Rejecting Federal Preference: Why Courts Should Not Exempt Fannie Mae and Freddie Mac Properties from Cities’ Vacant Property Registration Ordinances

This Note discusses the recent trend in local vacant property registration ordinances. In essence, these ordinances have become increasingly popular since the burst of the housing bubble, as they require either homeowners or their mortgage lenders to register property upon abandonment. Specifically, this Note argues that properties held by Fannie Mae and Freddie Mac should not be exempted from the control of the ordinances, as such a large exemption will likely inhibit cities’ abilities to maintain abandoned property

Open Letter In Support of the Digital Humanities Studio Space at Butler Library

The Studio at Butler Library, as we imagine it, will host mix of scheduled events loosely related to digital humanities, along with providing an unstructured, community-driven workspace for all those interested in the applied aspects of book culture, data curation, knowledge design, big history, complex social systems, experimental philosophy and criticism, cultural analytics, network analysis, computational modeling, text mining, data visualization, and critical making

Developments in marine pCO2 measurement technology; towards sustained in situ observations

The oceanic uptake of anthropogenic CO2 causes pronounced changes to the marine carbonate system. High quality pCO2 measurements with good temporal and spatial coverage are required to monitor the oceanic uptake, identify regions with pronounced carbonate system changes, and observe the effectiveness of CO2 emission mitigation strategies. There are currently several instruments available, but many are unsuitable for autonomous deployments on in situ platforms such as gliders, moorings and Argo floats. We assess currently available technology on its suitability for in situ deployment, with a focus on optode technology developments. Optodes for pCO2 measurements provide a promising new technological approach, and were successfully calibrated over the range of 280–480 μatm applying modified time-domain dual lifetime referencing. A laboratory precision of 0.8 μatm (n = 10) and a response time (τ90) of 165 s were achieved, and with further development pCO2 optodes may become as widely used as their oxygen counterparts

A Look to Future Directions in Gene Therapy Research for Monogenic Diseases

The concept of gene therapy has long appealed to biomedical researchers and clinicians because it promised to treat certain diseases at their origins. In the last several years, there have been several trials in which patients have benefited from gene therapy protocols. This progress, however, has revealed important problems, including the problem of insertional oncogenesis. In this review, which focuses on monogenic diseases, we discuss the problem of insertional oncogenesis and identify areas for future research, such as developing more quantitative assays for risk and efficacy, and ways of minimizing the genotoxic effects of gene therapy protocols, which will be important if gene therapy is to fulfill its conceptual promise