The Accelerated Procedure for Electrical Work (TPA)

The accelerated procedure for electrical work [in French: Travaux électriques selon Procédure Accélérée (TPA)] was introduced in October 1996. It allows the contractor to carry out minor electrical installation jobs (about 350 a year) independently. The special features of the TPA are that the number of hours to be worked is limited to 16 and the cost to less than 1000 CHF. This procedure has substantial advantages for both the requesters and ST division. Firstly, the requester benefits from direct contact with the contractor, prompt action and simplified invoicing. In addition, ST division, relieved of ordinary minor work, can concentrate on larger-scale projects and can take advantage of a simplified system of administration. The author sets out the course of the procedure, its advantages and drawbacks, the statistics and the results of a satisfaction questionnaire. This procedure could be adapted and extended to other operations linked to future contracts

Sequence variation in the haemagglutinin-neuraminidase gene of human parainfluenza virus type 3 isolates in the UK

The sequence variation in a 934 base-pair region of the gene encoding the haemagglutinin-neuraminidase of five human parainfluenza virus type 3 (HPIV3) isolates was determined together with that of a prototype UK strain. All of the clinical isolates were from the Manchester area of the UK and were obtained in 1990. 1991 and 1993. The gene segment was amplified by the polymerase chain reaction using HPIVB-specific oligonucleotide primers. The nucleotide homology of the strains was high, around 99% and specific differences in the UK sequences when compared with that of the US prototype strain were identified. In addition, a number of isolate-specific differences were seen. No correlation was detected between the observed nucleotide mutations and the year of isolation, which supports the hypothesis that HPIV3 shows cocirculation of a heterogeneous population of viruses rather than varying with time in a linear fashion. However, the data suggested that geographically-defined genetic lineages of HPIV3 may exist

Results from Commissioning of the Energy Extraction Facilities of the LHC Machine

The risk of damage to the superconducting magnets, bus bars and current leads of the LHC machine in case of a resistive transition (quench) is being minimized by adequate protection. The protection is based on early quench detection, bypassing the quenching magnets by cold diodes, energy density dilution in the quenching magnets using heaters and, eventually, energy extraction. For two hundred and twenty-six LHC circuits (600 A and 13 kA) extraction of the stored magnetic energy to external dump resistors was required. All these systems are now installed in the machine and the final hardware commissioning has been undertaken. After a short description of the topology and definitive features, layouts and parameters of these systems the paper will focus on the results from their successful commissioning and an analysis of the system performance

Cooling process of the LHC energy extraction resistors

The energy stored in all the LHC dipoles, about 11 GJ, can potentially cause severe damage to the magnets, bus bars and current leads. In order to protect the superconducting elements after a resistive transition, the energy is dissipated into dump resistors switched in series with the magnet chains. This paper describes the cooling process of the resistors and explains the choice process for the main components of the cooling equipment

Overview of platooning systems

This paper presents an overview of current projects that deal with vehicle platooning. The platooning concept can be defined as a collection of vehicles that travel close together, actively coordinated in formation. Some expected advantages of platooning include increased fuel and traffic efficiency, safety and driver comfort. There are many variations of the details of the concept such as: the goals of platooning, how it is implemented, mix of vehicles, the requirements on infrastructure, what is automated (longitudinal and lateral control) and to what level. The following projects are presented: SARTRE a European platooning project; PATH a California traffic automation program that includes platooning; GCDC a cooperative driving initiative, and; Energy ITS a Japanese truck platooning project

Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive: II Clinical effects

Objectives: Combined oral contraceptives (COCs) decrease androgen levels, including testosterone (T), which may be associated with sexual dysfunction and mood complaints in some women. We have shown that co-administration of dehydroepiandrosterone (DHEA) to a drospirenone (DRSP) containing COC restored total T levels to baseline and free T levels by 47%. Here we describe the effects on sexual function, mood and quality of life of such an intervention. Study design: This was a randomized, double-blind, placebo-controlled study in 99 healthy COC starters. A COC containing 30 μg ethinylestradiol (EE) and 3 mg DRSP was used for 3 cycles, followed by 6 cycles of the same COC combined with 50 mg/day DHEA or placebo. Subjects completed the Moos Menstrual Distress Questionnaire (MDQ), the McCoy Female Sexuality Questionnaire (MFSQ) and the short form of the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q). Safety and tolerability, including effects on skin were evaluated. Results: The addition of DHEA induced small, but significant improvements compared to placebo in the MDQ score for: Autonomic reactions during the menstrual (- 2.0 vs 0.71; P = 0.05) and the pre-menstrual phase (- 3.1 vs 2.9; P = 0.01); and for Behavior during the inter-menstrual phase (- 1.4 vs 3.6; P = 0.02). A significant difference was found in the MDQ score for arousal during the pre-menstrual phase in favor of placebo (- 5.0 vs 1.0; P = 0.01). There were no statistically significant differences between groups for the MSFQ and Q-LES-Q scores. DHEA co-administration resulted in an acceptable safety profile. DHEA negated the beneficial effect of the COC on acne according to the subjects' self-assessment. Conclusions: Co-administration with DHEA did not result in consistent improvements in sexual function, mood and quality of life indicators in women taking EE/DRSP. Retrospectively, the 50 mg dose of DHEA may be too low for this COC. Implications: A well-balanced judgment of the clinical consequences of normalizing androgens during COC use may require complete normalization of free T