Derivation of Soil Roughness Using Multi-Temporal Laser Scanning Point Clouds

The present paper deals with the derivation of roughness parameters of soil from laser scanning point clouds, allowing to draw conclusions about properties of the soil (e. g. soil aggregation, soil sealing) and related to this its vulnerability to soil erosion. For this purpose, soil erosion scenes with agricultural cultivation are acquired in five measuring epochs under field conditions. For geo-referencing of the acquired time series of point clouds, a target-based and a data-driven approach are compared. In order to derive roughness parameters, the point clouds are cleaned of vegetation and then modelled to reduce the measurement noise. For this purpose, a collocation-based approach is used, in which a trend surface roughly approximates the point clouds. Remaining systematic deviations, which are caused by the insufficient functional approximation, are caught with the help of a stochastic signal, the variances and correlations lengths of which simultaneously provide information about the soil’s roughness

Comparative Analysis of Algorithms to Cleanse Soil Micro-Relief Point Clouds

Detecting changes in soil micro-relief in farmland helps to understand degradation processes like sheet erosion. Using the high-resolution technique of terrestrial laser scanning (TLS), we generated point clouds of three 2 × 3 m plots on a weekly basis from May to mid-June in 2022 on cultivated farmland in Germany. Three well-known applications for eliminating vegetation points in the generated point cloud were tested: Cloth Simulation Filter (CSF) as a filtering method, three variants of CANUPO as a machine learning method, and ArcGIS PointCNN as a deep learning method, a sub-category of machine learning using deep neural networks. We assessed the methods with hard criteria such as F1 score, balanced accuracy, height differences, and their standard deviations to the reference surface, resulting in data gaps and robustness, and with soft criteria such as time-saving capacity, accessibility, and user knowledge. All algorithms showed a low performance at the initial measurement epoch, increasing with later epochs. While most of the results demonstrate a better performance of ArcGIS PointCNN, this algorithm revealed an exceptionally low performance in plot 1, which is describable by the generalization gap. Although CANUPO variants created the highest amount of data gaps, we recommend that CANUPO include colour values in combination with CSF

Trends in Occurrence and Phenotypic Resistance of Coagulase-Negative Staphylococci (CoNS) Found in Human Blood in the Northern Netherlands between 2013 and 2019

Background: For years, coagulase-negative staphylococci (CoNS) were not considered a cause of bloodstream infections (BSIs) and were often regarded as contamination. However, the association of CoNS with nosocomial infections is increasingly recognized. The identification of more than 40 different CoNS species has been driven by the introduction of matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. Yet, treatment guidelines consider CoNS as a whole group, despite increasing antibiotic resistance (ABR) in CoNS. This retrospective study provides an in-depth data analysis of CoNS isolates found in human blood culture isolates between 2013 and 2019 in the entire region of the Northern Netherlands. Methods: In total, 10,796 patients were included that were hospitalized in one of the 15 hospitals in the region, leading to 14,992 CoNS isolates for (ABR) data analysis. CoNS accounted for 27.6% of all available 71,632 blood culture isolates. EUCAST Expert rules were applied to correct for errors in antibiotic test results. Results: A total of 27 different CoNS species were found. Major differences were observed in occurrence and ABR profiles. The top five species covered 97.1% of all included isolates: S. epidermidis, S. hominis, S. capitis, S. haemolyticus, and S. warneri. Regarding ABR, methicillin resistance was most frequently detected in S. haemolyticus (72%), S. cohnii (65%), and S. epidermidis (62%). S. epidermidis and S. haemolyticus showed 50–80% resistance to teicoplanin and macrolides while resistance to these agents remained lower than 10% in most other CoNS species. Conclusion: These differences are often neglected in national guideline development, prompting a focus on ‘ABR-safe’ agents such as glycopeptides. In conclusion, this multi-year, full-region approach to extensively assess the trends in both the occurrence and phenotypic resistance of CoNS species could be used for evaluating treatment policies and understanding more about these important but still too often neglected pathogens

A prospective multicentre screening study on multidrug-resistant organisms in intensive care units in the Dutch-German cross-border region, 2017 to 2018:the importance of healthcare structures

BACKGROUND: Antimicrobial resistance poses a risk for healthcare, both in the community and hospitals. The spread of multidrug-resistant organisms (MDROs) occurs mostly on a local and regional level, following movement of patients, but also occurs across national borders. AIM: The aim of this observational study was to determine the prevalence of MDROs in a European cross-border region to understand differences and improve infection prevention based on real-time routine data and workflows. METHODS: Between September 2017 and June 2018, 23 hospitals in the Dutch (NL)–German (DE) cross-border region (BR) participated in the study. During 8 consecutive weeks, patients were screened upon admission to intensive care units (ICUs) for nasal carriage of meticillin-resistant Staphylococcus aureus (MRSA) and rectal carriage of vancomycin-resistant Enterococcus faecium/E. faecalis (VRE), third-generation cephalosporin-resistant Enterobacteriaceae (3GCRE) and carbapenem-resistant Enterobacteriaceae (CRE). All samples were processed in the associated laboratories. RESULTS: A total of 3,365 patients were screened (median age: 68 years (IQR: 57–77); male/female ratio: 59.7/40.3; NL-BR: n = 1,202; DE-BR: n = 2,163). Median screening compliance was 60.4% (NL-BR: 56.9%; DE-BR: 62.9%). MDRO prevalence was higher in DE-BR than in NL-BR, namely 1.7% vs 0.6% for MRSA (p = 0.006), 2.7% vs 0.1% for VRE (p < 0.001) and 6.6% vs 3.6% for 3GCRE (p < 0.001), whereas CRE prevalence was comparable (0.2% in DE-BR vs 0.0% in NL-BR ICUs). CONCLUSIONS: This first prospective multicentre screening study in a European cross-border region shows high heterogenicity in MDRO carriage prevalence in NL-BR and DE-BR ICUs. This indicates that the prevalence is probably influenced by the different healthcare structures

DaF-/DaZ-/DaM-Bildungsräume. Sprech- & Textformen im Fokus

Der Sammelband besteht aus zwei Teilen: Der erste Teil befasst sich mit der Universität als Bildungsraum für zukünftige Lehrpersonen. Hier interessiert, wie diese Adressatengruppe mithilfe wissenschaftlich fundierter Ansätze auf einen professionellen Umgang mit sprachlich heterogenen Unterrichtsanforderungen vorbereitet werden kann. Im zweiten Teil werden verschiedene Dimensionen sprachbildenden Unterrichts in den Fächern Deutsch, Geschichte, Biologie und Mathematik näher ausdifferenziert. Unter der Prämisse, dass die Verfügbarkeit hinreichend entwickelter sprachlicher Kompetenzen in allen Fächern als conditio sine qua non für den Bildungserfolg zählt, setzen sich alle Beiträge mit einzelnen Sprech- und Textformen zu bestimmten Themen sowie mit diesbezüglichen Fördermaßnahmen auseinander

Unique Features of a Global Human Ectoparasite Identified Through Sequencing of the Bed Bug Genome

The bed bug, Cimex lectularius, has re-established itself as a ubiquitous human ectoparasite throughout much of the world during the past two decades. This global resurgence is likely linked to increased international travel and commerce in addition to widespread insecticide resistance. Analyses of the C. lectularius sequenced genome (650 Mb) and 14,220 predicted protein-coding genes provide a comprehensive representation of genes that are linked to traumatic insemination, a reduced chemosensory repertoire of genes related to obligate hematophagy, host-symbiont interactions, and several mechanisms of insecticide resistance. In addition, we document the presence of multiple putative lateral gene transfer events. Genome sequencing and annotation establish a solid foundation for future research on mechanisms of insecticide resistance, human-bed bug and symbiont-bed bug associations, and unique features of bed bug biology that contribute to the unprecedented success of C. lectularius as a human ectoparasite