SN 2002lt and GRB 021211: a SN/GRB Connection at z = 1

We present spectroscopic and photometric observations of the afterglow of GRB 021211 and the discovery of its associated supernova, SN 2002lt. The spectrum shows a broad feature (FWHM = 150 A), around 3770 A (in the rest-frame of the GRB), which we interpret as Ca H+K blueshifted by 14400 km/s. Potential sources of contamination due to the host galaxy and/or residuals of telluric absorption have been analyzed and ruled out. Overall, the spectrum shows a suggestive resemblance with the one of the prototypical type-Ic SN 1994I. This might indicate that GRBs are produced also by standard type-Ic supernovae.Comment: 6 pages, 5 color figures. Proceedings of the 2003 GRB Conference (Santa Fe, NM, 2003 Sep 8-12). Needs aipprocs LaTeX clas

The identification of the optical companion to the binary millisecond pulsar J0610-2100 in the Galactic field

We have used deep V and R images acquired at the ESO Very Large Telescope to identify the optical companion to the binary pulsar PSR J0610-2100, one of the black-widow millisecond pulsars recently detected by the Fermi Gamma-ray Telescope in the Galactic plane. We found a faint star (V~26.7) nearly coincident (\delta r ~0".28) with the pulsar nominal position. This star is visible only in half of the available images, while it disappears in the deepest ones (those acquired under the best seeing conditions), thus indicating that it is variable. Although our observations do not sample the entire orbital period (P=0.28 d) of the pulsar, we found that the optical modulation of the variable star nicely correlates with the pulsar orbital period and describes a well defined peak (R~25.6) at \Phi=0.75, suggesting a modulation due to the pulsar heating. We tentatively conclude that the companion to PSR J0610-2100 is a heavily ablated very low mass star (~ 0.02Msun) that completely filled its Roche Lobe.Comment: 17 pages, 5 figures - Accepted for pubblication in Ap

Gaia data release 1: Principles of the photometric calibration of the G band

Context. Gaia is an ESA cornerstone mission launched on 19 December 2013 aiming to obtain the most complete and precise 3D map of our Galaxy by observing more than one billion sources. This paper is part of a series of documents explaining the data processing and its results for Gaia Data Release 1, focussing on the G band photometry. Aims. This paper describes the calibration model of the Gaia photometric passband for Gaia Data Release 1. Methods. The overall principle of splitting the process into internal and external calibrations is outlined. In the internal calibration, a self-consistent photometric system is generated. Then, the external calibration provides the link to the absolute photometric flux scales. Results. The Gaia photometric calibration pipeline explained here was applied to the first data release with good results. Details are given of the various calibration elements including the mathematical formulation of the models used and of the extraction and preparation of the required input parameters (e.g. colour terms). The external calibration in this first release provides the absolute zero point and photometric transformations from the Gaia G passband to other common photometric systems. Conclusions. This paper describes the photometric calibration implemented for the first Gaia data release and the instrumental effects taken into account. For this first release no aperture losses, radiation damage, and other second-order effects have not yet been implemented in the calibration.Comment: 15 pages, 16 figures, Gaia data release 1 documentation special volum

The optical companion to the binary millisecond pulsar J1824-2452H in the globular cluster M28

We report on the optical identification of the companion star to the eclipsing millisecond pulsar PSR J1824-2452H in the galactic globular cluster M28 (NGC 6626). This star is at only 0.2" from the nominal position of the pulsar and it shows optical variability (~ 0.25 mag) that nicely correlates with the pulsar orbital period. It is located on the blue side of the cluster main sequence, ~1.5 mag fainter than the turn-off point. The observed light curve shows two distinct and asymmetric minima, suggesting that the companion star is suffering tidal distortion from the pulsar. This discovery increases the number of non-degenerate MSP companions optically identified so far in globular clusters (4 out of 7), suggesting that these systems could be a common outcome of the pulsar recycling process, at least in dense environments where they can be originated by exchange interactions.Comment: accepted for publication on ApJ, 17 pages, 5 figure

Determinants of Deep Gray Matter Atrophy in Multiple Sclerosis: A Multimodal MRI Study

Deep gray matter involvement is a consistent feature in multiple sclerosis. The aim of this study was to evaluate the relationship between different deep gray matter alterations and the development of subcortical atrophy, as well as to investigate the possible different substrates of volume loss between phenotypes. Seventy-seven patients with MS (52 with relapsing-remitting and 25 with progressive MS) and 41 healthy controls were enrolled in this cross-sectional study. MR imaging investigation included volumetric, DTI, PWI and Quantitative Susceptibility Mapping analyses. Deep gray matter structures were automatically segmented to obtain volumes and mean values for each MR imaging metric in the thalamus, caudate, putamen, and globus pallidus. Between-group differences were probed by ANCOVA analyses, while the contribution of different MR imaging metrics to deep gray matter atrophy was investigated via hierarchic multiple linear regression models. Patients with MS showed a multifaceted involvement of the thalamus and basal ganglia, with significant atrophy of all deep gray matter structures (P.001). In the relapsing-remitting MS group,WMlesion burden proved to be the main contributor to volume loss for all deep gray matter structures (P .006), with a minor role of local microstructural damage, which, in turn, was the main determinant of deep gray matter atrophy in patients with progressive MS (P .01), coupled with thalamic susceptibility changes (P .05). Our study confirms the diffuse involvement of deep gray matter in MS, demonstrating a different behavior between MS phenotypes, with subcortical GM atrophy mainly determined by global WM lesion burden in patients with relapsing-remitting MS, while local microstructural damage and susceptibility changes mainly accounted for the development of deep gray matter volume loss in patients with progressive MS

Evidence for Supernova Signatures in the Spectrum of the Late-time Bump of the Optical Afterglow of GRB 021211

We present photometric and spectroscopic observations of the gamma-ray burst GRB 021211 obtained during the late stages of its afterglow. The light curve shows a rebrightening occurring ~25 days after the GRB. The analysis of a VLT spectrum obtained during the bump (27 days after the GRB) reveals a suggestive resemblance with the spectrum of the prototypical type-Ic SN 1994I, obtained about ~10 days past maximum light. Particularly we have measured a strong, broad absorption feature at 3770 A, which we have identified with Ca II blueshifted by ~14400 km/s, thus indicating that a supernova (SN) component is indeed powering the `bump' in the afterglow decay. Assuming SN 1994I as a template, the spectroscopic and photometric data together indicate that the SN and GRB explosions were at most separated by a few days. Our results suggest that GRBs might be associated also to standard type-Ic supernovae.Comment: 6 pages, 4 color figures. Accepted for publication in A&A Letters. Fig. 4 does not appair in the A&A version due to space restrictions. Includes aa.cls and txfonts.st

redefining the pulvinar sign in fabry disease

BACKGROUND AND PURPOSE: The pulvinar sign refers to exclusive T1WI hyperintensity of the lateral pulvinar. Long considered a common sign of Fabry disease, the pulvinar sign has been reported in many pathologic conditions. The exact incidence of the pulvinar sign has never been tested in representative cohorts of patients with Fabry disease. The aim of this study was to assess the prevalence of the pulvinar sign in Fabry disease by analyzing T1WI in a large Fabry disease cohort, determining whether relaxometry changes could be detected in this region independent of the pulvinar sign positivity. MATERIALS AND METHODS: We retrospectively analyzed brain MR imaging of 133 patients with Fabry disease recruited through specialized care clinics. A subgroup of 26 patients underwent a scan including 2 FLASH sequences for relaxometry that were compared with MRI scans of 34 healthy controls. RESULTS: The pulvinar sign was detected in 4 of 133 patients with Fabry disease (3.0%). These 4 subjects were all adult men (4 of 53, 7.5% of the entire male population) with renal failure and under enzyme replacement therapy. When we tested for discrepancies between Fabry disease and healthy controls in quantitative susceptibility mapping and relaxometry maps, no significant difference emerged for any of the tested variables. CONCLUSIONS: The pulvinar sign has a significantly lower incidence in Fabry disease than previously described. This finding, coupled with a lack of significant differences in quantitative MR imaging, allows hypothesizing that selective involvement of the pulvinar is a rare neuroradiologic sign of Fabry disease

From urn models to zero-range processes: statics and dynamics

The aim of these lecture notes is a description of the statics and dynamics of zero-range processes and related models. After revisiting some conceptual aspects of the subject, emphasis is then put on the study of the class of zero-range processes for which a condensation transition arises.Comment: Lecture notes for the Luxembourg Summer School 200

Classification performance for covid patient prognosis from automatic ai segmentation—a single-center study

Background: COVID assessment can be performed using the recently developed individual risk score (prediction of severe respiratory failure in hospitalized patients with SARS-COV2 infection, PREDI-CO score) based on High Resolution Computed Tomography. In this study, we evaluated the possibility of automatizing this estimation using semi-supervised AI-based Radiomics, leveraging the possibility of performing non-supervised segmentation of ground-glass areas. Methods: We collected 92 from patients treated in the IRCCS Sant’Orsola-Malpighi Policlinic and public databases; each lung was segmented using a pre-trained AI method; ground-glass opacity was identified using a novel, non-supervised approach; radiomic measurements were collected and used to predict clinically relevant scores, with particular focus on mortality and the PREDI-CO score. We compared the prediction obtained through different machine learning approaches. Results: All the methods obtained a well-balanced accuracy (70%) on the PREDI-CO score but did not obtain satisfying results on other clinical characteristics due to unbalance between the classes. Conclusions: Semi-supervised segmentation, implemented using a combination of non-supervised segmentation and feature extraction, seems to be a viable approach for patient stratification and could be leveraged to train more complex models. This would be useful in a high-demand situation similar to the current pandemic to support gold-standard segmentation for AI training

Nonequilibrium Statistical Mechanics of the Zero-Range Process and Related Models

We review recent progress on the zero-range process, a model of interacting particles which hop between the sites of a lattice with rates that depend on the occupancy of the departure site. We discuss several applications which have stimulated interest in the model such as shaken granular gases and network dynamics, also we discuss how the model may be used as a coarse-grained description of driven phase-separating systems. A useful property of the zero-range process is that the steady state has a factorised form. We show how this form enables one to analyse in detail condensation transitions, wherein a finite fraction of particles accumulate at a single site. We review condensation transitions in homogeneous and heterogeneous systems and also summarise recent progress in understanding the dynamics of condensation. We then turn to several generalisations which also, under certain specified conditions, share the property of a factorised steady state. These include several species of particles; hop rates which depend on both the departure and the destination sites; continuous masses; parallel discrete-time updating; non-conservation of particles and sites.Comment: 54 pages, 9 figures, review articl