11,108 research outputs found
Fundamental (In)Justice: The Deportation of Long-Term Residents from Canada
Under the Immigration Act, permanent residents and illegal immigrants may, for a number of reasons, be deported from Canada for life. Even after residing in this country for many years, immigrants without the formality of citizenship enjoy only a limited right to remain. The author argues that deportation violates an immigrant\u27s right to life, liberty and security of the person under section 7 of the Charter. And where that person has established fundamental connections with Canada, through family relations, education, employment, culture, etc., deportation, moreover, is not in accordance with the principles of fundamental justice. In determining the principles of fundamental justice as they apply to the deportation of immigrants, the common law alone must not be determinative; one must look to a multitude of sources. These would include other provisions of the Charter, the jurisprudence of free and democratic societies, and customary and conventional international law. All of these sources, when considered together, point to an enhanced recognition of a right to remain for long-term residents
Study of the April 20, 2007 CME-Comet Interaction Event with an MHD Model
This study examines the tail disconnection event on April 20, 2007 on comet
2P/Encke, caused by a coronal mass ejection (CME) at a heliocentric distance of
0.34 AU. During their interaction, both the CME and the comet are visible with
high temporal and spatial resolution by the STEREO-A spacecraft. Previously,
only current sheets or shocks have been accepted as possible reasons for comet
tail disconnections, so it is puzzling that the CME caused this event. The MHD
simulation presented in this work reproduces the interaction process and
demonstrates how the CME triggered a tail disconnection in the April 20 event.
It is found that the CME disturbs the comet with a combination of a
sudden rotation of the interplanetary magnetic field (IMF), followed by a
gradual rotation. Such an interpretation applies our understanding
of solar wind-comet interactions to determine the \textit{in situ} IMF
orientation of the CME encountering Encke.Comment: 13 pages, 3 figures, accepted by the ApJ Letter
Maintaining remission in ulcerative colitis – role of once daily extended-release mesalamine
The aminosalicylates (5-ASA; also referred to as mesalamine-based agents) are considered as first-line in the maintenance of remission of mild to moderate ulcerative colitis (UC). Traditionally these agents have required a large pill burden and multiple daily dosing regimens which may account for the low adherence rates, especially in patients in remission. Extended-release mesalamine is the first once daily mesalamine product approved by the Food and Drug Administration for the maintenance of UC remission. This review will examine the pharmacokinetics, dosing, efficacy, and safety data of extended-release mesalamine, and discuss the potential role of improving medication compliance and decreasing costs in UC maintenance
Galaxy Formation In The Reionization Epoch As Hinted By Wide Field Camera 3 Observations Of The Hubble Ultra Deep Field
We present a large sample of candidate galaxies at z~7--10, selected in the
HUDF using the new observations made by the HST/WFC3. Our sample is composed of
20 z-dropouts, 15 Y-dropouts, and 20 J-dropouts. The surface densities of the
z-dropouts are close to what predicted by earlier studies, however, those of
the Y- and J-dropouts are quite unexpected. While no Y- or J-dropouts have been
found at AB < 28.0 mag, their surface densities seem to increase sharply at
fainter levels. While some of these candidates seem to be close to foreground
galaxies and thus could possibly be gravitationally lensed, the overall surface
densities after excluding such cases are still much higher than what would be
expected if the luminosity function does not evolve from z~7 to 10. Motivated
by such steep increases, we tentatively propose a set of Schechter function
parameters to describe the LFs at z~8 and 10. As compared to their counterpart
at z~7, here L* decreases by ~ 6.5x and Phi* increases by 17--90x. Although
such parameters are not yet demanded by the existing observations, they are
allowed and seem to agree with the data better than other alternatives. If
these LFs are still valid beyond our current detection limit, this would imply
a sudden emergence of a large number of low-luminosity galaxies when looking
back in time to z~10, which, while seemingly exotic, would naturally fit in the
picture of the cosmic hydrogen reionization. These early galaxies could easily
account for the ionizing photon budget required by the reionization, and they
would imply that the global star formation rate density might start from a very
high value at z~10, rapidly reach the minimum at z~7, and start to rise again
towards z~6. In this scenario, the majority of the stellar mass that the
universe assembled through the reionization epoch seems still undetected by
current observations at z~6. [Abridged]Comment: accepted for publication in Research in Astronomy and Astrophysic
An evaluation of the relative efficacy of an open airway, an oxygen reservoir and continuous positive airway pressure 5 cmH2O on the non-ventilated lung
Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsThe aim of this study, during one-lung ventilation, was to evaluate if oxygenation could be improved by use of a simple oxygen reservoir or application of 5 cmH2O continuous positive airway pressure (CPAP) to the non-ventilated lung compared with an open airway. Twenty-three patients with lung malignancy, undergoing thoracotomy requiring at least 60 minutes of one-lung ventilation before lung lobe excision, were studied. After routine induction and establishment of one-lung ventilation, the three treatments were applied in turn to the same patient in a sequence selected randomly. The first treatment was repeated as a fourth treatment and these results of the repeated treatment averaged to minimize the effect of slow changes. Arterial oxygenation was measured by an arterial blood gas 15 minutes after the application of each treatment. Twenty patients completed the study. Mean PaO2 (in mmHg) was 210.3 (SD 105.5) in the 'OPEN' treatment, 186.0 (SD 109.2) in the 'RESERVOIR' treatment, and 240.5 (SD 116.0) in the 'CPAP' treatment. This overall difference was not quite significant (P=0.058, paired ANOVA), but comparison of the pairs showed that there was a significant better oxygenation only with the CPAP compared to the reservoir treatments (t=2.52, P=0.021). While the effect on the surgical field was not apparent in most patients, in one patient surgery was impeded during CPAP. Our results show that the use of a reservoir does not give oxygenation better than an open tube, and is less effective than the use of CPAP 5 cmH2O on the non-ventilated lung during one-lung ventilation.J. Slimani, W. J. Russell, C. Jurisevichttp://www.aaic.net.au/Article.asp?D=200404
An atlas of selected calibrated stellar spectra
Five hundred and fifty six stars in the IRAS PSC-2 that are suitable for stellar radiometric standards and are brighter than 1 Jy at 25 microns were identified. In addition, 123 stars that meet all of our criteria for calibration standards, but which lack a luminosity class were identified. An approach to absolute stellar calibration of broadband infrared filters based upon new models of Vega and Sirius due to Kurucz (1992) is presented. A general technique used to assemble continuous wide-band calibrated infrared spectra is described and an absolutely calibrated 1-35 micron spectrum of alpha(Tau) is constructed and the method using new and carefully designed observations is independently validated. The absolute calibration of the IRAS Low Resolution Spectrometer (LRS) database is investigated by comparing the observed spectrum of alpha(Tau) with that assumed in the original LRS calibration scheme. Neglect of the SiO fundamental band in alpha(Tau) has led to the presence of a specious 'emission' feature in all LRS spectra near 8.5 microns, and to an incorrect spectral slope between 8 and 12 microns. Finally, some of the properties of asteroids that effect their utility as calibration objects for the middle and far infrared region are examined. A technique to determine, from IRAS multiwaveband observations, the basic physical parameters needed by various asteroid thermal models that minimize the number of assumptions required is developed
A Twisted Dimer Model for Knots
We develop a dimer model for the Alexander polynomial of a knot. This recovers Kauffman\u27s state sum model for the Alexander polynomial using the language of dimers. By providing some additional structure we are able to extend this model to give a state sum formula for the twisted Alexander polynomial of a knot depending on a representation of the knot group
Semi-Classical Description of Antiproton Capture on Atomic Helium
A semi-classical, many-body atomic model incorporating a momentum-dependent
Heisenberg core to stabilize atomic electrons is used to study antiproton
capture on Helium. Details of the antiproton collisions leading to eventual
capture are presented, including the energy and angular momentum states of
incident antiprotons which result in capture via single or double electron
ionization, i.e. into [He or He], and the
distribution of energy and angular momentum states following the Auger cascade.
These final states are discussed in light of recently reported, anomalously
long-lived antiproton states observed in liquid He.Comment: 15 pages, 9 figures may be obtained from authors, Revte
Drosophila Cdi4 is a p21/p27/p57-like cyclin-dependent kinase inhibitor with specificity for cyclin E complexes.
The eukaryotic cell cycle is controlled by a network of interacting regulatory proteins. We used an interaction mating two-hybrid assay to identify connections within the cell cycle regulatory network in Drosophila. We tested interactions between Drosophila cyclins and a panel of hundreds of previously identified proteins. One of the connections we identified was the interaction between cyclin E and a novel Drosophila protein, Cdi4. Because Cdi4 was originally identified by its ability to interact with a Drosophila cyclin-dependent kinase, the finding that it interacts with cyclin E strengthened the notion that it functions in cell cycle regulation. We show that Cdi4 can inhibit cyclin E function both in a yeast assay and in vitro. In light of these results, our sequence analysis revealed that Cdi4 is a unique member of the p21/p27/p57 family of Cdk inhibitors. Our results demonstrate that interaction mating assays using large informative panels of proteins can aid the analysis of regulatory networks by generating and constraining hypotheses that guide further work
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