Perspectives: The Lab of the Future

A discussion of technology needs, and possible technology organization, to meet Lab of the Future needs for research areas in general, and Chemistry Labs in particular

Estimating abundance of Galliformes: tools and application

A large number of techniques are available for assessing populations of vertebrates. However, application of many of those techniques to Galliformes is hampered by a variety of constraints. These problems are often magnified by poor understanding of the biology of many species of concern, and an absence of valid estimates of abundance and demographic parameters. Researchers interested in developing estimates of Galliformes populations must address a number of key issues before collecting field data, to avoid biases in the resulting population estimates. General guidance exists for the identification of appropriate population estimation techniques, and a dichotomous key has been developed for abundance estimation of other vertebrates, such as mammals. First, we review some of the basic principles of abundance estimation, with the goal of identifying sources of bias, and avoiding these in field surveys. We then develop specific guidelines for Galliformes, and a key to abundance estimation for field researchers. Based on our knowledge of the general biology of Galliformes, the most applicable techniques for estimating abundance are based on variations of distance sampling techniques, mark-resighting techniques, and removal techniques. Use of indices should be considered only when more quantitative analyses are logistically or biologically impossible. However, their use can be made more valuable by employing double sampling or other methods that directly link indices to unbiased estimates of abundance

Data Presentation and Visualization (DPV) Interface Control Document

Data Presentation and Visualization (DPV) is a subset of the modeling and simulation (M&S) capabilities at Kennedy Space Center (KSC) that endeavors to address the challenges of how to present and share simulation output for analysts, stakeholders, decision makers, and other interested parties. DPV activities focus on the development and provision of visualization tools to meet the objectives identified above, as well as providing supporting tools and capabilities required to make its visualization products available and accessible across NASA

Distributed Observer Network (DON), Version 3.0, User's Guide

The Distributed Observer Network (DON) is a data presentation tool developed by the National Aeronautics and Space Administration (NASA) to distribute and publish simulation results. Leveraging the display capabilities inherent in modern gaming technology, DON places users in a fully navigable 3-D environment containing graphical models and allows the users to observe how those models evolve and interact over time in a given scenario. Each scenario is driven with data that has been generated by authoritative NASA simulation tools and exported in accordance with a published data interface specification. This decoupling of the data from the source tool enables DON to faithfully display a simulator's results and ensure that every simulation stakeholder will view the exact same information every time

Play Nice Across Time Space

Lecture is an overview of Simulation technologies, methods and practices, as applied to current and past NASA programs. Focus is on sharing experience and the overall benefits to programs and projects of having appropriate simulation and analysis capabilities available at the correct point in a system lifecycle

Landscape Features Affecting Northern Bobwhite Predator-Specific Nest Failures in Southeastern USA

Nest predation is a critical component in avian productivity and typically is the leading cause of nest failure for most birds. Several landscape features are thought to drive the behavioral interaction between northern bobwhite (Colinus virginianus; e.g., nest placement) and their predators (e.g., search methods for food acquisition). In order to understand habitat characteristics influencing predation, we studied bobwhite nests using 24-hour near-infrared video cameras. We monitored 675 bobwhite nests with cameras on 3 properties in northern Florida and southern Georgia, USA, during 2000–2006. To test the association between nest failures and specific failure causes with landscape structure, we calculated a suite of landscape metrics and examined these at 3 spatial scales (3.1 ha, 19.6 ha, and 50.3 ha). We found increased probability of nest success with greater proportions of, and proximity to, fallow and annually disked fields at larger scales (50.3 ha), but we found no landscape metrics to be important predictors of bobwhite nest failures at small scales (,20 ha). Fallow and disked fields may provide alternative prey items (e.g., rodents) important in buffering nest predation. Relative to meso-mammal predation, we observed increases in proportion of the landscape in field to be related to lower incidental nest failures at the smallest scale (3.1 ha). Nests closer to feed lines were more likely depredated by meso-mammals than ants at the 2 larger spatial scales. Interestingly, the fate of a nest was independent of the fate of neighboring nests, suggesting bobwhite nest predation may be primarily incidental

Drug-like antagonists of P2Y receptors — from lead identification to drug development

P2Y receptors are expressed in virtually all cells and tissue types and mediate an astonishing array of biological functions, including platelet aggregation, smooth muscle cell proliferation, and immune regulation. The P2Y receptors belong to the G protein-coupled receptor superfamily and are composed of eight members encoded by distinct genes that can be subdivided into two groups on the basis of their coupling to specific G-proteins. Extensive research has been undertaken to find modulators of P2Y receptors, although to date only a limited number of small-molecule P2Y receptor antagonists have been approved by drug/medicines agencies. This Perspective reviews the known P2Y receptor antagonists, highlighting oral drug-like receptor antagonists, and considers future opportunities for the development of small molecules for clinical evaluation

Landscape Features Affecting Northern Bobwhite Predator-Specific Nest Failures in Southeastern USA

Nest predation is a critical component in avian productivity and typically is the leading cause of nest failure for most birds. Several landscape features are thought to drive the behavioral interaction between northern bobwhite (Colinus virginianus; e.g., nest placement) and their predators (e.g., search methods for food acquisition). In order to understand habitat characteristics influencing predation, we studied bobwhite nests using 24-hour near-infrared video cameras. We monitored 675 bobwhite nests with cameras on 3 properties in northern Florida and southern Georgia, USA, during 2000–2006. To test the association between nest failures and specific failure causes with landscape structure, we calculated a suite of landscape metrics and examined these at 3 spatial scales (3.1 ha, 19.6 ha, and 50.3 ha). We found increased probability of nest success with greater proportions of, and proximity to, fallow and annually disked fields at larger scales (50.3 ha), but we found no landscape metrics to be important predictors of bobwhite nest failures at small scales (\u3c20 \u3eha). Fallow and disked fields may provide alternative prey items (e.g., rodents) important in buffering nest predation. Relative to meso-mammal predation, we observed increases in proportion of the landscape in field to be related to lower incidental nest failures at the smallest scale (3.1 ha). Nests closer to feed lines were more likely depredated by meso-mammals than ants at the 2 larger spatial scales. Interestingly, the fate of a nest was independent of the fate of neighboring nests, suggesting bobwhite nest predation may be primarily incidental

High flux cold Rubidium atomic beam for strongly coupled Cavity QED

This paper presents a setup capable of producing a high-flux continuous beam of cold rubidium atoms for cavity QED experiments in the regime of strong coupling. A 2 $D^+$ MOT, loaded by rubidium getters in a dry film coated vapor cell, fed a secondary moving-molasses MOT (MM-MOT) at a rate of 1.5 x $10^{10}$ atoms/sec. The MM-MOT provided a continuous beam with tunable velocity. This beam was then directed through the waist of a 280 $\mu$m cavity resulting in a Rabi splitting of more than +/- 10 MHz. The presence of sufficient number of atoms in the cavity mode also enabled splitting in the polarization perpendicular to the input. The cavity was in the strong coupling regime, with parameters (g, $\kappa$, $\gamma$)/2$\pi$ equal to (7, 3, 6)/ 2$\pi$ MHz.Comment: Journal pape