5,841 research outputs found

    The London Ambassadorship of David K.E. Bruce during the Wilson-Johnson years, 1964-68

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    Using recently released sources, this article offers a fresh perspective on the London ambassadorship of David K. E. Bruce in the years of Harold Wilson and Lyndon Johnson, 1964–68. Bruce's running of the US Embassy is examined, as are his views of the Anglo-American relationship. Further attention is given to his diplomatic management of the Anglo-American relationship in the context of the difficult personal relations between Wilson and Johnson and with regard to policy differences over the Vietnam War and Britain's position as a world power. It is argued that while Bruce did help to ease some of the personal strains between Wilson and Johnson, he was generally less significant to the White House than has previously been asserted. It is also contended that his vision of Britain joining the EEC, yet retaining extensive military commitments beyond Europe was not viable

    Communication: 'What now for Britain?' The state department's intelligence assessment of the 'Special Relationship' 7 February 1968

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    The period 1967-1968 was a difficult one for the Anglo-American relationship, as a result of developments such as British defense cuts “East of Suez.” In the run-up to a visit to Washington by Prime Minister Harold Wilson in February 1968, the State Department's Intelligence and Research Bureau provided a lively and detailed evaluation of American bonds with Britain. The analysis maintained that the relationship was based on deeply established cooperation in defense, diplomacy and intelligence, and that despite recent problems Britain would remain of unparalleled importance as an American ally. The immediate impact of the memorandum in the White House of Lyndon B. Johnson was quite limited, but among other things the document helps to explain the ready blossoming of close high-level Anglo-American bonds during, for example, the Falklands War of 1982. The most important sections of the memorandum are reproduced, and a brief analysis is provided to put the issues in context

    Sequence variation in the haemagglutinin-neuraminidase gene of human parainfluenza virus type 3 isolates in the UK

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    The sequence variation in a 934 base-pair region of the gene encoding the haemagglutinin-neuraminidase of five human parainfluenza virus type 3 (HPIV3) isolates was determined together with that of a prototype UK strain. All of the clinical isolates were from the Manchester area of the UK and were obtained in 1990. 1991 and 1993. The gene segment was amplified by the polymerase chain reaction using HPIVB-specific oligonucleotide primers. The nucleotide homology of the strains was high, around 99% and specific differences in the UK sequences when compared with that of the US prototype strain were identified. In addition, a number of isolate-specific differences were seen. No correlation was detected between the observed nucleotide mutations and the year of isolation, which supports the hypothesis that HPIV3 shows cocirculation of a heterogeneous population of viruses rather than varying with time in a linear fashion. However, the data suggested that geographically-defined genetic lineages of HPIV3 may exist

    Concentrations and snow-atmosphere fluxes of reactive nitrogen at Summit, Greenland

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    Concentrations and fluxes of NOy (total reactive nitrogen), ozone concentrations and fluxes of sensible heat, water vapor, and momentum were measured from May 1 to July 20, 1995 at Summit, Greenland. Median NOy concentrations declined from 947 ppt in May to 444 ppt by July. NOy fluxes were observed into and out of the snow, but the magnitudes were usually below 1 μmol m−2 h−1 because of the low HNO3 concentration and weak turbulence over the snow surface. Some of the highest observed fluxes may be due to temporary storage by equilibrium sorption of peroxyacetylnitrate (PAN) or other organic nitrogen species on ice surfaces in the upper snowpack. Sublimation of snow at the surface or during blowing snow events is associated with efflux of NOy from the snowpack. Because the NOy fluxes during summer at Summit are bidirectional and small in magnitude, the net result of turbulent NOyexchange is insignificant compared to the 2 μmol m−2 d−1 mean input from fresh snow during the summer months. If the arctic NOy reservoir is predominantly PAN (or compounds with similar properties), thermal dissociation of this NOy is sufficient to support the observed flux of nitrate in fresh snow. Very low HNO3 concentrations in the surface layer (1% of total NOy) reflect the poor ventilation of the surface layer over the snowpack combined with the relatively rapid uptake of HNO3 by fog, falling snow, and direct deposition to the snowpack

    Evaluation of the Environmental Impact of Milk Quotas

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    The aim of this study is to examine the environmental impacts of the different systems for allocation and transfer of milk quota under the Common Agricultural Policy (CAP) in individual Member States of the European Union (EU). In particular, it seeks to identify the ways in which differences in the implementation of milk quota regimes can impact on various sectoral and farm management trends and the environmental implications of these

    Defining thalamic nuclei and topographic connectivity gradients in vivo.

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    The thalamus consists of multiple nuclei that have been previously defined by their chemoarchitectual and cytoarchitectual properties ex vivo. These form discrete, functionally specialized, territories with topographically arranged graduated patterns of connectivity. However, previous in vivo thalamic parcellation with MRI has been hindered by substantial inter-individual variability or discrepancies between MRI derived segmentations and histological sections. Here, we use the Euclidean distance to characterize probabilistic tractography distributions derived from diffusion MRI. We generate 12 feature maps by performing voxel-wise parameterization of the distance histograms (6 feature maps) and the distribution of three-dimensional distance transition gradients generated by applying a Sobel kernel to the distance metrics. We use these 12 feature maps to delineate individual thalamic nuclei, then extract the tractography profiles for each and calculate the voxel-wise tractography gradients. Within each thalamic nucleus, the tractography gradients were topographically arranged as distinct non-overlapping cortical networks with transitory overlapping mid-zones. This work significantly advances quantitative segmentation of the thalamus in vivo using 3T MRI. At an individual subject level, the thalamic segmentations consistently achieve a close relationship with a priori histological atlas information, and resolve in vivo topographic gradients within each thalamic nucleus for the first time. Additionally, these techniques allow individual thalamic nuclei to be closely aligned across large populations and generate measures of inter-individual variability that can be used to study both basic function and pathological processes in vivo
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