415 research outputs found
Trust in financial markets : the role of the human element
Purpose – This paper suggests that the human element is key when it comes to investors’ trust in financial markets. Ignoring it may jeopardise the effectiveness of the recent regulatory growth. The study takes a demand-based perspective, assuming the relationship between financial advisors and investors is based upon trust, and it analyses the conditions that may lead to the existence (or not) of trust. Design/methodology/approach – Using a fuzzy-set qualitative comparative analysis (fsQCA) of data collected from 366 questionnaires, we are able to test, in a qualitative non-parametric way, the conditional arguments that may lead investors to trust (or not) their financial advisor. Findings – The results show that trust conditions differ, depending on the degree of investors’ participation in financial markets. The way investors with a basic relationship with financial markets perceive the behaviour of their financial advisors is key in establishing (or not) their trust. For investors with a more advanced relationship with the market, trust (or its absence) also depends on investors’ characteristics. In particular, their financial literacy plays a morethan-negligible role. The joint analysis of the conditions leading to trust and its absence highlights the robustness of our findings. Originality/value – By understanding the conditions that establish trust, financial institutions can design strategies to strengthen the level of investors’ confidence in their services, improving the relationship between market players, and increasing business. From the supervisory authorities’ point of view, the approval of a code of conduct for financial advisors, taking into account our results, can help improve the overall trust in financial markets. To the best of our knowledge, this study is the first to apply Butler’s (1991) psychometric scale and the fsQCA methodology to study investors’ trust in financial advisors.info:eu-repo/semantics/publishedVersio
Seroprevalence of coxiella burnetii in dairy cattle and buffalo from southern italy
A cross-sectional survey was carried out in dairy cattle and buffalo herds from the Southern Italy to detect antibodies against Coxiella burnetii. From 2014 to 2018, 402 herds were monitored and 50 mL of bulk-tank milk (BTM) per farm was analyzed by indirect ELISA. Blood samples of animals from positive farms were also taken and analyzed with the same ELISA test. The overall seroprevalence was 35% [95% Confidence interval (CI):30-39] at herd level and 13% (95%CI:13-14) at animal level. Herd province seroprevalences ranged from 17% to 75%. The provinces of Matera (71%, 95%CI:38-105) and Agrigento (75%, 95%CI:51-100) showed the highest percentage of infected farms. These results describe the widespread distribution of C. burnetii in livestock from Southern Italy, highlighting the need to implement a monitoring program for Q fever
Reproductive disorders induced by Chlamydophila spp. infections in an italian mediterranean buffalo (bubalus bubalis) herd
The Italian Mediterranean Buffalo (Bubalus bubalis) has low fecundity and high incidence of abortion. Several studies have associated reproductive failure of water buffalo with viral infections but there is limited information on the role of chlamydial infections. To investigate the presence and the role of Chlamydiaceae in water buffalo a retrospective study was performed in a farm where, in the arch of 11 months, the pregnant heifers suffered an abortion rate of 36.8% in the 3rd and 5th month of pregnancy. Antibodies to Chlamydiaceae were detected in 57% of the aborted cows, while the rate of positivity was 0% in overtly healthy cows used as control. By a PCR assay 3 of 14 vaginal swabs from aborted animals tested positive for Chlamydophila agents and, additionally, 3 out of 7 aborted foetuses tested positive for Chlamydophila spp., with two being co-infections by Cp. abortus and Cp. pecorum and one being characterised as Cp. abortus. The presence of anti-Chlamydiaceae antibodies in 57% of the aborted animals and the detection of Chlamydophila agents in foetal organs and in vaginal swabs is consistent with the history of abortions (P<0.002) observed in the herd and may suggest a pathogenic role by Chlamydophila spp. in water buffalo
A new parsimonious AHP methodology: assigning priorities to many objects by comparing pairwise few reference objects
We propose a development of the Analytic Hierarchy Process (AHP) permitting to use the methodology also for decision problems with a very large number of alternatives and several criteria. While the ap- plication of the original AHP method involves many pairwise comparisons between considered objects, that can be alternatives with respect to considered criteria or criteria between them, our parsimonious proposal is composed of five steps: (i) direct evaluation of the objects at hand; (ii) selection of some reference objects; (iii) application of the original AHP method to the reference objects; (iv) check of the consistency of the pairwise comparisons of AHP and the compatibility between the rating and the prior- itization with a subsequent discussion with the decision maker who can modify the rating or pairwise comparisons of reference objects; (v) revision of the direct evaluation on the basis of the prioritization supplied by AHP on reference objects. Our approach permits to avoid the distortion of comparing more relevant objects (reference points) with less relevant objects. Moreover, our AHP approach avoids rank reversal problems, that is, changes of the order in the prioritizations due to adding or removing one or more objects from the set of considered objects. The new proposal has been tested and experimentally validated
Ceftolozane-tazobactam combination therapy compared to ceftolozane-tazobactam monotherapy for the treatment of severe infections: A systematic review and meta-analysis
Ceftolozane-tazobactam (C/T) is a combination of an advanced-generation cephalosporin (ceftolozane) with a β-lactamase inhibitor (tazobactam). It is approved for the treatment of compli-cated urinary-tract/intra-abdominal infections and hospital-acquired/ventilator-associated pneumo-nia. This systematic review and meta-analysis (registered prospectively on PROSPERO, no. CRD42019134099, on 20 January 2020) aimed to evaluate the effectiveness of C/T combination therapy compared to C/T monotherapy for the treatment of severe infections and to describe the prevalence of microorganisms in the included studies. We retrieved literature from PubMed, EMBASE, and CENTRAL, until 26 November 2020. Eligible studies were both randomised trials and nonrandomised studies with a control group, published in the English language and peer-reviewed journals. The primary outcome was all-cause mortality; secondary outcomes were (i) clinical improvement and (ii) microbiological cure. Eight nonrandomised studies were included in the qualitative synthesis: Seven retrospective cohort studies and one case-control study. The meta-analysis of the four studies evaluating all-cause mortality (in total 148 patients: 87 patients treated with C/T alone and 61 patients treated with C/T combination therapy) showed a significant reduction of mortality in patients receiving C/T combination therapy, OR: 0.31, 95% CI: 0.10–0.97, p = 0.045. Conversely, the meta-analysis of the studies evaluating clinical improvement and microbiological cure showed no differences in C/T combination therapy compared to C/T monotherapy. The most consistent data come from the analysis of the clinical improvement, n = 391 patients, OR: 0.97, 95% CI: 0.54–1.74, p = 0.909. In 238 of the 391 patients included (60.8%), C/T was used for the treatment of infections caused by Pseudomonas aeruginosa
Antibiotics or no antibiotics, that is the question: An update on efficient and effective use of antibiotics in dental practice
The antimicrobial resistance (AMR) phenomenon is an emerging global problem and is induced by overuse and misuse of antibiotics in medical practice. In total, 10% of antibiotic prescriptions are from dentists, usually to manage oro-dental pains and avoid postsurgical complications. Recent research and clinical evaluations highlight new therapeutical approaches with a reduction in dosages and number of antibiotic prescriptions and recommend focusing on an accurate diagnosis and improvement of oral health before dental treatments and in patients’ daily lives. In this article, the most common clinical and operative situations in dental practice, such as endodontics, management of acute alveolar abscesses, extractive oral surgery, parodontology and implantology, are recognized and summarized, suggesting possible guidelines to reduce antibiotic prescription and consumption, maintaining high success rates and low complications rates. Additionally, the categories of patients requiring antibiotic administration for pre-existing conditions are recapitulated. To reduce AMR threat, it is important to establish protocols for treatment with antibiotics, to be used only in specific situations. Recent reviews demonstrate that, in dentistry, it is possible to minimize the use of antibiotics, thoroughly assessing patient’s conditions and type of intervention, thus improving their efficacy and reducing the adverse effects and enhancing the modern concept of personalized medicine
Trust in Financial Markets: the Role of the Human Element
Purpose – This paper suggests that the human element is key when it comes to investors’ trust in financial markets. Ignoring it may jeopardise the effectiveness of the recent regulatory growth. The study takes a demand-based perspective, assuming the relationship between financial advisors and investors is based upon trust, and it analyses the conditions that may lead to the existence (or not) of trust.
Design/methodology/approach – Using a fuzzy-set qualitative comparative analysis (fsQCA) of data collected from 366 questionnaires, we are able to test, in a qualitative non-parametric way, the conditional arguments that may lead investors to trust (or not) their financial advisor.
Findings – The results show that trust conditions differ, depending on the degree of investors’ participation in financial markets. The way investors with a basic relationship with financial markets perceive the behaviour of their financial advisors is key in establishing (or not) their trust. For investors with a more advanced relationship with the market, trust (or its absence) also depends on investors’ characteristics. In particular, their financial literacy plays a more-than-negligible role. The joint analysis of the conditions leading to trust and its absence highlights the robustness of our findings.
Originality/value – By understanding the conditions that establish trust, financial institutions can design strategies to strengthen the level of investors’ confidence in their services, improving the relationship between market players, and increasing business. From the supervisory authorities’ point of view, the approval of a code of conduct for financial advisors, taking into account our results, can help improve the overall trust in financial markets. To the best of our knowledge, this study is the first to apply Butler’s (1991) psychometric scale and the fsQCA methodology to study investors’ trust in financial advisors
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