Universities’ social responsibility through the lens of strategic planning: A content analysis

This paper examines the degree of social responsibility integration in Italian public universities’ medium and long-term planning documents. We adopted a qualitative approach, applying the content analysis technique to a selected sample of 20 strategic plans issued by Italian large and mega universities. The coding instrument was developed considering the 17 Sustainable Development Goals (SDGs) contained in the United Nations 2030 Agenda. Therefore, we identified 17 categories and 103 key symbols. The analysis undertaken showed that to date, Italian public universities still pay little attention in their planning documents to objectives regarding the multiple dimensions of Social Responsibility, mainly in relation to environmental issues, a failure detrimental to University Social Responsibility implementation and achievement. However, there is a greater sensitivity to Social Responsibility issues in some universities’ planning documents, therefore also more mature practices can be identified, showing universities that have institutionalized the concept of sustainability in their planning documents

When and why entrepreneurial employees want to quit their job: Exploring two conflicting mechanisms

Past turnover research has posited personality traits as important antecedents to quit intentions. Nevertheless, previous literature has not investigated the relationship between employees’ entrepreneurial tendencies—a constellation of domain specific traits—and turnover. Drawing on dispositional trait theory and attraction‐selection‐attrition theory, we propose engagement and intentions to start a business as mediators of the relationship between entrepreneurial tendencies and quit intentions. We test our predictions in a sample of full‐time employees from the United Kingdom (N = 224). In line with our hypotheses, an inconsistent mediation is found, where both positive and negative links between entrepreneurial tendencies and turnover intentions were mediated by engagement and intentions to start a business respectively. Thus, entrepreneurial employees were more likely to be engaged, but at the same time also more likely to be considering starting their own business, leading to a conflicting relationship to turnover intentions. The current study informs the human resource management literature concerning the motivational mechanisms explaining turnover intentions among entrepreneurial employees. It also provides practical insights with regards to the effective management of this workforce

Investigation into the effect of season on oestrus in gilts over two years of climate adaptation

This study examined the changes in age at first oestrus, the weaning-to-oestrus interval (WEI), and duration of oestrus (DE) in a Yorkshire sow population during two years of adaptation from a northern (55°48′N, 9°13′W) European region to a southern (44°03′N, 23°35′W) one. The adaptation process induced a grouping effect of gilts around the mean age of the onset of puberty. Autumn and spring were characterized by the most enhanced gilt grouping effect at 201 to 210 days of age. The same effect was found for oestrus duration, which declined from a 12- to 96-hour range in the first year to an 18- to 90-hour range in the second year. The mean age of first oestrus was 0.8 days significantly lower in the second year compared with the first; the maximal lowering (1.7 days) occurred in the winter season. The WEI decreased significantly from the first to the second year in all four seasons, by a mean annual value of 0.88 days (15.9%). DE increased by 6.5 hours (significantly for all seasons) from the first year to the next. DE showed an ascending evolution from winter to spring and descending from summer to autumn, during each monitored year. Adaptation influences the oestrus in sows. The age to puberty and WEI tended to decrease, while DE tended to increase, with a simultaneous decrease in the variability of these oestrus parameters.Keywords: Age of puberty, climate conditions, length of oestrus, weaning to oestrus interva

Direct-write electron-beam lithography of an IR antenna-coupled microbolometer onto the surface of a hemispherical lens

This article describes a method for performing direct-write lithography of an IR antenna-coupled microbolometer onto the surface of a hemispherical lens. Antennas on a dielectric half-space receive power more efficiently from the substrate side than from the air side. The use of a hemispherical lens facilitates reception through the substrate as well as elimination of trapped surface waves that would normally occur in the substrate. Using direct-write lithography onto the surface of the hemispherical lens eliminates the potential of an air gap between the antenna and lens. Additionally, the accuracy of alignment between the antenna and the center of the lens is controlled at the lithographic step. As a result, there is increased responsivity is observed in the antenna-coupled microbolometer when illuminated from the substrate-side compared to air-side illumination. (c) 2006 American Vacuum Society

Comparison of different definitions to classify remission and sustained remission: 1 year TEMPO results

To assess methods to calculate achieving and sustaining remission in a double blind randomised trial in patients with RA who received etanercept, methotrexate, or an etanercept/methotrexate combination. Remission was defined as DAS <1.6, DAS28 <2.6, and ACR70 response. Sustaining remission was analysed in three ways: (a) analysis of sustained DAS remission, DAS28 remission, or ACR70 response continuously for 6 months; (b) analysis of sustained remission appraised through a continuity rewarded scoring system, which is the weighted sum of all intervals in the study in which patients are in DAS or DAS28 remission; or (c) longitudinal modelling of remission odds using generalised estimating equations. Significantly more patients treated with the etanercept/methotrexate combination reached DAS remission (37%) than those treated with either methotrexate (14%) or etanercept (18%) alone (p <0.01). Results for DAS28 and for the ACR70 response were similar. Agreement between DAS remission and DAS28 remission was good, but agreement between either of these and the ACR70 response was less. Patients in DAS or DAS28 remission had a lower level of disease activity (fewer active joints, lower ESR) than those achieving ACR70 response; the converse was seen using pain VAS. The three methods were comparable for sustainability of remission and showed significant advantage for combination therapy, which increased the number and durability of remission periods. DAS and DAS28 remission results were similar for assessing achieving and sustaining remission in RA, frequently differing from patients classified as ACR70 responders. The three methods of examining duration of remission produced comparable result

Dinamica unor indici biochimici în tratamentul litiazei urinare cu Shilintong

Summary Urinary enzymes N-acetil-β-D-glucosam inidase (NAG), Lactate dehydrogenase (LDH), β2-microglobulin (β2-M) levels in blood and urine were measured in the 20 patients with urolithiasis treated with Shilintong and in 26 patients treated using alternate drugs for urolithiasis in association with antibacterial treatment. It was found that the levels of β2-M were high in both the groups before the treatment in com parision to the control group. While it was found that after the treatment the high level of β2-M are present only in first group, this indicates the process of tubular damage. The levels of NAG and LDH were found to remain high in both the groups before and after the treatment this indicates cellular dam age to the tubules indicating the development of pyelonephrites. Shellintong has been found not to be nephrotoxic

Systemic lupus erythematosus – the discrepancy between renal impairment and clinical and immunological manifestations

Systemic lupus erythematosus (SLE) is the prototype of autoimmune diseases with multiorgan involvement, most commonly targeting the skin, joints and kidneys. The existence and type of renal involvement influence the prognosis and this information may be crucial when it comes to establishing the optimal therapy. We present the case of a patient with SLE with skin involvement (vasculitis), joint manifestations and immunological markers remitted under synthetic remissive treatment but with severe renal damage diagnosed at the renal biopsy as a glomerulosclerosis type focal segmental podocytopathy (FSGS) collapsing variant associated with a possible ultrastructural defect of the glomerular basement membrane in the context of the disease with a severe prognosis

Comparative effectiveness of TNF inhibitors and tocilizumab with and without conventional synthetic disease-modifying antirheumatic drugs in a pan-European observational cohort of bio-naive patients with rheumatoid arthritis

Objectives To compare treatment effectiveness in rheumatoid arthritis (RA) patients naïve to biological disease-modifying antirheumatic drugs (bDMARDs) treated with tocilizumab (TCZ) or TNF-inhibitor (TNFi) with (-combo) or without (-mono) conventional synthetic DMARDs (csDMARDs). Methods Patients with RA across 7 European registries, naïve to bDMARDs who initiated treatment with TCZ or TNFi from 2009 to 2016 were included. Drug retention rate was analyzed using Kaplan–Meier and Cox models, and CDAI over time by mixed models. The proportions of patients reaching CDAI low disease activity (LDA) and remission after one year were corrected for attrition. Results 6713 TNFi-combo, 3762 TNFi-mono, 646 TCZ-combo and 384 TCZ-mono were eligible. Crude median retention was 3.67 years (95%CI 3.41-3.83) for TNFi-combo, 4.14 (3.77-4.62) for TNFi-mono, 2.98 (2.76-3.34) for TCZ-combo and 3.63 years (3.34-5.03) for TCZ-mono. After adjustment for covariates, country and year of treatment initiation stratification, hazards of discontinuation were lower for TCZ-mono (0.60, 95% CI 0.52-0.69) and TCZ-combo (0.66, 95% CI 0.54-0.81) compared to TNFi-combo. Adjusted CDAI evolution was not significantly different between groups. CDAI LDA and remission corrected for attrition were similar between TCZ with or without csDMARDs and TNFi-combo. Conclusion In routine care across 7 European countries, the adjusted drug retention, adjusted CDAI over time and attrition-corrected response proportion for RA patients were similar for bio-naïve patients if treated with TNFi-combo, TCZ-combo or TCZ-mono.Peer reviewe