Lost in the Forest of the Establishment Clause: Elk Grove v. Newdow

This article provides and in-depth examination of the Newdow case and High Court\u27s opinion

Lost in the Forest of the Establishment Clause: Elk Grove v. Newdow

This article provides and in-depth examination of the Newdow case and High Court\u27s opinion

Abstinence Only vs. Comprehensive Sex Education: What are the Arguments? What is the Evidence?

Responding to the continuing health threats of HIV, STIs and unplanned pregnancy among young people, the widely respected Institute of Medicine of the National Academy of Sciences recently recommended eliminating congressional, federal, state and local "requirements that public funds be used for abstinence-only education." And surveys consistently show that the public wants schools to deliver strong abstinence messages alongside information about self-protection for young people who find themselves in sexual situations. The vast majority of parents support sex education in the schools, including the provision of information about contraceptive and condom use.Unfortunately, federal policy is grossly out of step with the wishes of most parents and students, as well as the scientific research. Since the early 1980s, Congress has devoted significant resources to abstinence-only programming. Partly as a result of federal policy and funding changes, public schools are increasingly supporting abstinence-only curricula that are less likely to include information about birth control, STD prevention and sexual orientation. The evidence tells us that these trends represent a dangerous disservice to America's younger generation

Gender, race, and intersectionality on the federal appellate bench.

While theoretical justifications predict that a judge’s gender and race may influence judicial decisions, empirical support for these arguments has been mixed. However, recent increases in judicial diversity necessitate a reexamination of these earlier studies. Rather than examining individual judges on a single characteristic, such as gender or race alone, this research note argues that the intersection of individual characteristics may provide an alternative approach for evaluating the effects of diversity on the federal appellate bench. The results of cohort models examining the joint effects of race and gender suggest that minority female judges are more likely to support criminal defendants’ claims when compared to their colleagues on the bench, even after controlling for other important factors. This suggests that our understanding of judicial behaviors may be assisted by the inclusion of how individual characteristics overlap rather than examining those characteristics alone

Intersecting disadvantages: race, gender, and age discrimination among attorneys.

This article explores the impact of race, gender, age, and intersectionality on attorneys’ perceptions of unfair treatment by other lawyers and on satisfaction with their legal careers. Using an original survey of over 2,000 attorneys, ordered logit is utilized to analyze attorneys’ perceptions of disparate treatment based on race, gender, and age and to test whether minority female attorneys face unique barriers within their professional relationships. We find that minority women are more likely than others to perceive unfair treatment based on race, gender, and age. This also contributes to lower career satisfaction for attorneys who are women of color than for other groups. The findings have important implications for understanding attorney relationships and potential barriers for minority groups within a profession’s culture. These obstacles not only impact attorneys, but could also influence attorney choice for citizens and the prospects for a representative judiciary

PASSPORT-seq: A Novel High-Throughput Bioassay to Functionally Test Polymorphisms in Micro-RNA Target Sites

Next-generation sequencing (NGS) studies have identified large numbers of genetic variants that are predicted to alter miRNA-mRNA interactions. We developed a novel high-throughput bioassay, PASSPORT-seq, that can functionally test in parallel 100s of these variants in miRNA binding sites (mirSNPs). The results are highly reproducible across both technical and biological replicates. The utility of the bioassay was demonstrated by testing 100 mirSNPs in HEK293, HepG2, and HeLa cells. The results of several of the variants were validated in all three cell lines using traditional individual luciferase assays. Fifty-five mirSNPs were functional in at least one of three cell lines (FDR ≤ 0.05); 11, 36, and 27 of them were functional in HEK293, HepG2, and HeLa cells, respectively. Only four of the variants were functional in all three cell lines, which demonstrates the cell-type specific effects of mirSNPs and the importance of testing the mirSNPs in multiple cell lines. Using PASSPORT-seq, we functionally tested 111 variants in the 3' UTR of 17 pharmacogenes that are predicted to alter miRNA regulation. Thirty-three of the variants tested were functional in at least one cell line

Studies of Adult and Larval Zebra Mussel Populations in Conesus Lake, NY

The goal of this study was to assess the status of the zebra mussel population (Family Dreissinidae, species Dreissena polymorpha) in Conesus Lake by sampling benthic adults and planktonic larvae during the summer reproductive season. Another invasive dreissinid bivalve, the quagga mussel, D. bugensis, has firmly established itself in some of the larger Finger Lakes, including Seneca and Canandaigua Lake. Therefore a second goal of this study was to determine if quagga mussels had invaded Conesus Lake. In this report we provide data on population numbers and size distribution of adult zebra mussels and describe temporal patterns of larval density and cohort development. Water quality data for are also provided for a deep-water station where larvae were sampled. Our observations indicate that, while populations of adult mussels have declined by about 20% since the year 2000, adult densities and the supply of larvae are still moderately high and the species seems to be well established in Conesus Lake

Diagnosing ENSO and global warming tropical precipitation shifts using surface relative humidity and temperature

This is the final version of the article. Available from American Meteorological Society via the DOI in this recordLarge uncertainty remains in future projections of tropical precipitation change under global warming. A simplified method for diagnosing tropical precipitation change is tested here on present day El Niño-Southern Oscillation (ENSO) precipitation shifts. This method, based on the weak temperature gradient approximation, assumes precipitation is associated with local surface relative humidity (RH) and air temperature (SAT), relative to the tropical mean. Observed and simulated changes in RH and SAT are subsequently used to diagnose changes in precipitation. Present day ENSO precipitation shifts are successfully diagnosed using observations (r = 0:69), and an ensemble of atmosphere-only (0:51 ≤ r ≤ 0:8) and coupled (0:5 ≤ r ≤ 0:87) climate model simulations. RH (r = 0:56) is much more influential than SAT (r = 0:27) in determining ENSO precipitation shifts for observations and climate model simulations over both land and ocean. Using inter-model differences, a significant relationship is demonstrated between method performance over ocean for present day ENSO and projected global warming (r = 0:68). As a caveat, we note that mechanisms leading to ENSO-related precipitation changes are not a direct analogue for global warming-related precipitation changes. The diagnosis method presented here demonstrates plausible mechanisms which relate changes in precipitation, RH and SAT under different climate perturbations. Therefore, uncertainty in future tropical precipitation changes may be linked with uncertainty in future RH and SAT changes.AT was supported by a NERC studentship NE/M009599/1 and CASE funding from the Met Office. FHL was part supported by the UK-China Research and Innovation Partnership Fund through the Met Office Climate Science for Service Partnership (CSSP) China as part of the Newton Fund. RC was supported by the Newton Fund through the Met Office Climate Science for Service Partnership Brazil (CSSP Brazil)