Background independence in a nutshell

We study how physical information can be extracted from a background independent quantum system. We use an extremely simple `minimalist' system that models a finite region of 3d euclidean quantum spacetime with a single equilateral tetrahedron. We show that the physical information can be expressed as a boundary amplitude. We illustrate how the notions of "evolution" in a boundary proper-time and "vacuum" can be extracted from the background independent dynamics.Comment: 19 pages, 19 figure

Least squares optimization: From theory to practice

Nowadays, Nonlinear Least-Squares embodies the foundation of many Robotics and Computer Vision systems. The research community deeply investigated this topic in the last few years, and this resulted in the development of several open-source solvers to approach constantly increasing classes of problems. In this work, we propose a unified methodology to design and develop efficient Least-Squares Optimization algorithms, focusing on the structures and patterns of each specific domain. Furthermore, we present a novel open-source optimization system that addresses problems transparently with a different structure and designed to be easy to extend. The system is written in modern C++ and runs efficiently on embedded systemsWe validated our approach by conducting comparative experiments on several problems using standard datasets. The results show that our system achieves state-of-the-art performances in all tested scenarios

Three dimensional loop quantum gravity: coupling to point particles

We consider the coupling between three dimensional gravity with zero cosmological constant and massive spinning point particles. First, we study the classical canonical analysis of the coupled system. Then, we go to the Hamiltonian quantization generalizing loop quantum gravity techniques. We give a complete description of the kinematical Hilbert space of the coupled system. Finally, we define the physical Hilbert space of the system of self-gravitating massive spinning point particles using Rovelli's generalized projection operator which can be represented as a sum over spin foam amplitudes. In addition we provide an explicit expression of the (physical) distance operator between two particles which is defined as a Dirac observable.Comment: Typos corrected and references adde

Graviton propagator in loop quantum gravity

We compute some components of the graviton propagator in loop quantum gravity, using the spinfoam formalism, up to some second order terms in the expansion parameter.Comment: 41 pages, 6 figure

Simple model for quantum general relativity from loop quantum gravity

New progress in loop gravity has lead to a simple model of `general-covariant quantum field theory'. I sum up the definition of the model in self-contained form, in terms accessible to those outside the subfield. I emphasize its formulation as a generalized topological quantum field theory with an infinite number of degrees of freedom, and its relation to lattice theory. I list the indications supporting the conjecture that the model is related to general relativity and UV finite.Comment: 8 pages, 3 figure

Euclidean three-point function in loop and perturbative gravity

We compute the leading order of the three-point function in loop quantum gravity, using the vertex expansion of the Euclidean version of the new spin foam dynamics, in the region of gamma<1. We find results consistent with Regge calculus in the limit gamma->0 and j->infinity. We also compute the tree-level three-point function of perturbative quantum general relativity in position space, and discuss the possibility of directly comparing the two results.Comment: 16 page

A new look at loop quantum gravity

I describe a possible perspective on the current state of loop quantum gravity, at the light of the developments of the last years. I point out that a theory is now available, having a well-defined background-independent kinematics and a dynamics allowing transition amplitudes to be computed explicitly in different regimes. I underline the fact that the dynamics can be given in terms of a simple vertex function, largely determined by locality, diffeomorphism invariance and local Lorentz invariance. I emphasize the importance of approximations. I list open problems.Comment: 15 pages, 5 figure

The Full Monty? Meaning construction and performative possibilities in media depictions of the male strip show

This article questions the progressive potential of media depictions of male strip shows. I examine two overriding discourses within media representations, comparing these to the experiences of male dancers and female customers gleaned through ethnographic fieldwork in two strip venues. Namely, the media’s portrayal of the masculinity of male strippers as ‘fragile’; together with the construction of dancers as ‘fantasy’ subjects who know ‘what women want’. The article interrogates these constructions in relation to a critique of women’s opportunities to exercise an erotic ‘gaze’; the operation of racist and classist discourses of consuming ‘difference’ and Othering customers; and male dancers’ attempts to construct a viable sense of workplace self in the light of negative constructions of sexual labour

Close Encounters: Intimate service interactions in lap dancing work as a nexus of ‘self-others-things’

Drawing on ethnographic research on lap dancing work, this paper focuses on how the subjectivities, interactions and settings that constitute the lap dancing industry come into being through three interrelated processes of encoding, embodying and embedding. In considering how these processes combine to ‘enact’ the industry, the paper draws on Merleau Ponty’s understanding of the world as a dynamic nexus of ‘self-others-things’. Focusing on how this nexus shapes lived experiences of intimate service interactions, the analysis considers how dancers continually negotiate customers’ expectations of the service encounter given the ways in which these are: (i) encoded in depictions of lap dancing work in marketing and advertising materials on club websites; (ii) embodied by lap dancers through their interactions with customers; and (iii) embedded within the materiality of lap dancing clubs. The paper shows how intimate service encounters can be understood as the outcome of a nexus of ‘self-others-things’ through which particular organizational subjectivities and settings are brought into being through these three interrelated processes

Soluble FLT1 Gene Therapy Alleviates Brain Arteriovenous Malformation Severity

Background and purposeBrain arteriovenous malformation (bAVM) is an important risk factor for intracranial hemorrhage. Current therapies are associated with high morbidities. Excessive vascular endothelial growth factor has been implicated in bAVM pathophysiology. Because soluble FLT1 binds to vascular endothelial growth factor with high affinity, we tested intravenous delivery of an adeno-associated viral vector serotype-9 expressing soluble FLT1 (AAV9-sFLT1) to alleviate the bAVM phenotype.MethodsTwo mouse models were used. In model 1, bAVM was induced in R26CreER;Eng2f/2f mice through global Eng gene deletion and brain focal angiogenic stimulation; AAV2-sFLT02 (an AAV expressing a shorter form of sFLT1) was injected into the brain at the time of model induction, and AAV9-sFLT1, intravenously injected 8 weeks after. In model 2, SM22αCre;Eng2f/2f mice had a 90% occurrence of spontaneous bAVM at 5 weeks of age and 50% mortality at 6 weeks; AAV9-sFLT1 was intravenously delivered into 4- to 5-week-old mice. Tissue samples were collected 4 weeks after AAV9-sFLT1 delivery.ResultsAAV2-sFLT02 inhibited bAVM formation, and AAV9-sFLT1 reduced abnormal vessels in model 1 (GFP versus sFLT1: 3.66±1.58/200 vessels versus 1.98±1.29, P&lt;0.05). AAV9-sFLT1 reduced the occurrence of bAVM (GFP versus sFLT1: 100% versus 36%) and mortality (GFP versus sFLT1: 57% [12/22 mice] versus 24% [4/19 mice], P&lt;0.05) in model 2. Kidney and liver function did not change significantly. Minor liver inflammation was found in 56% of AAV9-sFLT1-treated model 1 mice.ConclusionsBy applying a regulated mechanism to restrict sFLT1 expression to bAVM, AAV9-sFLT1 can potentially be developed into a safer therapy to reduce the bAVM severity