1,399 research outputs found
Ranking Templates for Linear Loops
We present a new method for the constraint-based synthesis of termination
arguments for linear loop programs based on linear ranking templates. Linear
ranking templates are parametrized, well-founded relations such that an
assignment to the parameters gives rise to a ranking function. This approach
generalizes existing methods and enables us to use templates for many different
ranking functions with affine-linear components. We discuss templates for
multiphase, piecewise, and lexicographic ranking functions. Because these
ranking templates require both strict and non-strict inequalities, we use
Motzkin's Transposition Theorem instead of Farkas Lemma to transform the
generated -constraint into an -constraint.Comment: TACAS 201
Long range absorption in the scattering of 6He on 208Pb and 197Au at 27 MeV
Quasi-elastic scattering of 6He at E_lab=27 MeV from 197Au has been measured
in the angular range of 6-72 degrees in the laboratory system employing LEDA
and LAMP detection systems. These data, along with previously analysed data of
6He + 208Pb at the same energy, are analyzed using Optical Model calculations.
The role of Coulomb dipole polarizability has been investigated. Large
imaginary diffuseness parameters are required to fit the data. This result is
an evidence for long range absorption mechanisms in 6He induced reactions.Comment: 10 pages, 10 figures, minor corrections. To appear in Nucl. Phys.
Proving Termination Starting from the End
We present a novel technique for proving program termination which introduces
a new dimension of modularity. Existing techniques use the program to
incrementally construct a termination proof. While the proof keeps changing,
the program remains the same. Our technique goes a step further. We show how to
use the current partial proof to partition the transition relation into those
behaviors known to be terminating from the current proof, and those whose
status (terminating or not) is not known yet. This partition enables a new and
unexplored dimension of incremental reasoning on the program side. In addition,
we show that our approach naturally applies to conditional termination which
searches for a precondition ensuring termination. We further report on a
prototype implementation that advances the state-of-the-art on the grounds of
termination and conditional termination.Comment: 16 page
Disease-specific, neurosphere-derived cells as models for brain disorders
There is a pressing need for patient-derived cell models of brain diseases that are relevant and robust enough to produce the large quantities of cells required for molecular and functional analyses. We describe here a new cell model based on patient-derived cells from the human olfactory mucosa, the organ of smell, which regenerates throughout life from neural stem cells. Olfactory mucosa biopsies were obtained from healthy controls and patients with either schizophrenia, a neurodevelopmental psychiatric disorder, or Parkinson's disease, a neurodegenerative disease. Biopsies were dissociated and grown as neurospheres in defined medium. Neurosphere-derived cell lines were grown in serum-containing medium as adherent monolayers and stored frozen. By comparing 42 patient and control cell lines we demonstrated significant disease-specific alterations in gene expression, protein expression and cell function, including dysregulated neurodevelopmental pathways in schizophrenia and dysregulated mitochondrial function, oxidative stress and xenobiotic metabolism in Parkinson's disease. The study has identified new candidate genes and cell pathways for future investigation. Fibroblasts from schizophrenia patients did not show these differences. Olfactory neurosphere-derived cells have many advantages over embryonic stem cells and induced pluripotent stem cells as models for brain diseases. They do not require genetic reprogramming and they can be obtained from adults with complex genetic diseases. They will be useful for understanding disease aetiology, for diagnostics and for drug discovery
A low-voltage retarding-field Mott polarimeter for photocathode characterization
Nuclear physics experiments at Thomas Jefferson National Accelerator
Facility's CEBAF rely on high polarization electron beams. We describe a
recently commissioned system for prequalifying and studying photocathodes for
CEBAF with a load-locked, low-voltage polarized electron source coupled to a
compact retarding-field Mott polarimeter. The polarimeter uses simplified
electrode structures and operates from 5 to 30 kV. The effective Sherman
function for this device has been calibrated by comparison with the CEBAF 5 MeV
Mott polarimeter. For elastic scattering from a thick gold target at 20 keV,
the effective Sherman function is 0.201(5). Its maximum efficiency at 20 keV,
defined as the detected count rate divided by the incident particle current, is
5.4(2) x 10-4, yielding a figure-of-merit, or analyzing power squared times
efficiency, of 1.0(1) x 10-5. The operating parameters of this new polarimeter
design are compared to previously published data for other compact Mott
polarimeters of the retarding-field type.Comment: 9 figure
A Graph Theoretic Approach for Object Shape Representation in Compositional Hierarchies Using a Hybrid Generative-Descriptive Model
A graph theoretic approach is proposed for object shape representation in a
hierarchical compositional architecture called Compositional Hierarchy of Parts
(CHOP). In the proposed approach, vocabulary learning is performed using a
hybrid generative-descriptive model. First, statistical relationships between
parts are learned using a Minimum Conditional Entropy Clustering algorithm.
Then, selection of descriptive parts is defined as a frequent subgraph
discovery problem, and solved using a Minimum Description Length (MDL)
principle. Finally, part compositions are constructed by compressing the
internal data representation with discovered substructures. Shape
representation and computational complexity properties of the proposed approach
and algorithms are examined using six benchmark two-dimensional shape image
datasets. Experiments show that CHOP can employ part shareability and indexing
mechanisms for fast inference of part compositions using learned shape
vocabularies. Additionally, CHOP provides better shape retrieval performance
than the state-of-the-art shape retrieval methods.Comment: Paper : 17 pages. 13th European Conference on Computer Vision (ECCV
2014), Zurich, Switzerland, September 6-12, 2014, Proceedings, Part III, pp
566-581. Supplementary material can be downloaded from
http://link.springer.com/content/esm/chp:10.1007/978-3-319-10578-9_37/file/MediaObjects/978-3-319-10578-9_37_MOESM1_ESM.pd
Quantum Anti-Zeno Effect
We demonstrate that near threshold decay processes may be accelerated by
repeated measurements. Examples include near threshold photodetachment of an
electron from a negative ion, and spontaneous emission in a cavity close to the
cutoff frequency, or in a photon band gap material.Comment: 4 pages, 3 figure
Hoop conjecture for colliding black holes : non-time-symmetric initial data
The hoop conjecture is well confirmed in momentarily static spaces, but it
has not been investigated systematically for the system with relativistic
motion. To confirm the hoop conjecture for non-time-symmetric initial data, we
consider the initial data of two colliding black holes with momentum and search
an apparent horizon that encloses two black holes. In testing the hoop
conjecture, we use two definitions of gravitational mass : one is the ADM mass
and the other is the quasi-local mass defined by Hawking. Although both
definitions of gravitational mass give fairly consistent picture of the hoop
conjecture, the hoop conjecture with the Hawking mass can judge the existence
of an apparent horizon for wider range of parameters of the initial data
compared to the ADM mass.Comment: 15pages, 4 figure
The Lazarus project: A pragmatic approach to binary black hole evolutions
We present a detailed description of techniques developed to combine 3D
numerical simulations and, subsequently, a single black hole close-limit
approximation. This method has made it possible to compute the first complete
waveforms covering the post-orbital dynamics of a binary black hole system with
the numerical simulation covering the essential non-linear interaction before
the close limit becomes applicable for the late time dynamics. To determine
when close-limit perturbation theory is applicable we apply a combination of
invariant a priori estimates and a posteriori consistency checks of the
robustness of our results against exchange of linear and non-linear treatments
near the interface. Once the numerically modeled binary system reaches a regime
that can be treated as perturbations of the Kerr spacetime, we must
approximately relate the numerical coordinates to the perturbative background
coordinates. We also perform a rotation of a numerically defined tetrad to
asymptotically reproduce the tetrad required in the perturbative treatment. We
can then produce numerical Cauchy data for the close-limit evolution in the
form of the Weyl scalar and its time derivative
with both objects being first order coordinate and tetrad invariant. The
Teukolsky equation in Boyer-Lindquist coordinates is adopted to further
continue the evolution. To illustrate the application of these techniques we
evolve a single Kerr hole and compute the spurious radiation as a measure of
the error of the whole procedure. We also briefly discuss the extension of the
project to make use of improved full numerical evolutions and outline the
approach to a full understanding of astrophysical black hole binary systems
which we can now pursue.Comment: New typos found in the version appeared in PRD. (Mostly found and
collected by Bernard Kelly
Impact of densitized lapse slicings on evolutions of a wobbling black hole
We present long-term stable and second-order convergent evolutions of an
excised wobbling black hole. Our results clearly demonstrate that the use of a
densitized lapse function extends the lifetime of simulations dramatically. We
also show the improvement in the stability of single static black holes when an
algebraic densitized lapse condition is applied. In addition, we introduce a
computationally inexpensive approach for tracking the location of the
singularity suitable for mildly distorted black holes. The method is based on
investigating the fall-off behavior and asymmetry of appropriate grid
variables. This simple tracking method allows one to adjust the location of the
excision region to follow the coordinate motion of the singularity.Comment: 10 pages, 8 figure
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