“Who Cares?”: the acceptance of decentralized wastewater systems in regions without water problems

There is a growing interest in decentralized wastewater treatment systems, especially in regions with water scarcity problems or water management issues. This study aims to determine whether the perceived advantages and disadvantages (leading to acceptance) of decentralized wastewater plants in such regions are the same in regions where the population is not aware of these water issues. Firstly, this study systematically reviews previous findings on public perceptions of the acceptance of decentralized wastewater treatment systems. Then, the study details the results of a focus group study to determine whether the elements identified in the literature are also relevant in a region where people are unaware of water problems. The results show that a lack of awareness of water issues seems to be a critical factor influencing acceptance. Reframing the usefulness of these systems by focusing on other aspects, such as environmental sustainability, is key.info:eu-repo/semantics/publishedVersio

Mixed bird flocks: patterns of activity and species composition in a region of the Central Andes of Colombia Bandadas mixtas de aves: patrones de actividad y composición de especies en una región de la Cordillera Central de los Andes de Colombia

Mixed bird flocks are groups of individuals from different species that travel and forage together. Such groups are common in several bird communities around the world. We present species composition and activity patterns of mixed bird flocks in a region of the Central Andes of Colombia. We compared the number of species per flock, as well as the number of flocks among 3 different habitats. We tested hypotheses concerning the flocks daily activity and the co-occurrences of species within them. We recorded 75 species, and the species number per flock varied from 4 to 21. Our data suggest that habitat affects the number of flocks but not their species number, and that the activity of flocks is similar throughout the day. In addition, the association of birds in flocks is affected by interspecific facilitation, with some species co-occurrences found more times than expected by chance. We hypothesize that some tanager species could have a role in flock cohesion. We witnessed 2 predator attacks upon flocks, a number of agonistic interactions among flock members, and squirrels following bird flocks. Our results meet some general patterns described for mixed bird flocks.Las bandadas mixtas de aves son grupos de individuos de diferentes especies que viajan y forrajean juntos, y son comunes en varias comunidades de aves alrededor del mundo. Presentamos la composición de especies y los patrones de actividad de las bandadas mixtas de aves en una región de la Cordillera Central de los Andes Colombianos. Comparamos el número de especies por bandada y el número de bandadas en 3 hábitats distintos. Evaluamos hipótesis relacionadas con la actividad de las bandadas durante el día y la presencia simultánea de especies en estos grupos. Observamos 75 especies, y el número de especies por bandada varió entre 4 y 21. Nuestros datos indican que el hábitat parece afectar el número de bandadas pero no su número de especies y que la actividad de las bandadas es similar durante el día. La asociación de especies en bandadas parece estar influida por facilitación intraespecífica y algunas especies se presentan simultáneamente más de lo esperado por azar. Hipotetizamos que algunas tangaras pueden tener un papel en la cohesión de las bandadas. Observamos 2 ataques de depredadores, así como varias interacciones hostiles entre miembros de las bandadas y la participación de ardillas. Nuestros resultados se ajustan a ciertos patrones descritos para las bandadas mixtas

Spatial attention and conscious perception: the role of endogenous and exogenous orienting

Attention has often been considered to be a gateway to consciousness (Posner, Proceedings of the National Academy of Sciences of the United States of America, 91(16), 7398-7403, 1994). However, its relationship with conscious perception (CP) remains highly controversial. While theoretical models and experimental data support the role of attention in CP (Chica, Lasaponara, Lupi\ue1\uf1ez, Doricchi, & Bartolomeo, NeuroImage, 51, 1205-1212, 2010; Dehaene, Changeux, Naccache, Sackur, & Sergent, Trends in Cognitive Sciences, 10, 204-211, 2006; Mack & Rock, Inattentional blindness, 1998), recent studies have claimed that at least some forms of attention--endogenous or top-down spatial attention--are neither sufficient nor necessary for CP (Koch & Tsuchiya, Trends in Cognitive Sciences, 11, 16-22, 2007). In the present experiments, we demonstrate the importance of exogenously triggered attention for the modulation of CP. Weak or null effects were instead observed when attention was triggered endogenously. Our data are discussed in the framework of recent neuropsychological models (Dehaene et al., Trends in Cognitive Sciences, 10, 204-211, 2006), postulating that activity within reverberating frontoparietal networks, as colocalized with spatial-orienting systems, is the brain correlate of consciously processed information

A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival

Data de publicació electrònica: 06-08-2021The cell division cycle 25A (CDC25A) phosphatase is a key regulator of cell cycle progression that acts on the phosphorylation status of Cyclin-Cyclin-dependent kinase complexes, with an emergent role in the DNA damage response and cell survival control. The regulation of CDC25A activity and its protein level is essential to control the cell cycle and maintain genomic integrity. Here we describe a novel ubiquitin/proteasome-mediated pathway negatively regulating CDC25A stability, dependent on its phosphorylation by the serine/threonine kinase DYRK2. DYRK2 phosphorylates CDC25A on at least 7 residues, resulting in its degradation independent of the known CDC25A E3 ubiquitin ligases. CDC25A in turn is able to control the phosphorylation of DYRK2 at several residues outside from its activation loop, thus affecting DYRK2 localization and activity. An inverse correlation between DYRK2 and CDC25A protein amounts was observed during cell cycle progression and in response to DNA damage, with CDC25A accumulation responding to the manipulation of DYRK2 levels or activity in either physiological scenario. Functional data show that the pro-survival activity of CDC25A and the pro-apoptotic activity of DYRK2 could be partly explained by the mutual regulation between both proteins. Moreover, DYRK2 modulation of CDC25A expression and/or activity contributes to the DYRK2 role in cell cycle regulation. Altogether, we provide evidence suggesting that DYRK2 and CDC25A mutually control their activity and stability by a feedback regulatory loop, with a relevant effect on the genotoxic stress pathway, apoptosis, and cell cycle regulation.This work was funded by Ministerio de Ciencia e Innovación (SAF2016-75228-R to MAC and BFU2016-76141-P to SdlL) and by Cancer Research UK (C52419/A22869) to LdlV. MLC and ACS were supported by a FPU fellowship (FPU13/03393 and FPU18/00845, respectively) from the Ministerio de Educación y Formación Profesional