New Vistas for Competitive Employment of Deaf Persons*

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FACTORS INFLUENCING WEST TENNESSEE FARMERS' WILLINGNESS TO PAY FOR A BOLL WEEVIL ERADICATION PROGRAM

Data from a survey were used to evaluate Tennessee farmers' willingness to pay for the boll weevil eradication program. Producer experience, boll weevil control costs, and attitudes about boll weevil damage and insecticide usage after the program were significant explanatory variables and had a positive influence on willingness to pay.Contingent valuation, cotton, regional pest control, pest management groups, Demand and Price Analysis, Resource /Energy Economics and Policy,

Developing a Predictive Metric to Assess School Viability

This article examines a wide range of parish school indicators that can be used to predict long-term viability

The Anticonvulsant Ethosuximide Disrupts Sensory Function to Extend C. elegans Lifespan

Ethosuximide is a medication used to treat seizure disorders in humans, and we previously demonstrated that ethosuximide can delay age-related changes and extend the lifespan of the nematode Caenorhabditis elegans. The mechanism of action of ethosuximide in lifespan extension is unknown, and elucidating how ethosuximide functions is important for defining endogenous processes that influence lifespan and for exploring the potential of ethosuximide as a therapeutic for age-related diseases. To identify genes that mediate the activity of ethosuximide, we conducted a genetic screen and identified mutations in two genes, che-3 and osm-3, that cause resistance to ethosuximide-mediated toxicity. Mutations in che-3 and osm-3 cause defects in overlapping sets of chemosensory neurons, resulting in defective chemosensation and an extended lifespan. These findings suggest that ethosuximide extends lifespan by inhibiting the function of specific chemosensory neurons. This model is supported by the observation that ethosuximide-treated animals displayed numerous phenotypic similarities with mutants that have chemosensory defects, indicating that ethosuximide inhibits chemosensory function. Furthermore, ethosuximide extends lifespan by inhibiting chemosensation, since the long-lived osm-3 mutants were resistant to the lifespan extension caused by ethosuximide. These studies demonstrate a novel mechanism of action for a lifespan-extending drug and indicate that sensory perception has a critical role in controlling lifespan. Sensory perception also influences the lifespan of Drosophila, suggesting that sensory perception has an evolutionarily conserved role in lifespan control. These studies highlight the potential of ethosuximide and related drugs that modulate sensory perception to extend lifespan in diverse animals

Enzymatic Glycosylation of Vancomycin Aglycon: Completion of a Total Synthesis of Vancomycin and N- and C-Terminus Substituent Effects of the Aglycon Substrate

Studies on the further development of the sequential glycosylations of the vancomycin aglycon catalyzed by the glycosyltransferases GtfE and GtfD and the observation of unusual, perhaps unexpected, aglycon substrate substituent effects on the rate and efficiency of the initial glycosylation reaction are reported

Aquaculture Thesaurus: Descriptors Used in the National Aquaculture Information System

The Aquaculture Thesaurus consists of the descriptors used in entering material into the National Aquaculture Information System {NAIS). Terms have been arranged in a format similar to that used in the Thesaurus of Water Resources Terms published by the U. S. Department of the Interior. The National Aquaculture Information System is a NOAA project which provides computer assisted access to a broad range of information on growing marine, brackish and freshwater organisms. It was developed to answer the need for a centralized source of information in the U.S., and anyone with a need for information on aquaculture can use it

Age and Growth of King Mackerel, \u3cem\u3eScomberomorus cavalla\u3c/em\u3e, from the Atlantic Coast of the United States

Whole sagittae from 683 and sectioned sagittae from 773 adult (age\u3e 0 ; 437-1.310 mm FL), and lapilli from 29 larval (2-7 mm SL) and 69 young-of-the-year (79-320 mm FL) king mackerel, were examined. All fish were from waters off the Atlantic coast of the southeastern United States (Cape Canaveral, Florida to Cape Fear. North Carolina). Back-calculated lengths at ages and von Bertalanffy growth equations were calculated from both whole and sectioned sagittae. Ages determined from sectioned sagittae were significantly greater than ages determined from whole sagittae, and the magnitude of the difference increased with age (from sections). Rings on sectioned sagittae are considered to be true annual increments, forming during June-September. There was no clear pattern to ring formation on whole otoliths. The oldest fish examined was age 21. The daily nature of rings on lapilli of age 0 king mackerel was not validated, but if the marks are formed daily they suggest growth rates of approximately 0.47 mm/d for early larvae and 2.9 mm/d for fish 1-3 months of age