12,049 research outputs found

    Cosmic Ray Accelerators in the Large Magellanic Cloud

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    I point out a correlation between gamma-ray emissivity and the historical star formation rate in the Large Magellanic Cloud ~12.5 Myr ago. This correlation bolsters the view that CRs in the LMC are accelerated by conglomerations of supernova remnants: i.e. superbubbles and supergiant shells.Comment: Research Not

    A novel mode of capping protein-regulation by Twinfilin

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    Cellular actin assembly is controlled at the barbed ends of actin filaments, where capping protein (CP) limits polymerization. Twinfilin is a conserved in vivo binding partner of CP, yet the significance of this interaction has remained a mystery. Here, we discover that the C-terminal tail of Twinfilin harbors a CP-interacting (CPI) motif, identifying it as a novel CPI-motif protein. Twinfilin and the CPI-motif protein CARMIL have overlapping binding sites on CP. Further, Twinfilin binds competitively with CARMIL to CP, protecting CP from barbed-end displacement by CARMIL. Twinfilin also accelerates dissociation of the CP inhibitor V-1, restoring CP to an active capping state. Knockdowns of Twinfilin and CP each cause similar defects in cell morphology, and elevated Twinfilin expression rescues defects caused by CARMIL hyperactivity. Together, these observations define Twinfilin as the first \u27pro-capping\u27 ligand of CP and lead us to propose important revisions to our understanding of the CP regulatory cycle

    Estimating regional evapotranspiration from remotely sensed data by surface energy balance models

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    Spatial and temporal variations of surface radiative temperatures of the burned and unburned areas of the Konza tallgrass prairie were studied. The role of management practices, topographic conditions and the uncertainties associated with in situ or airborne surface temperature measurements were assessed. Evaluation of diurnal and seasonal spectral characteristics of the burned and unburned areas of the prairie was also made. This was accomplished based on the analysis of measured spectral reflectance of the grass canopies under field conditions, and modelling their spectral behavior using a one dimensional radiative transfer model

    Channelling of hydrothermal fluids during the accretion and evolution of the upper oceanic crust: Sr isotope evidence from ODP Hole 1256D

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    ODP Hole 1256D in the eastern equatorial Pacific is the first penetration of a complete section of fast spread ocean crust down to the dike-gabbro transition, and only the second borehole to sample in situ sheeted dikes after DSDP Hole 504B. Here a high spatial resolution record of whole rock and mineral strontium isotopic compositions from Site 1256 is combined with core observations and downhole wireline geophysical measurements to determine the extent of basalt-hydrothermal fluid reaction and to identify fluid pathways at different levels in the upper ocean crust.The volcanic sequence at Site 1256 is dominated by sheet and massive lava flows but the Sr isotope profile shows only limited exchange with seawater. However, the upper margins of two anomalously thick (>25 m) massive flow sequences are strongly hydrothermally altered with elevated Sr isotope ratios and appear to be conduits of lateral low-temperature off-axis fluid flow. Elsewhere in the lavas, high 87Sr/86Sr are restricted to breccia horizons. Mineralised hyaloclastic breccias in the Lava-Dike Transition are strongly altered to Mg-saponite, silica and pyrite, indicating alteration by mixed seawater and cooled hydrothermal fluids. In the Sheeted Dike Complex 87Sr/86Sr ratios are pervasively shifted towards hydrothermal fluid values (~0.705). Dike chilled margins display secondary mineral assemblages formed during both axial recharge and discharge and have higher 87Sr/86Sr than dike cores, indicating preferential fluid flow along dike margins. Localised increases in 87Sr/86Sr in the Dike-Gabbro Transition indicates the channelling of fluids along the sub-horizontal intrusive boundaries of the 25 to 50 m-thick gabbroic intrusions, with only minor increases in 87Sr/86Sr within the cores of the gabbro bodies.When compared to the pillow lava-dominated section from Hole 504B, the Sr isotope measurements from Site 1256 suggest that the extent of hydrothermal circulation in the upper ocean crust may be strongly dependent on the eruption style. Sheet and massive flow dominated lava sequences typical of fast spreading ridges may experience relatively restricted circulation, but there may be much more widespread circulation through pillow lava-dominated sections. In addition, the Hole 1256D sheeted dikes display a much greater extent of Sr-isotopic exchange compared to dikes from Hole 504B. Because seawater-derived hydrothermal fluids must transit the dikes during their evolution to black smoker-type fluids, the different Sr-isotope profiles for Holes 504B and 1256D suggest there are significant variations in mid-ocean ridge hydrothermal systems at fast and intermediate spreading ridges, which may impact geochemical cycles of elements mobilised by fluid-rock exchange at different temperatures

    Non-equilibrium dynamics in quantum field theory at high density: the tsunami

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    The dynamics of a dense relativistic quantum fluid out of thermodynamic equilibrium is studied in the framework of the Phi^4 scalar field theory in the large N limit. The time evolution of a particle distribution in momentum space (the tsunami) is computed. The effective mass felt by the particles in such a high density medium equals the tree level mass plus the expectation value of the squared field. The case of negative tree level squared mass is particularly interesting. In such case dynamical symmetry restoration as well as dynamical symmetry breaking can happen. Furthermore, the symmetry may stay broken with vanishing asymptotic squared mass showing the presence of out of equilibrium Goldstone bosons. We study these phenomena and identify the set of initial conditions that lead to each case. We compute the equation of state which turns to depend on the initial state. Although the system does not thermalize, the equation of state for asymptotically broken symmetry is of radiation type. We compute the correlation functions at equal times. The two point correlator for late times is the sum of different terms. One stems from the initial particle distribution. Another term accounts for the out of equilibrium Goldstone bosons created by spinodal unstabilities when the symmetry is asymptotically broken.Both terms are of the order of the inverse of the coupling for distances where causal signals can connect the two points. The contribution of the out of equilibrium Goldstones exhibits scaling behaviour in a generalized sense.Comment: LaTex, 49 pages, 15 .ps figure

    Prenatal development is linked to bronchial reactivity: epidemiological and animal model evidence

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    Chronic cardiorespiratory disease is associated with low birthweight suggesting the importance of the developmental environment. Prenatal factors affecting fetal growth are believed important, but the underlying mechanisms are unknown. The influence of developmental programming on bronchial hyperreactivity is investigated in an animal model and evidence for comparable associations is sought in humans. Pregnant Wistar rats were fed either control or protein-restricted diets throughout pregnancy. Bronchoconstrictor responses were recorded from offspring bronchial segments. Morphometric analysis of paraffin-embedded lung sections was conducted. In a human mother-child cohort ultrasound measurements of fetal growth were related to bronchial hyperreactivity, measured at age six years using methacholine. Protein-restricted rats' offspring demonstrated greater bronchoconstriction than controls. Airway structure was not altered. Children with lesser abdominal circumference growth during 11-19 weeks' gestation had greater bronchial hyperreactivity than those with more rapid abdominal growth. Imbalanced maternal nutrition during pregnancy results in offspring bronchial hyperreactivity. Prenatal environmental influences might play a comparable role in humans
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