Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery

Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics. The ability to incorporate drugs into nanoparticles offers a new prototype in drug delivery thus realizing the dual goal of both controlled release and site-specific drug delivery. Drug delivery to the skin is widely used for local and systemic delivery and has potential to be improved by application of nanoparticulate formulations. If investigated appropriately, solid lipid nanoparticles may open new opportunities in therapy of complex diseases which is difficult to treat

Thermal analysis of a mobile lunar laboratory

Thermodynamic analysis and Fortran IV program for calculating time dependent internal atmospheric temperature within Mola

Book Review: Oxford Bibliographies: Hinduism and Christianity

Christopher R. Conway\u27s review of Oxford Bibliographies: Hinduism and Christianity, edited by Chad Bauman, Arun Jones, Brian Pennington, Joseph Prabhakar Dayam, and Michelle Voss Roberts

Reply to Comments of Bassi, Ghirardi, and Tumulka on the Free Will Theorem

We show that the authors in the title have erred in claiming that our axiom FIN is false by conflating it with Bell locality. We also argue that the predictions of quantum mechanics, and in particular EPR, are fully Lorentz invariant, whereas the Free Will Theorem shows that theories with a mechanism of reduction, such as GRW, cannot be made fully invariant.Comment: We sharpen our theorem by replacing axiom FIN by a weaker axiom MIN to answer the above authors' objection

Guidelines for testing and release procedures

Guidelines and procedures are recommended for the testing and release of the types of computer software efforts commonly performed at NASA/Ames Research Center. All recommendations are based on the premise that testing and release activities must be specifically selected for the environment, size, and purpose of each individual software project. Guidelines are presented for building a Test Plan and using formal Test Plan and Test Care Inspections on it. Frequent references are made to NASA/Ames Guidelines for Software Inspections. Guidelines are presented for selecting an Overall Test Approach and for each of the four main phases of testing: (1) Unit Testing of Components, (2) Integration Testing of Components, (3) System Integration Testing, and (4) Acceptance Testing. Tools used for testing are listed, including those available from operating systems used at Ames, specialized tools which can be developed, unit test drivers, stub module generators, and the use of format test reporting schemes

On the growth rate of 1324-avoiding permutations

We give an improved algorithm for counting the number of $1324$-avoiding permutations, resulting in 5 further terms of the generating function. We analyse the known coefficients and find compelling evidence that unlike other classical length-4 pattern-avoiding permutations, the generating function in this case does not have an algebraic singularity. Rather, the number of 1324-avoiding permutations of length $n$ behaves as $$B\cdot \mu^n \cdot \mu_1^{n^{\sigma}} \cdot n^g.$$ We estimate $\mu=11.60 \pm 0.01,$ $\sigma=1/2,$ $\mu_1 = 0.0398 \pm 0.0010,$ $g = -1.1 \pm 0.2$ and $B =9.5 \pm 1.0.$Comment: 20 pages, 10 figure