9 research outputs found

    Senior Recital-Emily Cottam

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    https://digitalcommons.usu.edu/music_programs/1016/thumbnail.jp

    Concerto Evening, Celebrating the Winners of the Annual Student Concerto Competition

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    Celebrating the Winners of the Annual Student Concerto Competitionhttps://digitalcommons.usu.edu/music_programs/1000/thumbnail.jp

    Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.

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    BACKGROUND: Remote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown to reduce myocardial infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). We investigated whether remote ischaemic conditioning could reduce the incidence of cardiac death and hospitalisation for heart failure at 12 months. METHODS: We did an international investigator-initiated, prospective, single-blind, randomised controlled trial (CONDI-2/ERIC-PPCI) at 33 centres across the UK, Denmark, Spain, and Serbia. Patients (age >18 years) with suspected STEMI and who were eligible for PPCI were randomly allocated (1:1, stratified by centre with a permuted block method) to receive standard treatment (including a sham simulated remote ischaemic conditioning intervention at UK sites only) or remote ischaemic conditioning treatment (intermittent ischaemia and reperfusion applied to the arm through four cycles of 5-min inflation and 5-min deflation of an automated cuff device) before PPCI. Investigators responsible for data collection and outcome assessment were masked to treatment allocation. The primary combined endpoint was cardiac death or hospitalisation for heart failure at 12 months in the intention-to-treat population. This trial is registered with ClinicalTrials.gov (NCT02342522) and is completed. FINDINGS: Between Nov 6, 2013, and March 31, 2018, 5401 patients were randomly allocated to either the control group (n=2701) or the remote ischaemic conditioning group (n=2700). After exclusion of patients upon hospital arrival or loss to follow-up, 2569 patients in the control group and 2546 in the intervention group were included in the intention-to-treat analysis. At 12 months post-PPCI, the Kaplan-Meier-estimated frequencies of cardiac death or hospitalisation for heart failure (the primary endpoint) were 220 (8·6%) patients in the control group and 239 (9·4%) in the remote ischaemic conditioning group (hazard ratio 1·10 [95% CI 0·91-1·32], p=0·32 for intervention versus control). No important unexpected adverse events or side effects of remote ischaemic conditioning were observed. INTERPRETATION: Remote ischaemic conditioning does not improve clinical outcomes (cardiac death or hospitalisation for heart failure) at 12 months in patients with STEMI undergoing PPCI. FUNDING: British Heart Foundation, University College London Hospitals/University College London Biomedical Research Centre, Danish Innovation Foundation, Novo Nordisk Foundation, TrygFonden

    A Stiff, Brocaded Gown: Patterns in the Life of Amy Lowell

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    Amy Lowell\u27s poetry serves as a reflection of the challenges and struggles that permeated her life. Her late entry into the world of published poetry at the age of 38 resulted in the presentation of already-solidified beliefs that she had developed since childhood. Although the techniques she employed and the quality of her writing varied in the last decades of her life, Lowell\u27s focus on imagery, rhythm, and mood remained consistent in many of her works. Published in 1916, the poem Patterns , from Men, Women, and Ghosts, contains themes that are of particular note when placed into the context of Lowell\u27s life. Besides the obvious references to her anti-war sentiment and the unabashed employment of sensual language as descriptive tools, Patterns places a spotlight on the issues that had repeatedly come to plague Lowell\u27s life. The cycle of life and death, the unstoppable force of time, the conflict of living as a female in society with pervasive pressures of conformity, and fears of never finding love as a social outcast and homosexual woman are all patterns in Amy Lowell\u27s life that assert themselves in this particular poem. The ostentatious nature of her writing also serves as a reflection of the lifestyle and performance decisions she made in her journey as a nationally-acclaimed poet. Through her frequent employment of descriptive language and her strong focus on pacing, verse, and rhythm, Amy Lowell addresses the subjects of sensuality, social conformity, death, and anti-war sentiment in Patterns . This poem is an accurate representation of the life values and poetic aesthetic that she attempted to exude during her lifetime, for she felt that the poet with originality and power is always seeking to give his readers the same poignant feeling which he has himself.

    Migration of a sewing needle foreign body into the brainstem of a cat

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    Case summary A 1-year-old, female spayed domestic shorthair cat with a 6 week history of upper respiratory signs and a progressive reluctance to move, which culminated in a right-sided hemiparesis, was found to have a sewing needle foreign body lodged in the brainstem. Surgical extraction of the needle was successful and the cat’s neurological deficits resolved over the days to weeks following its removal. Relevance and novel information This case report describes, to our knowledge, the first reported incidence and management of an ingested sewing needle migrating into the central nervous system of a cat

    Drain Detectives : Lessons Learned from Citizen Science Monitoring of Beach Drains

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    Stormwater drains are common features at city beaches. Stormwater impact from drains is well understood, but the extent and impact of dry-weather flows on water quality and therefore on swimmers is not. Traditional beach monitoring may not be sensitive or frequent enough to assess this risk from drains, and investigation of dry-weather pollution is limited by relatively slow turnaround times for laboratory analysis. This case study describes lessons learned from a trial of citizen science and water quality sensors to monitor drains for dry-weather flows. This involved the use of smartphones and data-collection platforms for community monitoring at signed drains and by trained citizen scientists. Monitoring consisted of photos, observations, and water sampling. A key lesson from the trial was how citizen science can enhance data collected by sensors or by traditional monitoring. Citizen scientists collected data that sensors could not provide on flows, such as size and colour at outlets, and whether flows reached the bay. When combined with sensor data, drains were risk profiled, with higher-risk drains investigated further. Another lesson learned was to adequately resource in-person engagement and communications to motivate and retain citizen scientists. Underestimating resources for engagement translated into less data collected. Community data from signs was a valuable addition, but could have been maximised by simplifying data collection and ensuring signs were close to where observations or photos needed to be taken. The approaches trialled and lessons learned from this project are informative for the design and delivery of similar projects.</p
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