Interactions between U(1)U(1) Cosmic Strings: An Analytical Study

We derive analytic expressions for the interaction energy between two general $U(1)$ cosmic strings as the function of their relative orientation and the ratio of the coupling constants in the model. The results are relevant to the statistic description of strings away from critical coupling and shed some light on the mechanisms involved in string formation and the evolution of string networks.Comment: 31 pages,REVTEX, Imperial/TP/93-94/3

Bacillus Calmette-Guérin-activated murine macrophages kill syngeneic melanoma cells under strict anaerobic conditions

We have studied the spontaneous killing of B5(59) melanoma cells by Bacillus Calmette-Guérin (BCG)-elicited macrophages under strictly anaerobic conditions to investigate the role of oxygen in macrophage-mediated cytotoxicity. The number of melanoma cells capable of forming colonies after aerobic or anaerobic incubation with BCG-macrophages was used as the index of cytotoxicity. The BCG-macrophages killed melanoma cells regardless of the amount of oxygen present. The killing observed was proportional to the ratio of effector cells added; a ratio of 25:1 effector to target cells was required to achieve nearly 90% cytotoxicity both aerobically and anaerobically. This cytotoxicity was not dependent on a diffusible macrophage product nor on alteration of the medium by macrophages, since tumor cells incubated in the same culture medium, but not in contact with a mixed population of tumor cells and macrophages, were not killed. These results also indicated that macrophage-mediated cytotoxicity was dependent on macrophage-tumor cell contact. The mechanism responsible for the oxygen-independent cytotoxicity is unknown at present

Tolerance to the Effects of Morphine on Intestinal Motility of Unanesthetized Dogs1

ABSTRACT Weisbrodt, Norma

Spinning particles in the vacuum C metric

The motion of a spinning test particle given by the Mathisson-Papapetrou equations is studied on an exterior vacuum C metric background spacetime describing the accelerated motion of a spherically symmetric gravitational source. We consider circular orbits of the particle around the direction of acceleration of the source. The symmetries of this configuration lead to the reduction of the differential equations of motion to algebraic relations. The spin supplementary conditions as well as the coupling between the spin of the particle and the acceleration of the source are discussed.Comment: IOP macros used, eps figures n.

Shotgun metagenomic analysis of microbial communities from the Loxahatchee nature preserve in the Florida Everglades.

BackgroundCurrently, much is unknown about the taxonomic diversity and the mechanisms of methane metabolism in the Florida Everglades ecosystem. The Loxahatchee National Wildlife Refuge is a section of the Florida Everglades that is almost entirely unstudied in regard to taxonomic profiling. This short report analyzes the metagenome of soil samples from this Refuge to investigate the predominant taxa, as well as the abundance of genes involved in environmentally significant metabolic pathways related to methane production (nitrogen fixation and dissimilatory sulfite reduction).MethodsShotgun metagenomic sequencing using the Illumina platform was performed on 17 soil samples from four different sites within the Loxahatchee National Wildlife Refuge, and underwent quality control, assembly, and annotation. The soil from each sample was tested for water content and concentrations of organic carbon and nitrogen.ResultsThe three most common phyla of bacteria for every site were Actinobacteria, Acidobacteria, and Proteobacteria; however, there was variation in relative phylum composition. The most common phylum of Archaea was Euryarchaeota for all sites. Alpha and beta diversity analyses indicated significant congruity in taxonomic diversity in most samples from Sites 1, 3, and 4 and negligible congruity between Site 2 and the other sites. Shotgun metagenomic sequencing revealed the presence of biogeochemical biomarkers of particular interest (e.g., mrcA, nifH, and dsrB) within the samples. The normalized abundances of mcrA, nifH, and dsrB exhibited a positive correlation with nitrogen concentration and water content, and a negative correlation with organic carbon concentration.ConclusionThis Everglades soil metagenomic study allowed examination of wetlands biological processes and showed expected correlations between measured organic constituents and prokaryotic gene frequency. Additionally, the taxonomic profile generated gives a basis for the diversity of prokaryotic microbial life throughout the Everglades

Phase Space Analysis of Quintessence Cosmologies with a Double Exponential Potential

We use phase space methods to investigate closed, flat, and open Friedmann-Robertson-Walker cosmologies with a scalar potential given by the sum of two exponential terms. The form of the potential is motivated by the dimensional reduction of M-theory with non-trivial four-form flux on a maximally symmetric internal space. To describe the asymptotic features of run-away solutions we introduce the concept of a `quasi fixed point.' We give the complete classification of solutions according to their late-time behavior (accelerating, decelerating, crunch) and the number of periods of accelerated expansion.Comment: 46 pages, 5 figures; v2: minor changes, references added; v3: title changed, refined classification of solutions, 3 references added, version which appeared in JCA

D-branes on general N=1 backgrounds: superpotentials and D-terms

We study the dynamics governing space-time filling D-branes on Type II flux backgrounds preserving four-dimensional N=1 supersymmetry. The four-dimensional superpotentials and D-terms are derived. The analysis is kept on completely general grounds thanks to the use of recently proposed generalized calibrations, which also allow one to show the direct link of the superpotentials and D-terms with BPS domain walls and cosmic strings respectively. In particular, our D-brane setting reproduces the tension of D-term strings found from purely four-dimensional analysis. The holomorphicity of the superpotentials is also studied and a moment map associated to the D-terms is proposed. Among different examples, we discuss an application to the study of D7-branes on SU(3)-structure backgrounds, which reproduces and generalizes some previous results.Comment: 50 pages; v2: table of contents, some clarifications and references added; v3: typos corrected and references adde

Cosmic Strings and Superstrings

Cosmic strings are predicted by many field-theory models, and may have been formed at a symmetry-breaking transition early in the history of the universe, such as that associated with grand unification. They could have important cosmological effects. Scenarios suggested by fundamental string theory or M-theory, in particular the popular idea of brane inflation, also strongly suggest the appearance of similar structures. Here we review the reasons for postulating the existence of cosmic strings or superstrings, the various possible ways in which they might be detected observationally, and the special features that might discriminate between ordinary cosmic strings and superstrings.Comment: Minor errors corrected and some references added, 34 pages, 6 figure