3 research outputs found
Prevention of congenital toxoplasmosis in the Netherlands
In this thesis the results of a large-scale study of preventive measures against
toxoplasma infections in pregnant women are reported. Literature on Toxoplasma gondii, toxoplasma infections and toxoplasmosis
is discussed in chapter 1. Special attention is directed toward the epidemiological
aspects as they relate to the possibilities of preventing congenital
toxoplasmosis. The historical background is presented as an introduction
to the actual study. The initial aim of separate evaluation of primary and
secondary prevention had to be abandoned due to various circumstances.
As a result, the study was finally designed to evaluate the simultaneous
application of both primary and secondary preventive measures in order
to be able to establish guidelines and prerequisites for a future national
preventive programmeSince no effective therapy is available to prevent manifestations of congenital
toxoplasmosis, prevention is the strategy par excellence to control congenital
toxoplasmosis. The World Health Organization in Europe recommended
that all countries consider the possibilities of a preventive programme; the
programmes in France and Austria were cited as examples of successful
disease controL At about the same time the Health Council in the Netherlands
recommended a trial study. In the study described here both primary and
secondary prevention were applied: repeated serological control of initially
seronegative women allowed assessment of the incidence of primary infections
during pregnancy when primary preventive measures were emphasized. In
this chapter different strategies to prevent congenital toxoplasmosis in the
Netherlands will be discusse