237 research outputs found
The Engineering Hubs and Spokes Project - institutional cooperation in educational design and delivery
The emergence of blended learning techniques that embrace a combination of face-to-face and
online learning environments offers a raft of opportunity for flexibility in education. While much
writing has focused on the opportunities for flexibility for the students and teachers, this paper
focuses on the opportunities for effective sharing of expertise and effort between institutions.
The Engineering 'Hubs and Spokes' project is a collaboration between The Australian National
University and the University of South Australia. It draws on the strengths of each to improve the
range and quality of educational opportunities for students. Two components of the project are
underpinned by blended teaching and learning techniques: sharing of courses at the advanced
undergraduate level; and development of an integrated graduate development program.
We describe choices made, benefits identified, and the challenges encountered in the early stages
of the project. We discuss recommendations for the future of cooperation in educational design
and delivery, and comment on the opportunities that arise for structural reform of the higher
education sector
The Influence of Strain Rate on the Mode III Interlaminar Fracture of Composite Materials
The Mode III interlaminar fracture toughness, GIIIc, of composite materials based on both thermoplastic and thermosetting-matrices have been investigated using the edge crack torsion (ECT) test geometry. Tests were undertaken at room temperature and ove
Multi-signal quality monitoring of aluminium resistance spot welding using principal component analysis
The current migration to lighter materials in car bodies, such as aluminium, has resulted in significant challenges for joining in production. Resistance Spot Welding (RSW) is the primary sheet metal joining technique in the automotive industry due to its quick cycle time, low cost and high strength. However, aluminium RSW suffers from problems with quality consistency compared to steel, requiring more frequent interventions. This results in a higher cost in production through increased cycle times and the use of consumable electrodes.
To address this issue, a new multi-signal quality monitoring technique is proposed to allow for complete real-time quality monitoring of aluminium spot welds in production. The proposed solution utilises multiple signals during welding and an efficient algorithm using Principal Component Analysis to determine the signal shapes of interest. It was found that an RMSE of 119N could be achieved when predicting the strength of aluminium spot welds using multiple signals, which is approximately ±5% of the mean strength of the welds and an improvement on previous attempts.This research was supported by an Australian Government Research Training Program (RTP) Scholarship
The influence of consolidation force on the performance of AFP manufactured laminates
With the increasing use of carbon/glass fibre reinforced polymer composites for large components like wing skins, fuselages and fuel tanks in aircrafts and next generation of spacecraft, utilization of advanced automated manufacturing is critical for mass production. In-situ consolidation in automated fibre placement (AFP) technology through merging several manufacturing stages like cutting, curing and consolidation has opened up a wider range of applications as well as new markets for composite materials in several sectors including aerospace and automobile in large scale. Nevertheless, the quality and integrity of AFP manufactured composites is heavily dependent on large number of variables and parameters like lay-up speed, curing/melting temperature and consolidation force. In order to establish and understand a correlation between the key parameters in AFP and the mechanical properties, several parametric experiments were performed. This is done through manufacturing uni-directional carbon fibre reinforced polymer laminates and identifying some of their main mechanical properties at different location along the length of samples. It was found that, the strength of laminates at different locations is critically dependent on the effect of those parameters
Sustainable aluminium recycling of end-of-life products: A joining techniques perspective
The sustainable management of aluminium has become crucial due to the exponential growth in global demand. The transition to a sustainable society with lightweight electric vehicles has led to the increasing use of aluminium in the transportation sector. This has consequently led to the importance of aluminium recycling to prevent the valuable material stream going to landfill. In addition, the extraction of primary aluminium has high environmental impact due to the high energy consumption and waste generation in comparison to secondary aluminium processing. Despite being one of the most recycled metals, ongoing trends of multi-material designs and the associated joining choices have caused increasing difficulty of separating aluminium with high purity.
This paper evaluates the types of joining techniques causing impurities in the aluminium streams, and the relationship between particle size reduction and the presence of impurities due to joints particularly for end-of-life vehicles. An empirical experiment in a leading European recycling facility was conducted and demonstrated that mechanical fasteners, such as machine screws, socket screws, bolt screws and rivets, are the major types of joining technique causing impurities. Based on the observations from this case study, the characteristics of imperfectly liberated joints are examined. A Life Cycle Assessment (LCA) is also performed to evaluate the environmental impact of recycling different aluminium scrap qualities with varying impurity levels. The outcomes are then used to provide ecodesign guidelines aimed at improving the quality and increase the quantity of recycled aluminium.This study is supported by the Commonwealth Government CRC Program (AutoCRC), the Australian National University, and the Centre for Industrial Management, University of Leuven
Functional electrical stimulation for foot drop in multiple sclerosis: a systematic review and meta-analysis of the effect on gait speed
Objective:
To review the efficacy of functional electrical stimulation (FES) used for foot drop in people with multiple sclerosis (pwMS) on gait speed in short and long walking performance tests.
Data sources:
Five databases (Cochrane Library, CINAHL, Embase, MEDLINE, Pubmed) and reference lists were searched.
Study selection:
Studies of both observational and experimental design where gait speed data in pwMS could be extracted were included.
Data extraction:
Data were independently extracted and recorded. Methodological quality was assessed using the Effective Public Health Practice Project (EPHPP) tool.
Data synthesis:
Nineteen studies (described in 20 articles) recruiting 490 pwMS were identified and rated moderate or weak, with none gaining a strong rating. All studies rated weak for blinding. Initial and ongoing orthotic and therapeutic effects were assessed with regards to the impact of FES on gait speed in short and long walking tests. Meta-analyses of the short walk tests revealed a significant initial orthotic effect (t = 2.14, p = 0.016) with a mean increase in gait speed of 0.05 meters per second (m/s) and ongoing orthotic effect (t = 2.81, p = 0.003) with a mean increase of 0.08m/s. There were no initial or ongoing effect on gait speed in long walk tests and no therapeutic effect on gait speed in either short or long walk tests.
Conclusions:
FES used for foot drop has a positive initial and ongoing effect on gait speed in short walking tests. Further fully-powered randomized controlled trials comparing FES with alternative treatments are required
Intensive Mode Teaching of a Humanitarian Engineering Course to Enhance Service-Learning
Service-learning is a common component of many humanitarian engineering education programs. Students engage with external organisations and communities, often spending time intensively, on projects linked to their studies. To help prepare students for substantial service-learning initiatives a dedicated humanitarian engineering course was developed. To better represent service-learning and enable a greater variety of teaching and learning activities, the course was delivered over five weeks using intensive mode teaching. This enabled a portion of the class to be involved with a two-week scaffolded immersive international experience running in parallel to the campus delivery. Threshold concept and capability theory was used to evaluate the course and identify what elements of the course supported or hindered development of student thresholds. Results identified the main student threshold to be the ability to take account of social factors in engineering design and the activities enabled by the intensive mode teaching were among the strongest contributions to the achievement of this threshold, in particular elements of the international experience. This highlights the opportunities for intensive mode teaching in supporting activities related to service-learnin
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Transcript specific regulation of expression influences susceptibility to multiple sclerosis.
Genome-wide association studies (GWAS) have identified over 100 loci containing single nucleotide variants (SNVs) that influence the risk of developing multiple sclerosis (MS). Most of these loci lie in non-coding regulatory regions of the genome that are active in immune cells and are therefore thought to modify risk by altering the expression of key immune genes. To explore this hypothesis we screened genes flanking MS-associated variants for evidence of allele specific expression (ASE) by quantifying the transcription of coding variants in linkage disequilibrium with MS-associated SNVs. In total, we were able to identify and successfully analyse 200 such coding variants (from 112 genes) in both CD4+ and CD8+ T cells from 106 MS patients and 105 controls. Fifty-six of these coding variants (from 43 genes) showed statistically significant evidence of ASE in one or both cell types. In the Lck interacting transmembrane adaptor 1 gene (LIME1), for example, we were able to show that in both cell types, the MS-associated variant rs2256814 increased the expression of some transcripts while simultaneously reducing the expression of other transcripts. In CD4+ cells from an additional independent set of 96 cases and 93 controls we were able to replicate the effect of this SNV on the balance of alternate LIME1 transcripts using qPCR (p = 5 × 10-24). Our data thus indicate that some of the MS-associated SNVs identified by GWAS likely exert their effects on risk by distorting the balance of alternate transcripts rather than by changing the overall level of gene expression
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