Conduite d'approche in conduction aphasia: Which psycholinguistic and experimental variables drive it – A case study.

Conduite d’approche (CdA) is a classic repetitive behavior reported frequently in persons with conduction aphasia, however, relatively little is known about it, both at the brain and cognitive level (e.g., whether it is a self-correcting mechanism based on comprehension or rather on production, Nickels and Howard, 1995; Ueno and Lambon-Ralph, 2013). In this work we address which psycholinguistic and experimental variables boost the occurrence of CdAs and are involved in reaching a successful CdA. Here we study ANC, a 79-year-old male with high sociocultural level who suffers from a reproduction conduction aphasia that caused frequent CdAs.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Cold vapour generation electrothermal atomic absorption spectrometry and solid phase extraction based on a new nanosorbent for sensitive HG determination in environmental samples (sea water and river water)

Reunión bianual del Grupo Regional Andaluz de la Sociedad Española de Química AnalíticaMercury is not an essential element for plant or animal life and it is a potential environmental toxic because of its tendency to form covalent bonds with organic molecules and the high stability of the Hg-C bond. Reports estimate a total mercury concentration in natural waters ranging from 0.2 to 100 ng L-1. Due to this fact, highly sensitive methods are required for direct determination of such extremely low levels. In this work, a rapid and simple method was developed for separation and preconcentration of mercury by flow injection solid phase extraction coupled with on-line chemical vapour generation electrothermal atomic absorption spectrometry. The system is based on chelating retention of the analyte onto the mini column filled with a mesoporous silica functionalized with 1,5 bis (di-2-pyridyl) methylene thiocarbohydrazide. The main aim of this work was to develop a precise and accurate method for the determination of the Hg. Under the optima conditions and 120 s preconcentration time, the detection limit obtained was 0.009 μg L-1, with RSDs 3.7 % for 0.2 μg L-1, 4.8 % for 1 μg L-1 and enrichment factor 4, Furthermore, the method proposed has permitted the determination of Hg with a reduction in the analysis time, the sample throughput was about 18 h-1, low consumption of reagents and sample volume. The method was applied to the determination of Hg in sea water and river water. For the quality control of the analytical performance and the validation of the newly developed method, the analysis of two certified samples, TMDA 54.4 Fortified Lake, and LGC6187 River sediment was addressed. The results showed good agreement with the certified values.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Determination of Pb using F3eO4 GO join to DPTH for ferrofluid based dispersive solid phase extraction

In this work has been described a green and rapid method the synthesis of Fe3O4@GO nanospheres via chemical covalent bonding method. The Fe3O4@GO DPTH was applied to ferrofluid based dispersive solid phase extraction of lead as a model analyte using an ionic liquid carrier. The ferro fluid allows the rapid extraction of lead ions using a low amount of sorbent material. Besides, the magnetic separation greatly improved the separation rate. The presented method is highly time saving due to the high dispersion of the sorbent in the aqueous phase and also there is no need to shake the sample solution. The other benefits of the proposed methods are simplicity of operation, low cost, high sorption capacity, high recovery and high preconcentration. In order to optimize the method the following parameters were studied: sample solution pH, concentration of DPTH, extraction time, amount of sorbent, desorption conditions, influence of ionic strength, and tolerance of potentially interfering ions. The sample or standard solution containing Pb(II), DPTH (0.05% ethanol w/v), NaCl (0.5 %, w/v) and buffer (pH = 5.6) was poured into high volume. Then 240 µL of ferrofluid was injected rapidly into the sample solution through a syringe. Thereupon, a dark cloudy suspension was formed, ferrofluid was dispersed thoroughly in solution and the complex of Pb-DPTH was extracted in a few seconds. Subsequently, a strong magnet was placed at the bottom of the tube to let the extractant settle. After about 3 min, the solution became clear and the supernatant was discarded simply by decanting it. Afterwards, the magnet was removed and 1 mL of nitric acid (2.0 mol L−1) was introduced to the vial to desorb the Pb by sonication. Finally, the sorbent was separated by positioning the magnet to the outside of the tube and the concentration of Pb in acidic aqueous phase was determined by ETAAS.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Requisitos de almacenamiento de información e identificación de actores para una biblioteca digital de bienes muebles

Desarrollar una biblioteca digital no es una tarea sencilla. En ella intervienen técnicos y expertos que deben tener una fluida comunicación que permita que el sistema resultante se adecue a las necesidades del usuario. Este trabajo presenta las necesidades de almacenamiento que requiere una biblioteca digital para la gestión del patrimonio mueble andaluz, así como la identificación de los actores que van a interactuar con el sistema. Al final del trabajo se presenta una aproximación metodológica para el desarrollo de sistemas para el tratamiento de bibliotecas digitales que se está elaborando en el contexto del proyecto de investigación MADEIRA(Metodologías y Arquitecturas para la Difusión Electrónica de Información por la Red )Ministerio de Ciencia y Tecnología Madeira TIC2000-1673-C06-0

Aplicación Integrada de la Biblioteca Digital del Patrimonio Histórico Andaluz

En este trabajo se describen las necesidades del Instituto Andaluz de Patrimonio Histórico para desarrollar el Sistema de Información Integrado de Patrimonio Histórico Andaluz. El objetivo es crear un sistema de acceso y gestión uniforme a la información dispersa en diversas bases de datos que han sido creadas por grupos de trabajo independientes. Para ello, se propone un modelo de arquitectura, basado en XML, que permite el acceso uniforme a bases de datos heterogéneas y distribuidas

A Kinetic Model Considering Catalyst Deactivation for Methanol-to-Dimethyl Ether on a Biomass-Derived Zr/P-Carbon Catalyst

A Zr-loaded P-containing biomass-derived activated carbon (ACPZr) has been tested for methanol dehydration between 450 and 550 °C. At earlier stages, methanol conversion was complete, and the reaction product was mainly dimethyl ether (DME), although coke, methane, hydrogen and CO were also observed to a lesser extent. The catalyst was slowly deactivated with time-on-stream (TOS), but maintained a high selectivity to DME (>80%), with a higher yield to this product than 20% for more than 24 h at 500 °C. A kinetic model was developed for methanol dehydration reaction, which included the effect of the inhibition of water and the deactivation of the catalyst by coke. The study of stoichiometric rates pointed out that coke could be produced through a formaldehyde intermediate, which might, alternatively, decompose into CO and H2. On the other hand, the presence of 10% water in the feed did not affect the rate of coke formation, but produced a reduction of 50% in the DME yield, suggesting a reversible competitive adsorption of water. A Langmuir–Hinshelwood reaction mechanism was used to develop a kinetic model that considered the deactivation of the catalyst. Activation energy values of 65 and 51 kJ/mol were obtained for DME and methane production in the temperature range from 450 °C to 550 °C. On the other hand, coke formation as a function of time on stream (TOS) was also modelled and used as the input for the deactivation function of the model, which allowed for the successful prediction of the DME, CH4 and CO yields in the whole evaluated TOS interval.This research was supported by the Spanish Ministry of Science, Innovation and Universities and Junta de Andalucia through RTI2018-097555-B-I00 and UMA18-FEDERJA-110 projects, respectively. J.T.-L. also acknowledges the assistance of the Spanish Ministry of Economy, Industry and Competitiveness for the award of a predoctoral contract to become a Ph.D. (BES-2016-079237). Partial funding for open access charge: Universidad de Málag

Sincronización de estros en ovejas mediante protocolo de 6 días con CIDR de primera, segunda y tercera reutilización

Estrus synchronization( is a vital strategy in sheep production and is accomplished most often via controlled internal drug release (CIDR) devices. Reuse of CIDR devices can reduce operating costs and ewe exposure to progesterone (P4), but remains controversial. A comparison was made of the effects of new and reused natural progesterone-releasing intravaginal (CIDR) devices in six-day protocols on reproductive performance variables and blood serum progesterone concentrations in multiparous ewes. A total of 172 sheep (average body weight = 59 kg) were randomly distributed into four treatments: CIDR1 (control group, new devices), CIDR2 (second-use), CIDR3 (third-use) and CIDR4 (fourth-use). The variables ewes in estrus, pregnancy rate, fertility rate and parturition type did not differ (P>0.05) between treatments. Estrus onset was later (P≤0.05) in CIDR1 (40 ± 10 h) than in CIDR2 (31 ± 9 h).  Ewes in estrus ranged from 93 to 100 %,  average pregnancy rate was 80.8 %, average fertility  rate was 80.2 % and the prolificacy index was 1.26. The single delivery rate was higher (P≤0.05) than the double delivery rate in all four treatments. Intravaginal CIDR devices can be used in ewes up to four times in six-day estrus synchronization protocols without affecting reproductive variables.El objetivo del estudio fue comparar el efecto de dispositivos intravaginales liberadores de progesterona natural (CIDR) nuevos y reutilizados en protocolos de 6 días sobre el desempeño reproductivo y en las concentraciones de progesterona en suero sanguíneo de ovejas multíparas. Un total de 172 ovejas con peso corporal promedio de 59 kg se distribuyeron al azar en cuatro tratamientos: CIDR1 (grupo testigo con dispositivos nuevos) y CIDR2, CIDR3, CIDR4 (con 6, 12 y 18 días de uso, respectivamente). En cuanto al inicio de estro, hubo diferencia (P≤0.05) únicamente entre el tratamiento con CIDR nuevos (40 ± 10 h) y CIDR de segundo uso (31 ± 9 h). En las variables presencia de estro, porcentaje de gestación, porcentaje de fertilidad y tipo de parto no se obtuvieron diferencias significativas (P>0.05) entre tratamientos. La presencia de estro osciló entre 93 y 100 %, el valor promedio de gestación fue 80.8 %, 80.2 % para fertilidad y 1.26 para el índice de prolificidad. Los porcentajes de partos sencillos fueron mayores (P≤0.05) a los partos dobles en los cuatro tratamientos. Se concluye que el uso de CIDR en protocolos de 6 días permite que los dispositivos sean utilizados hasta por cuatro ocasiones con buenos resultados

Magnetic dispersive solid phase microextraction coupled with on-line chemical vapor generation method to extraction/preconcentration of mercury from environmental samples and determination by graphite furnace atomic absorption spectrometry.

Mercury (Hg) is classified as priority hazardous substances. Concentrations found in the aquatic environment are at trace levels as result of natural processes, such as erosion and volcanism, and anthropogenic discharges related mainly to industrial and mining activities. Mercury is one of the most potent neurotoxins known, showing a high number of adverse health effects in animals and humans. For this reason, a simple and rapid method for the determination and preconcentration of mercury in environmental waters is proposed. This work is based on magnetic dispersive solid phase microextraction (MDSPME) coupled with on-line chemical vapour generation (CVG). Graphite furnace atomic absorption spectrometry (GFAAS) was employed for the quantification of Hg. In the preconcentration step, a shell structured Fe3O4@graphene oxide was suspended in the ionic liquid carrier (1-n-butyl-3-metilimidazolium tetrafluoroborate [BMIM][BF4]), obtaining a stable colloidal suspension called ferrofluid. This sorbent possesses as large contact surface area and a high density of polar groups on its surface. The nanoparticles, when finely dispersed in the sample solution, result in almost complete extraction of Hg within a few seconds. All experimental and instrumental variables were optimized and the method was adequately validated by the analysis of certified reference materials of environmental waters. Acknowledgements The authors would like to thank Plan Propio “Proyecto Puente” de la Universidad de Málaga for financial support of this work.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

Solid sampling determination of ZnO nanoparticles in eyeshadows by graphite furnace atomic absorption spectrometry

The application of nanoparticles (NPs) in science and technology is a fast growing field. Therefore, reliable and straightforward analytical methods are required for their fast determination in different types of samples. In this work, a method that enables the determination of the average size of ZnO NPs, besides their concentration, discriminating them from ionic zinc, has been optimized. The method is based on solid sampling high-resolution continuum source electrothermal atomic absorption spectrometry (SS-HR-CS-GFAAS), and has been applied to determination and characterization of ZnO NPs in cosmetic samples. Recently, graphite furnace atomic absorption spectrometry has been introduced as a new tool to determine the size of nanoparticles by evaluation of the following parameters: atomization delay (tad) and atomization rate (kat). In this work both parameters (besides peak area) have been obtained from absorbance signals for a line of Zn with low sensitivity. Two multiple response surface designs have been used in order to optimize the adequate furnace program to achieve our aims. All the optimization experiments were performed using baby´s skin irritation protective cream. The optimized furnace program is shown in Table 1. Table 1. Optimized furnace program The size calibrations were performed against solid (powered) ZnO standards, from 50-nm to 500-nm sized nanoparticles. The correlation coefficients (R value) of the linear calibration were not worse than 0.9982. The optimized method was tested in other types of cosmetic samples such as eyeshadow samples with good results. The determination of the MNPs’ size was validated by transmission electron microscopy (TEM) and the Zn concentration in the solid samples was validated by atomic fluorescence spectroscopy (AFS). Acknowledgements (optional) [Garamond font, 10 points] The authors would like to thank Plan propio “Proyecto Puente” de la Universidad de Málaga for financial support of this work.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

Diseño del Modelo Navegacional para Sistemas de Tratamiento de Bibliotecas Digitales

Los sistemas de tratamiento de bibliotecas digitales nacen como sistemas complejos en los que se mezclan importantes requisitos de almacenamiento de información, debido a los múltiples medios que se usan en ellos, con grandes necesidades funcionales. Pero además en el entorno de las bibliotecas digitales se añaden unas necesidades, que son propias de las aplicaciones multimedia y páginas web, como son el uso de los enlaces y el ofrecer una atractiva interfaz de usuario. Estas nuevas necesidades se hacen patentes principalmente en la fase de diseño de la aplicación, puesto que es en ella donde se le añadirán a la aplicación. En este trabajo, se propone cómo se puede incorporar el diseño de los aspectos de navegación a una aplicación