The meaning of religious beliefs for a group of cancer patients during rehabilitation

Este estudo exploratório teve o objetivo de identificar como a religião influencia a sobrevivência de um grupo de pacientes oncológicos. Consistiu em estudo de caso etnográfico, com a participação de seis laringectomizados, de ambos os sexos, na faixa etária de 51 a 72 anos, operados de dois a cinco anos. Os dados foram coletados por entrevistas semi-estruturadas e analisados segundo os conceitos de cultura e religião. Sintetizou-se os resultados em três categorias descritivas: a representação moral do câncer, as crenças religiosas na trajetória do câncer e a negociação com a religião para a sobrevivência. O significado que emerge - "a expectativa por uma segunda chance" - enfatiza a importância da religião como parte das redes de apoio que se articulam com o enfrentamento do estigma do câncer, com a expectativa da cura e com as formas de organizar a vida cotidiana, na sobrevivência.La finalidad de este estudio exploratorio fue identificar cómo la religión influencia la supervivencia de un grupo de pacientes oncológicos. Consistió en un estudio de caso etnográfico con la participación de seis laringectomizados, de ambos sexos, con edad de 51 a 72 años, que habían sido operados de dos a cinco años antes. Los datos fueron recogidos por entrevistas semi-estructuradas y analizados según los conceptos de cultura y religión. Sintetizamos los resultados en tres categorias descriptivas: la representación moral del cáncer, las creencias religiosas en el trayecto del cáncer y la negociación con la religión por la supervivencia. El significado que resulta - "la expectativa por una segunda oportunidad" - enfatiza la importancia de la religión como parte de las redes de apoyo que se encadenan con la conciliación con el estigma del cáncer, con la expectativa de cura y con las formas de arreglar la vida cotidiana, en la supervivenvia.The objective of this exploratory study was to identify how religion influences the survival of a group of cancer patients. The study consisted of an ethnographic case with the participation of six laryngectomized male and female patients between 51 and 72 years old, who had been operated on two to five years earlier. Data were collected by semistructured interviews and analyzed on the basis of the concepts of culture and religion. The results were synthesized into three descriptive categories: the moral representation of cancer, religious beliefs about the cancer trajectory, and negotiation with religion for survival. These categories give rise to the meaning "the hope for a second chance", which emphasizes the importance of religion as part of the support networks that articulate with the patient's coping with the stigma of cancer, with the hope for cure, and with the ways of organizing everyday life, during survival

The Bacterium Endosymbiont of Crithidia deanei Undergoes Coordinated Division with the Host Cell Nucleus

In trypanosomatids, cell division involves morphological changes and requires coordinated replication and segregation of the nucleus, kinetoplast and flagellum. In endosymbiont-containing trypanosomatids, like Crithidia deanei, this process is more complex, as each daughter cell contains only a single symbiotic bacterium, indicating that the prokaryote must replicate synchronically with the host protozoan. In this study, we used light and electron microscopy combined with three-dimensional reconstruction approaches to observe the endosymbiont shape and division during C. deanei cell cycle. We found that the bacterium replicates before the basal body and kinetoplast segregations and that the nucleus is the last organelle to divide, before cytokinesis. In addition, the endosymbiont is usually found close to the host cell nucleus, presenting different shapes during the protozoan cell cycle. Considering that the endosymbiosis in trypanosomatids is a mutualistic relationship, which resembles organelle acquisition during evolution, these findings establish an excellent model for the understanding of mechanisms related with the establishment of organelles in eukaryotic cells

Influence of sense of coherence on adolescents' self-perceived dental aesthetics:a cross-sectional study

Background Sense of coherence (SOC) is a psychosocial factor capable of influencing perception of health, improving one’s ability to manage life. It is the central construct of salutogenesis. SOC allows for identification and mobilization of resources to effectively manage or solve problems, promoting health and quality of life. Using Wilson-Cleary’s conceptual model we hypothesized that SOC might contribute to self-perception of dental aesthetics. The aim of this study was to investigate whether SOC levels were related to self-perception of dental aesthetics against assessed normative orthodontic treatment need among adolescents. Methods A cross-sectional study was conducted with 615 male and female adolescents aged 12 to 15 years. Data collection comprised socio-demographic and socio-economic characteristics, SOC (SOC 13), self-perceived dental aesthetics (Oral Aesthetic Subjective Impact Scale), and assessment of orthodontic treatment need (Dental Aesthetic Index). Statistical analysis involved Pearson’s chi-square test, Kruskal-Wallis test, Mann-Whitney test and multiple linear regression. Spearman’s correlation coefficient was calculated for the determination of the strength of correlations among the numerical variables. The level of significance was set at 5% (p < 0.05). Results 50.1% of the participants were classified as having a high SOC (≥ median). Overall, SOC was associated with self-perceived dental aesthetics (p = 0.048). In the adolescents with no orthodontic treatment need, those with a low SOC perceived their dental aesthetics more negatively than those with high levels of SOC. The multiple regression analysis demonstrated an inverse relationship between SOC and: 1) age (p = 0.007), SOC being higher in the younger age group; 2) self-perceived dental aesthetics (p = 0.001), a higher SOC being associated with those who had a positive dental self-perception. Conclusions SOC was associated with self-perceived dental aesthetics and adolescents with a high SOC were more likely to perceive their dental aesthetics more positively. SOC did not seem to influence self-perception of dental aesthetics in adolescents who were clinically assessed as having an orthodontic treatment need, however, in those where there was no orthodontic treatment need, a low SOC was associated with a negative self-perception of dental appearance