microbiota. Interestingly, many of these were associated with species and genera which are not typically associated with bacteriocin production.CJW, CMG and PDC are supported by a SFI PI award to PDC “Obesibiotics” (11/PI/1137)

It’s the Methodology For Me: A Systematic Review of Early Approaches to Studying TikTok

Research on TikTok has grown along with the app’s rapidly rising global popularity. In this systematic review, we investigate 58 articles examining TikTok, its users, and its content. Focusing on articles published in journals and proceedings across the domains of human-computer interaction, communication, and other related disciplines, we analyze the methods being used to study TikTok, as well as ethical considerations. Based on our analysis, we found that research on TikTok tends to use content analysis as their primary method and mainly focus on user behavior and culture, effects of use, the platform’s policies and governance, and very few articles discuss the ethical implications of collecting and analyzing such data. Additionally, most studies employ traditional forms of data collection when the affordances of TikTok tend to differ from other social media platforms. We conclude with a discussion about possible future directions and contribute to ongoing conversations about ethics and social media data

An Euler Poincar\'e framework for the multilayer Green Nagdhi equations

The Green Nagdhi equations are frequently used as a model of the wave-like behaviour of the free surface of a fluid, or the interface between two homogeneous fluids of differing densities. Here we show that their multilayer extension arises naturally from a framework based on the Euler Poincare theory under an ansatz of columnar motion. The framework also extends to the travelling wave solutions of the equations. We present numerical solutions of the travelling wave problem in a number of flow regimes. We find that the free surface and multilayer waves can exhibit intriguing differences compared to the results of single layer or rigid lid models