Two-Face(s): ionized and neutral gas winds in the local Universe

We present a comprehensive study of the Na I $\lambda$5890, 5895 (Na I D) resonant lines in the Sloan Digital Sky Survey (SDSS, DR7) spectroscopic sample to look for neutral gas outflows in the local galaxies. Individual galaxy spectra are stacked in bins of M${\star}$ and SFR to investigate the dependence of galactic wind occurrence and velocity as a function of the galaxy position in the SFR-$M{\star}$ plane. In massive galaxies at the high SFR tail we find evidence of a significant blue-shifted Na I D absorption, which we interpret as evidence of neutral outflowing gas. The occurrence of the blue-shifted absorption is observed at the same significance for purely SF galaxies, AGN and composite systems at fixed SFR. In all classes of objects the blue-shift is the largest and the Na I D equivalent width the smallest for face-on galaxies while the absorption feature is at the systemic velocity for edge-on systems. This indicates that the neutral outflow is mostly perpendicular or biconical with respect to the galactic disk. We also compare the kinematics of the neutral gas with the ionized gas phase as traced by the [OIII]$\lambda$5007, H$\alpha$, [NII]$\lambda6548$ and [NII]$\lambda6584$ emission lines. Differently for the neutral gas phase, all the emission lines show evidence of perturbed kinematics only in galaxies with a significant level of nuclear activity and, they are independent from the disk inclination. In conclusion, we find that, in the local Universe, galactic winds show two faces which are related to two different ejection mechanisms, namely the neutral outflowing gas phase related to the SF activity along the galaxy disk and the ionized phase related to the AGN feedback. In both the neutral and ionized gas phases, the observed wind velocities suggest that the outflowing gas remains bound to the galaxy with no definitive effect on the gas reservoir.Comment: Accepted to A&A, 13 pages, 9 figure

On the robustness of the Hβ\beta Lick index as a cosmic clock in passive early-type galaxies

We examine the H$\beta$ Lick index in a sample of $\sim 24000$ massive ($\rm log(M/M_{\odot})>10.75$) and passive early-type galaxies extracted from SDSS at z<0.3, in order to assess the reliability of this index to constrain the epoch of formation and age evolution of these systems. We further investigate the possibility of exploiting this index as "cosmic chronometer", i.e. to derive the Hubble parameter from its differential evolution with redshift, hence constraining cosmological models independently of other probes. We find that the H$\beta$ strength increases with redshift as expected in passive evolution models, and shows at each redshift weaker values in more massive galaxies. However, a detailed comparison of the observed index with the predictions of stellar population synthesis models highlights a significant tension, with the observed index being systematically lower than expected. By analyzing the stacked spectra, we find a weak [NII]$\lambda6584$ emission line (not detectable in the single spectra) which anti-correlates with the mass, that can be interpreted as a hint of the presence of ionized gas. We estimated the correction of the H$\beta$ index by the residual emission component exploiting different approaches, but find it very uncertain and model-dependent. We conclude that, while the qualitative trends of the observed H$\beta$-z relations are consistent with the expected passive and downsizing scenario, the possible presence of ionized gas even in the most massive and passive galaxies prevents to use this index for a quantitative estimate of the age evolution and for cosmological applications.Comment: 20 pages, 11 figures, 1 table. Accepted for publication in MNRAS Main Journa

Identifying the lights position in photometric stereo under unknown lighting

Reconstructing the 3D shape of an object from a set of images is a classical problem in Computer Vision. Photometric stereo is one of the possible approaches. It stands on the assumption that the object is observed from a fixed point of view under different lighting conditions. The traditional approach requires that the position of the light sources is accurately known. It has been proved that the lights position can be estimated directly from the data, when at least 6 images of the observed object are available. In this paper, we give a Matlab implementation of the algorithm for solving the photometric stereo problem under unknown lighting, and propose a simple shooting technique to solve the bas-relief ambiguity.Comment: new versio

Experiments and modeling of the growth of C. sorokiniana in lab batch and BIOCOIL photobioreactors for lipid production

A novel mathematical model for the quantitative assessment of the effect of dissolved nitrogen on the autotrophic batch-growth and lipid accumulation of C. sorokiniana, is proposed in this work. Model results have been validated through comparison with suitable experimental data performed in lab photobioreactors. Further experiments have been then performed using a BIOCOIL operated in fed-batch mode. The experimental results have been successfully predicted through the proposed model. Therefore, the model might represent a first step toward the development of a tool for the scale-up and optimization of the operating conditions of BIOCOIL photobioreactors. Furthermore, the fatty acid methyl esters obtained by transesterification of lipids extracted from C. sorokiniana, have been analysed in view of the assessment of their usability for producing biofuels. Subsequently, on the basis of the fatty acids profile, a wide range of biodiesel fuel properties have been predicted through suitable software

Arsonists or firefighters? Affectiveness in agile software development

In this paper, we present an analysis of more than 500K comments from open-source repositories of software systems developed using agile methodologies. Our aim is to empirically determine how developers interact with each other under certain psychological conditions generated by politeness, sentiment and emotion expressed within developers' comments. Developers involved in an open-source projects do not usually know each other; they mainly communicate through mailing lists, chat, and tools such as issue tracking systems. The way in which they communicate a ects the development process and the productivity of the people involved in the project. We evaluated politeness, sentiment and emotions of comments posted by agile developers and studied the communication ow to understand how they interacted in the presence of impolite and negative comments (and vice versa). Our analysis shows that \ re ghters" prevail. When in presence of impolite or negative comments, the probability of the next comment being impolite or negative is 13% and 25%, respectively; ANGER however, has a probability of 40% of being followed by a further ANGER comment. The result could help managers take control the development phases of a system, since social aspects can seriously a ect a developer's productivity. In a distributed agile environment this may have a particular resonance

Can we avoid high coupling?

It is considered good software design practice to organize source code into modules and to favour within-module connections (cohesion) over between-module connections (coupling), leading to the oft-repeated maxim "low coupling/high cohesion". Prior research into network theory and its application to software systems has found evidence that many important properties in real software systems exhibit approximately scale-free structure, including coupling; researchers have claimed that such scale-free structures are ubiquitous. This implies that high coupling must be unavoidable, statistically speaking, apparently contradicting standard ideas about software structure. We present a model that leads to the simple predictions that approximately scale-free structures ought to arise both for between-module connectivity and overall connectivity, and not as the result of poor design or optimization shortcuts. These predictions are borne out by our large-scale empirical study. Hence we conclude that high coupling is not avoidable--and that this is in fact quite reasonable

Fractal Weyl law for Linux Kernel Architecture

We study the properties of spectrum and eigenstates of the Google matrix of a directed network formed by the procedure calls in the Linux Kernel. Our results obtained for various versions of the Linux Kernel show that the spectrum is characterized by the fractal Weyl law established recently for systems of quantum chaotic scattering and the Perron-Frobenius operators of dynamical maps. The fractal Weyl exponent is found to be $\nu \approx 0.63$ that corresponds to the fractal dimension of the network $d \approx 1.2$. The eigenmodes of the Google matrix of Linux Kernel are localized on certain principal nodes. We argue that the fractal Weyl law should be generic for directed networks with the fractal dimension $d<2$.Comment: RevTex 6 pages, 7 figs, linked to arXiv:1003.5455[cs.SE]. Research at http://www.quantware.ups-tlse.fr/, Improved version, changed forma

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.

Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity, we performed genome-wide analyses of circulating HDL cholesterol, LDL cholesterol, and triglyceride levels in up to 120,979 individuals of European, African, Asian, Hispanic, and Brazilian ancestry, with follow-up of suggestive associations in an additional 131,012 individuals. We find four loci, in/near CLASP1, LHX1, SNTA1, and CNTNAP2, that are associated with circulating lipid levels through interaction with physical activity; higher levels of physical activity enhance the HDL cholesterol-increasing effects of the CLASP1, LHX1, and SNTA1 loci and attenuate the LDL cholesterol-increasing effect of the CNTNAP2 locus. The CLASP1, LHX1, and SNTA1 regions harbor genes linked to muscle function and lipid metabolism. Our results elucidate the role of physical activity interactions in the genetic contribution to blood lipid levels

Genome-wide association analysis on normal hearing function identifies PCDH20 and SLC28A3 as candidates for hearing function and loss

Hearing loss and individual differences in normal hearing both have a substantial genetic basis. Although many new genes contributing to deafness have been identified, very little is known about genes/variants modulating the normal range of hearing ability. To fill this gap, we performed a two-stage meta-analysis on hearing thresholds (tested at 0.25, 0.5, 1, 2, 4, 8 kHz) and on pure-tone averages (low-, medium- and high-frequency thresholds grouped) in several isolated populations from Italy and Central Asia (total N = 2636). Here, we detected two genome-wide significant loci close to PCDH20 and SLC28A3 (top hits: rs78043697, P = 4.71E-10 and rs7032430, P = 2.39E-09, respectively). For both loci, we sought replication in two independent cohorts: B58C from the UK (N = 5892) and FITSA from Finland (N = 270). Both loci were successfully replicated at a nominal level of significance (P < 0.05). In order to confirm our quantitative findings, we carried out RT-PCR and reported RNA-Seq data, which showed that both genes are expressed in mouse inner ear, especially in hair cells, further suggesting them as good candidates for modulatory genes in the auditory system. Sequencing data revealed no functional variants in the coding region of PCDH20 or SLC28A3, suggesting that variation in regulatory sequences may affect expression. Overall, these results contribute to a better understanding of the complex mechanisms underlying human hearing function

Application of a New Method for GWAS in a Related Case/Control Sample with Known Pedigree Structure: Identification of New Loci for Nephrolithiasis

In contrast to large GWA studies based on thousands of individuals and large meta-analyses combining GWAS results, we analyzed a small case/control sample for uric acid nephrolithiasis. Our cohort of closely related individuals is derived from a small, genetically isolated village in Sardinia, with well-characterized genealogical data linking the extant population up to the 16th century. It is expected that the number of risk alleles involved in complex disorders is smaller in isolated founder populations than in more diverse populations, and the power to detect association with complex traits may be increased when related, homogeneous affected individuals are selected, as they are more likely to be enriched with and share specific risk variants than are unrelated, affected individuals from the general population. When related individuals are included in an association study, correlations among relatives must be accurately taken into account to ensure validity of the results. A recently proposed association method uses an empirical genotypic covariance matrix estimated from genome-screen data to allow for additional population structure and cryptic relatedness that may not be captured by the genealogical data. We apply the method to our data, and we also investigate the properties of the method, as well as other association methods, in our highly inbred population, as previous applications were to outbred samples. The more promising regions identified in our initial study in the genetic isolate were then further investigated in an independent sample collected from the Italian population. Among the loci that showed association in this study, we observed evidence of a possible involvement of the region encompassing the gene LRRC16A, already associated to serum uric acid levels in a large meta-analysis of 14 GWAS, suggesting that this locus might lead a pathway for uric acid metabolism that may be involved in gout as well as in nephrolithiasis