Effect of immobilization on the EEG of the baboon. Comparison with telemetry results from unrestricted animals

The EEG of the baboon was studied under two very different sets of conditions: 37 were totally immobolized while 12 were studied in their free movements with 4 channel telemetry. For the immobilzed, 3 stages were described: (1) activation, record desynchronized; (2) rest with 13-15 cm/sec rhythm, like the human alpha rhythm stage but with eyes open or closed; (3)relaxation with a decrease in 13-15 rhythm and the appearance of 5-7 cm/sec theta waves, eyelids closed, animal apparently sleeping. For the free animals the rest stage appeared when the animal's attention was not directed anywhere and there was no relaxation stage. It is concluded that the EEG pattern of the immobilized animal that was described as the "relaxation" stage really represents a special functional state which one must distinguish clearly from the physiological stages of sleep

MRI/TRUS data fusion for brachytherapy

BACKGROUND: Prostate brachytherapy consists in placing radioactive seeds for tumour destruction under transrectal ultrasound imaging (TRUS) control. It requires prostate delineation from the images for dose planning. Because ultrasound imaging is patient- and operator-dependent, we have proposed to fuse MRI data to TRUS data to make image processing more reliable. The technical accuracy of this approach has already been evaluated. METHODS: We present work in progress concerning the evaluation of the approach from the dosimetry viewpoint. The objective is to determine what impact this system may have on the treatment of the patient. Dose planning is performed from initial TRUS prostate contours and evaluated on contours modified by data fusion. RESULTS: For the eight patients included, we demonstrate that TRUS prostate volume is most often underestimated and that dose is overestimated in a correlated way. However, dose constraints are still verified for those eight patients. CONCLUSIONS: This confirms our initial hypothesis

High resolution magnetic microscopy based on semi-encapsulated graphene Hall sensors

The realization of quantitative, noninvasive sensors for ambient magnetic imaging with high spatial and magnetic field resolution remains a major challenge. To address this, we have developed a relatively simple process to fabricate semi-encapsulated graphene/hBN Hall sensors assembled by dry transfer onto pre-patterned gold contacts. 1 lm-sized Hall cross sensors at a drive current of 0.5 lA exhibit excellent room temperature sensitivity, SI 700 V/AT, and good minimum detectable fields, Bmin ¼ 0.54 G/Hz0.5 at a measurement frequency of 1 kHz, with considerable scope for further optimization of these parameters. We illustrate their application in an imaging study of labyrinth magnetic domains in a ferrimagnetic yttrium iron garnet film

Imaging of strong nanoscale vortex pinning in GdBaCuO high-temperature superconducting tapes

The high critical current density of second-generation high-temperature superconducting (2G-HTS) tapes is the result of the systematic optimisation of the pinning landscape for superconducting vortices through careful engineering of the size and density of defects and non-superconducting second phases. Here, we use scanning Hall probe microscopy to conduct a vortex-resolved study of commercial GdBaCuO tapes in low fields for the first time and complement this work with “local” magnetisation and transport measurements. Magnetic imaging reveals highly disordered vortex patterns reflecting the presence of strong pinning from a dense distribution of nanoscale Gd2O3 second-phase inclusions in the superconducting film. However, we find that the measured vortex profiles are unexpectedly broad, with full-width-half-maxima typically of 6 µm, and exhibit almost no temperature dependence in the range 10–85 K. Since the lateral displacements of pinned vortex cores are not expected to exceed the superconducting layer thickness, this suggests that the observed broadening is caused by the disruption of the circulating supercurrents due to the high density of nanoscale pinning sites. Deviations of our local magnetisation data from an accepted 2D Bean critical state model also indicate that critical state profiles relax quite rapidly by flux creep. Our measurements provide important information about the role second-phase defects play in enhancing the critical current in these tapes and demonstrate the power of magnetic imaging as a complementary tool in the optimisation of vortex pinning phenomena in 2G-HTS tapes

Observing the Suppression of Superconductivity in RbEuFe4As4 by Correlated Magnetic Fluctuations

In this Letter, we describe quantitative magnetic imaging of superconducting vortices in RbEuFe4As4 in order to investigate the unique interplay between the magnetic and superconducting sublattices. Our scanning Hall microscopy data reveal a pronounced suppression of the superfluid density near the magnetic ordering temperature in good qualitative agreement with a recently developed model describing the suppression of superconductivity by correlated magnetic fluctuations. These results indicate a pronounced exchange interaction between the superconducting and magnetic subsystems in RbEuFe4As4, with important implications for future investigations of physical phenomena arising from the interplay between them

Correlations of structural, magnetic, and dielectric properties of undoped and doped CaCu3Ti4O12

The present work reports synthesis, as well as a detailed and careful characterization of structural, magnetic, and dielectric properties of differently tempered undoped and doped CaCu3Ti4O12 (CCTO) ceramics. For this purpose, neutron and x-ray powder diffraction, SQUID measurements, and dielectric spectroscopy have been performed. Mn-, Fe-, and Ni-doped CCTO ceramics were investigated in great detail to document the influence of low-level doping with 3d metals on the antiferromagnetic structure and dielectric properties. In the light of possible magnetoelectric coupling in these doped ceramics, the dielectric measurements were also carried out in external magnetic fields up to 7 T, showing a minor but significant dependence of the dielectric constant on the applied magnetic field. Undoped CCTO is well-known for its colossal dielectric constant in a broad frequency and temperature range. With the present extended characterization of doped as well as undoped CCTO, we want to address the question why doping with only 1% Mn or 0.5% Fe decreases the room-temperature dielectric constant of CCTO by a factor of ~100 with a concomitant reduction of the conductivity, whereas 0.5% Ni doping changes the dielectric properties only slightly. In addition, diffraction experiments and magnetic investigations were undertaken to check for possible correlations of the magnitude of the colossal dielectric constants with structural details or with magnetic properties like the magnetic ordering, the Curie-Weiss temperatures, or the paramagnetic moment. It is revealed, that while the magnetic ordering temperature and the effective moment of all investigated CCTO ceramics are rather similar, there is a dramatic influence of doping and tempering time on the Curie-Weiss constant.Comment: 10 pages, 11 figure

Characterisation of the muon beams for the Muon Ionisation Cooling Experiment

A novel single-particle technique to measure emittance has been developed and used to characterise seventeen different muon beams for the Muon Ionisation Cooling Experiment (MICE). The muon beams, whose mean momenta vary from 171 to 281 MeV/c, have emittances of approximately 1.2–2.3 π mm-rad horizontally and 0.6–1.0 π mm-rad vertically, a horizontal dispersion of 90–190 mm and momentum spreads of about 25 MeV/c. There is reasonable agreement between the measured parameters of the beams and the results of simulations. The beams are found to meet the requirements of MICE