Analise semiotica de um ava (ambiente virtual de ensino aprendizagem) : características cts através da escada semotica de Stamper

Este artigo demonstra um estudo e aplicação da análise semiótica, para a avaliação de interfaces de ambientes virtuais de ensino-aprendizagem (AVA), de acordo com a escada semiótica de Stamper. Com base nas características CTS (Ciência,Tecnologia e Sociedade) encontrada nas camadas “degrais” da escada. Em específico, usamos a metodologia para qualidade de interfaces definida por Schimiguel, que instancia critérios de qualidade para cada uma das camadas da escada semiótica de Stamper. Com base nos resultados dessa investigação foi possível sugerir algumas recomendações nas seis camadas analisadas, sinalizando ainda para cada uma dessas recomendações um enfoque CTS, uma descrição que tem como propósito facilitar a implementação e otimização de AVAS

Electrospray Mass Spectrometric Detection of Products and Short-Lived Intermediates in Aqueous Aerosol Microdroplets Exposed to a Reactive Gas

The intermediates ISO_3^- (m/z = 207) and IS2O3- (m/z = 239) generated in aqueous (NaI/Na_2S2O_3) microdroplets traversing dilute O_3 gas plumes are detected via online electrospray mass spectrometry within ∼1 ms, and their stabilities gauged by collisionally induced dissociation. The simultaneous detection of anionic reactants and the S_2O_6^(2-), HSO_4^-, IO_3^-, and I_3^- products as a function of experimental conditions provides evidence of genuinely interfacial reaction kinetics. Although O_3(aq) reacts about 3 times faster with I- than with S_2O_3^(2-) in bulk solution, only S_2O_3^(2-) is significantly depleted in the interfacial layers of [I^-]/[S_2O_3^(2-)] = 10 microdroplets below [O_3(g)] ∼ 50 ppm

Orange essential oil inclusion compleX with B-cyclodextrin.

Cyclodextrins due to its structure composed of internal cavities hydrophobic and essentially hydrophilic extremities has the ability to form inclusion complexes with various substances. Thus, the objective of this study was to produce an inclusion complex of ?-CD with Valência orange essential oil (OEO), using the precipitation method and characterizing it through the scanning electron microscopy analysis (SEM) and differential scanning calorimetry (DSC), and to characterize the orange essential oil by gas chromatography-mass spectrometry (CG-EM) The d-limonene (95.56%) was the major component, followed by ?-Myrcene (2.35%), octanal (0.55%), ?-pinene (0.54%), ?-linalol (0.45%), cyclohexene (0.29%) and finally, decanal (0.26%)of OEO. The results show that waspossible to produce aninclusion omplexbetween orange essential oil and ?-CD. The inclusion complex showed greater interaction with the orange essential oil when compared to the physical mixture

Produção de suínos em sistema de ciclo completo: custos e receitas da utilização dos dejetos.

Este trabalho teve como objetivo estimar os custos de distribuição dos dejetos de uma criação de suínos com 42 matrizes em sistema de ciclo completo e as receitas obtidas do seu uso como substituto dos fertilizante químicos. Foram definidas as quantidades de dejetos produzidas, a área de aplicação e os custos de transporte. Posteriormente estimadas as receitas que os dejetos gerariam substituindo fertilizantes químicos como a uréia, o super triplo e o cloreto de potássio.bitstream/item/111047/1/Cot474.pd

Fowl typhoid in Argentine Republic

Luego de un brote de Tifosis en un criadero con 100.000 aves en producción a jaula (50% Leghorn y 50% AA-Harco), un 8,38% de positivos (Harco) a la prueba de aglutinación rápida, son trasladados a tinglado individual y alojados igualmente en jaula. Luego de 50 coprocultivos negativos, los animales son reanalizados con la misma prueba 30~60-90 y 120 días después, comprobándose que dichos positivos disminuían del 100 al 32%, no habiéndose constatado en todo ese tiempo, diferencia con su lote similar. Transcurrido ese período, 30 animales son descargados con cepa virulenta, comprobándose que sólo el 1% muere por Tifosis, frente al lote testigo donde los insucesos son del 50% Estos hechos son analizados estadísticamente entendiendo que la prueba de aglutinación no debe aplicarse con el mismo criterio que para la pullorosis ya que, según los resultados, muestra un valor muy relativo. Se efectúan paralelamente, consideraciones inmunológicas sobre la posible importancia de la lg A en los mecanismos de defensa de las aves.After a Typhoid outbreak in a farm with 100.000 birds in production in cages (50% Leghorn and 50% AA-Harco), 8,38% of positive reactors to the quick agglutination test (Harco) were transferred to an individual house also in cages. After 50 negative coprocultures, the birds are again assayed by the same test 30-60-90 and 120 days after, finding that said positives decreased from 100 to 32%. No difference was noted during that period with the similar lot. After that time, 30 birds are challenged with a virulent strain and only 1% die of Typhoid; as compared with the control group where mortality was 50%. These facts are statistically analyzed finding that the agglutination test should not be used with the same criteria as for pullorum, since, according to the findings, its value is quite relative. At the same time, immunological considerations were effected on the possible importance of Ig G and Ig A in the defense mechanisms of birds against infections caused by enterobacteria.Facultad de Ciencias Veterinaria

Sustained virologic response to direct-acting antiviral agents predicts better outcomes in hepatitis C virus-infected patients: A retrospective study

Direct-acting antiviral agents (DAAs) are extremely effective in eradicating hepatitis C virus (HCV) in chronically infected patients. However, the protective role of the sustained virologic response (SVR) achieved by second- and third-generation DAAs against the onset of hepatocellular carcinoma (HCC) and mortality is less well established

Collapse and revival of the monopole mode of a degenerate Bose gas in an isotropic harmonic trap

We study the monopole (breathing) mode of a finite temperature Bose-Einstein condensate in an isotropic harmonic trap recently developed by Lobser et al. [Nat. Phys. 11, 1009 (2015)]. We observe a nonexponential collapse of the amplitude of the condensate oscillation followed by a partial revival. This behavior is identified as being due to beating between two eigenmodes of the system, corresponding to in-phase and out-of-phase oscillations of the condensed and noncondensed fractions of the gas. We perform finite temperature simulations of the system dynamics using the Zaremba-Nikuni-Griffin methodology [J. Low Temp. Phys. 116, 277 (1999)], and find good agreement with the data, thus confirming the two mode description

Potential for Lung Recruitment and Ventilation-Perfusion Mismatch in Patients With the Acute Respiratory Distress Syndrome From Coronavirus Disease 2019

OBJECTIVES: Severe cases of coronavirus disease 2019 develop the acute respiratory distress syndrome, requiring admission to the ICU. This study aimed to describe specific pathophysiological characteristics of acute respiratory distress syndrome from coronavirus disease 2019. DESIGN: Prospective crossover physiologic study. SETTING: ICU of a university-affiliated hospital from northern Italy dedicated to care of patients with confirmed diagnosis of coronavirus disease 2019. PATIENTS: Ten intubated patients with acute respiratory distress syndrome and confirmed diagnosis of coronavirus disease 2019. INTERVENTIONS: We performed a two-step positive end-expiratory pressure trial with change of 10\u2009cm H2O in random order. MEASUREMENTS AND MAIN RESULTS: At each positive end-expiratory pressure level, we assessed arterial blood gases, respiratory mechanics, ventilation inhomogeneity, and potential for lung recruitment by electrical impedance tomography. Potential for lung recruitment was assessed by the recently described recruitment to inflation ratio. In a subgroup of seven paralyzed patients, we also measured ventilation-perfusion mismatch at lower positive end-expiratory pressure by electrical impedance tomography. At higher positive end-expiratory pressure, respiratory mechanics did not change significantly: compliance remained relatively high with low driving pressure. Oxygenation and ventilation inhomogeneity improved but arterial CO2 increased despite unchanged respiratory rate and tidal volume. The recruitment to inflation ratio presented median value higher than previously reported in acute respiratory distress syndrome patients but with large variability (median, 0.79 [0.53-1.08]; range, 0.16-1.40). The FIO2 needed to obtain viable oxygenation at lower positive end-expiratory pressure was significantly correlated with the recruitment to inflation ratio (r = 0.603; p = 0.05). The ventilation-perfusion mismatch was elevated (median, 34% [32-45%] of lung units) and, in six out of seven patients, ventilated nonperfused units represented a much larger proportion than perfused nonventilated ones. CONCLUSIONS: In patients with acute respiratory distress syndrome from coronavirus disease 2019, potential for lung recruitment presents large variability, while elevated dead space fraction may be a specific pathophysiological trait. These findings may guide selection of personalized mechanical ventilation settings

Pre-Procedural Statin Use Is Associated with Improved Long-Term Survival and Reduced Major Cardiovascular Events in Patients Undergoing Carotid Artery Stenting: A Retrospective Study

Carotid artery stenting (CAS) is a minimal invasive procedure used to resolve carotid occlusion that can be affected by peri-procedural complications. Statin use before CAS has shown to reduce peri-procedural risk and improve survival, though time-dependent cofactors that influence mortality has not been considered. The aim of this study was to evaluate long-term survival of patients who undergo CAS considering new occurred major adverse cardiovascular event (MACE) as time-dependent cofactor. In this study, 171 high cardiovascular risk patients (age 72 \ub1 8 years, 125 males) were enrolled after CAS procedure and were followed for a median of 8.4 years. Death occurred in 44% of patients with a mean time to death of 69 \ub1 39 months and MACE in 34% with a mean time of 35 \ub1 42 months. In patients who used or not statins at baseline, death occurred in 33% and 65%, respectively (p < 0.001). Survival analysis showed that statin use reduced risk of death (hazard ratio HR 0.36, 95% confidence interval CI 0.23\u207b0.58, p < 0.0001). Including MACE as time-dependent variable did not change beneficial effects of statins. Additionally, statin use was associated with a protective effect on MACE (HR 0.48, 95% CI 0.27\u207b0.85, p = 0.012); particularly, the prevalence of stroke was reduced by 59% (p = 0.018). In multivariate analysis, effects of statins were independent of demographic and anthropometric variables, prevalence of cardiovascular risk factors, renal function, antiplatelet use, and MACE occurrence. In conclusion, use of statins before CAS procedure is associated with increased long-term survival and reduced MACE occurrence. This evidence supports the hypothesis that statin use before CAS might be beneficial in high risk patients