1,132 research outputs found
New Measurements of the Particle Size Distribution of Apollo 11 Lunar Soil 10084
We have initiated a major new program to determine the grain size distribution of nearly all lunar soils collected in the Apollo program. Following the return of Apollo soil and core samples, a number of investigators including our own group performed grain size distribution studies and published the results [1-11]. Nearly all of these studies were done by sieving the samples, usually with a working fluid such as Freon(TradeMark) or water. We have measured the particle size distribution of lunar soil 10084,2005 in water, using a Microtrac(TradeMark) laser diffraction instrument. Details of our own sieving technique and protocol (also used in [11]). are given in [4]. While sieving usually produces accurate and reproducible results, it has disadvantages. It is very labor intensive and requires hours to days to perform properly. Even using automated sieve shaking devices, four or five days may be needed to sieve each sample, although multiple sieve stacks increases productivity. Second, sieving is subject to loss of grains through handling and weighing operations, and these losses are concentrated in the finest grain sizes. Loss from handling becomes a more acute problem when smaller amounts of material are used. While we were able to quantitatively sieve into 6 or 8 size fractions using starting soil masses as low as 50mg, attrition and handling problems limit the practicality of sieving smaller amounts. Third, sieving below 10 or 20microns is not practical because of the problems of grain loss, and smaller grains sticking to coarser grains. Sieving is completely impractical below about 5- 10microns. Consequently, sieving gives no information on the size distribution below approx.10 microns which includes the important submicrometer and nanoparticle size ranges. Finally, sieving creates a limited number of size bins and may therefore miss fine structure of the distribution which would be revealed by other methods that produce many smaller size bins
Preliminary Regional Analysis of the Kaguya Lunar Radar Sounder (LRS) Data through Eastern Mare Imbrium
The Lunar Radar Sounder (LRS) experiment on board the Kaguya spacecraft is observing the subsurface structure of the Moon, using ground-penetrating radar operating in the frequency range of 5 MHz [1]. Because LRS data provides in-formation about lunar features below the surface, it allows us to improve our understanding of the processes that formed the Moon, and the post-formation changes that have occurred (such as basin formation and volcanism). We look at a swath of preliminary LRS data, that spans from 7 to 72 N, and from 2 to 10 W, passing through the eastern portion of Mare Imbrium (Figure 1). Using software, designed for the mineral exploration industry, we produce a preliminary, coarse 3D model, showing the regional structure beneath the study area. Future research will involve smaller subsets of the data in regions of interest, where finer structures, such as those identified in [2], can be studied
Assessment of measures of adiposity that correlate with blood pressure among hypertensive Africans
Background: Studies differ on which anthropometric measure of adiposity shows good correlation with cardiovascular diseases. In this study, we evaluated the effects of common epidemiological measures of adiposity as a correlate of elevated blood pressure in an African population.Methodology: The study was carried out between June 2009 and December 2011 at the medical out-patient department of a tertiary healthcare center in Nigeria. Correlation analysis was used to assess the relationship between blood pressure and body mass index (BMI), waist to height ratio (WHtR), and waist circumference (WC).Results: A total of 1,416 Hypertensives comprising 1090 (77%) adult females recruited over two and half years. Women were significantly older (49.2±8.1 vs. 48.0±10.0 years, p=0.039) and shorter (1.6±6.3 vs 1.7±6.8 meters, p<0.0001) when compared with men. Blood pressure parameters were comparable between women and men. Approximately 1 out of 5 participants had good blood pressure control with no gender difference. Anthropometric measurements showed that 446(32%) were overweight, 404(29%) obese and 40(3%) were morbidly obese. Compared with their male counterparts, females were significantly more likely to be obese (P<0.0001). Similarly, 51.6% of the subjects had abdominal obesity, with female preponderance (P<0.0001). Likewise, a greater proportion of women had substantially higher measured waist circumference risk. Compared with other measures of adiposity, body mass index correlated best with diastolic blood pressure in both gender (P< 0.05).Conclusion: This study adds to the evidence that obesity is a major cardiovascular risk factor. BMI, as a measure of adiposity, was found to correlate best with blood pressure. These findings support other observations in other populations that BMI rather than waist to height ratio (WHtR), and waist circumference (WC) is a better correlate of hypertension
Correlation Entropy of an Interacting Quantum Field and H-theorem for the O(N) Model
Following the paradigm of Boltzmann-BBGKY we propose a correlation entropy
(of the nth order) for an interacting quantum field, obtained by `slaving'
(truncation with causal factorization) of the higher (n+1 th) order correlation
functions in the Schwinger-Dyson system of equations. This renders an otherwise
closed system effectively open where dissipation arises. The concept of
correlation entropy is useful for addressing issues related to thermalization.
As a small yet important step in that direction we prove an H-theorem for the
correlation entropy of a quantum mechanical O(N) model with a Closed Time Path
Two Particle Irreducible Effective Action at the level of Next-to-Leading-Order
large N approximation. This model may be regarded as a field theory in
space dimensions.Comment: 22 page
Magnetotransport Mechanisms in Strongly Underdoped YBa_2Cu_3O_x Single Crystals
We report magnetoresistivity measurements on strongly underdoped YBa_2Cu_3O_x
(x=6.25, 6.36) single crystals in applied magnetic fields H || c-axis. We
identify two different contributions to both in-plane and out-of-plane
magnetoresistivities. The first contribution has the same sign as the
temperature coefficient of the resistivity \partial ln(\rho_i)/\partial T
(i={c,ab}). This contribution reflects the incoherent nature of the
out-of-plane transport. The second contribution is positive, quadratic in
field, with an onset temperature that correlates to the antiferromagnetic
ordering.Comment: 4 pages, 3 figure
Human papillomavirus and abnormal cervical lesions among HIV-infected women in HIV-discordant couples from Kenya
Objective HIV infection increases the risk of high-grade cervical neoplasia and invasive cervical carcinoma. The study addresses the limited data describing human papillomavirus (HPV) infection and cervical neoplasia among HIV-infected women in HIV-discordant relationships in sub-Saharan Africa, which is needed to inform screening strategies. Methods A cross-sectional study of HIV-infected women with HIV-uninfected partners was conducted to determine the distribution of type-specific HPV infection and cervical cytology. This study was nested in a prospective cohort recruited between September 2007 and December 2009 in Nairobi, Kenya. Cervical cells for HPV DNA testing and conventional cervical cytology were collected. HPV types were detected and genotyped by Roche Linear Array PCR assay. Results Among 283 women, the overall HPV prevalence was 62%, and 132 (47%) had ≥1 high-risk (HR)-HPV genotype. Of 268 women with cervical cytology results, 18 (7%) had high-grade cervical lesions or more severe by cytology, of whom 16 (89%) were HR-HPV-positive compared with 82 (41%) of 199 women with normal cytology (p<0.001). The most common HR-HPV types in women with a high-grade lesion or more severe by cytology were HPV-52 (44%), HPV-31 (22%), HPV-35 (22%), HPV-51 (22%) and HPV-58 (22%). HR-HPV genotypes HPV-16 or HPV-18 were found in 17% of women with high-grade lesions or more severe. HR-HPV screening applied in this population would detect 89% of those with a high-grade lesion or more severe, while 44% of women with normal or low-grade cytology would screen positive. Conclusion HR-HPV prevalence was high in this population of HIV-infected women with an uninfected partner. Choice of screening for all HR genotypes versus a subset of HR genotypes in these HIV-infected women will strongly affect the performance of an HPV screening strategy relative to cytological screening. Regional and subpopulation differences in HR-HPV genotype distributions could affect screening test performance
From QFT to DCC
A quantum field theoretical model for the dynamics of the disoriented chiral
condensate is presented. A unified approach to relate the quantum field theory
directly to the formation, decay and signals of the DCC and its evolution is
taken. We use a background field analysis of the O(4) sigma model keeping
one-loop quantum corrections (quadratic order in the fluctuations). An
evolution of the quantum fluctuations in an external, expanding metric which
simulates the expansion of the plasma, is carried out. We examine, in detail,
the amplification of the low momentum pion modes with two competing effects,
the expansion rate of the plasma and the transition rate of the vacuum
configuration from a metastable state into a stable state.We show the effect of
DCC formation on the multiplicity distributions and the Bose-Einstein
correlations.Comment: 34 pages, 10 figure
Current-induced cooling phenomenon in a two-dimensional electron gas under a magnetic field
We investigate the spatial distribution of temperature induced by a dc
current in a two-dimensional electron gas (2DEG) subjected to a perpendicular
magnetic field. We numerically calculate the distributions of the electrostatic
potential phi and the temperature T in a 2DEG enclosed in a square area
surrounded by insulated-adiabatic (top and bottom) and isopotential-isothermal
(left and right) boundaries (with phi_{left} < phi_{right} and T_{left}
=T_{right}), using a pair of nonlinear Poisson equations (for phi and T) that
fully take into account thermoelectric and thermomagnetic phenomena, including
the Hall, Nernst, Ettingshausen, and Righi-Leduc effects. We find that, in the
vicinity of the left-bottom corner, the temperature becomes lower than the
fixed boundary temperature, contrary to the naive expectation that the
temperature is raised by the prevalent Joule heating effect. The cooling is
attributed to the Ettingshausen effect at the bottom adiabatic boundary, which
pumps up the heat away from the bottom boundary. In order to keep the adiabatic
condition, downward temperature gradient, hence the cooled area, is developed
near the boundary, with the resulting thermal diffusion compensating the upward
heat current due to the Ettingshausen effect.Comment: 25 pages, 7 figure
Mutations of the BRAF gene in human cancer
Cancers arise owing to the accumulation of mutations in critical genes that alter normal programmes of cell proliferation, differentiation and death. As the first stage of a systematic genome-wide screen for these genes, we have prioritized for analysis signalling pathways in which at least one gene is mutated in human cancer. The RAS RAF MEK ERK MAP kinase pathway mediates cellular responses to growth signals. RAS is mutated to an oncogenic form in about 15% of human cancer. The three RAF genes code for cytoplasmic serine/threonine kinases that are regulated by binding RAS. Here we report BRAF somatic missense mutations in 66% of malignant melanomas and at lower frequency in a wide range of human cancers. All mutations are within the kinase domain, with a single substitution (V599E) accounting for 80%. Mutated BRAF proteins have elevated kinase activity and are transforming in NIH3T3 cells. Furthermore, RAS function is not required for the growth of cancer cell lines with the V599E mutation. As BRAF is a serine/threonine kinase that is commonly activated by somatic point mutation in human cancer, it may provide new therapeutic opportunities in malignant melanoma
BEC Collapse and Dynamical Squeezing of Vacuum Fluctuations
We analyze the phenomena of Bose Novae, as described by Donley et al [Nature
412, 295 (2001)], by focusing on the behavior of excitations or fluctuations
above the condensate, as driven by the dynamics of the condensate (rather than
the dynamics of the condensate alone or the kinetics of the atoms). The
dynamics of the condensate squeezes and amplifies the quantum excitations,
mixing the positive and negative frequency components of their wave functions
thereby creating particles which appear as bursts and jets. By analyzing the
changing amplitude and particle content of these excitations, our simple
physical picture (based on a test field approximation) explains well the
overall features of the Bose Novae phenomena and provide excellent quantitative
fits with experimental data on several aspects, such as the scaling behavior of
the collapse time and the amount of particles in the jet. The predictions of
the bursts at this level of approximation is less than satisfactory but may be
improved on by including the backreaction of the excitations on the condensate.
The mechanism behind the dominant effect -- parametric amplification of vacuum
fluctuations and freezing of modes outside of horizon -- is similar to that of
cosmological particle creation and structure formation in a rapid quench (which
is fundamentally different from Hawking radiation in black holes). This shows
that BEC dynamics is a promising venue for doing `laboratory cosmology'.Comment: Latex 36 pages, 6 figure
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