Social Capital Formation among Turkish Women

The purpose of the current study was to identify Turkish women’s social capital formation. This study consisted of 170 women with low SES residing closer to shantytowns. The authors performed the Logistic regression analysis to examine the social capital formation (civic engagement, trust, social participation, and social networks) of women in terms of six variables (age, educational level, employment and marital status, homeownership, community centers, and the length of stay in the same neighborhood) in four different community centers in Ankara, Turkey. Logistic regression results suggest that the length of stay in the same neighborhood was associated both with staying in touch with neighbors (social networks) and trust in municipal service provision (trust), and women’s educational level was associated with voting (civic engagement) and the utilization of municipal services (social participation). Further research should be conducted by comparing men’s and women’s social capital creation by adding other variables

The role of clinical parameters and diffusion magnetic resonance in preoperative evaluation of leiomyomas

Comparing the role of diffusion-weighted imaging magnetic resonance (DWI-MR) in leiomyomas (LM), which can be in pathologically different variants such as cellular, mitotic active, atypical myoma (bizarre nuclei) and STUMP (smooth muscle tumors of uncertain malignant potential), to clinical findings for determining the malignant potential of myoma. Fifty patients who were diagnosed with myoma uteri between March 2013 and April 2017 and evaluated with DWI-MR in the preoperative period were included in the study. Clinical parameters and DWI-MR evaluations of LMs and atypical LMs were compared. While there was no difference in the clinical parameters between LM and atypical LM, there was a significant difference between abnormalities detected by DWI-MR (diffusion restriction, hypervascularity) (p = 0.012). DWI-MR may be a guide for preoperative leiomyoma evaluation, especially in patients who are planned to sustain fertility. [Med-Science 2020; 9(2.000): 478-81

HUMAN PAPILLOMA VIRUS (HPV) PREVALENCE AND GENOTYPE DISTRIBUTION

Assessment of Human papillomavirus (HPV) prevalence and genotype distribution is important for monitoring the impact of prophylactic HPV vaccination. This study aimed to demonstrate the HPV prevalence and type distribution in women from the Baskent University Adana Dr. Turgut Noyan Practice and Research Center. Cervical specimens from 268 women aged 22-68 years were collected between April 2014 and November 2015. Histopathological examinations were performed for 146 women. HPV DNA was amplified by PCR and HPV and genotyping was undertaken using the Roche (R) linear array detection kit. In total. 124 out of 268eligible samples (46.31%) tested positive for HPV. with the majority of these [84/124 (67.7%1] having high-risk (HR) HPV infection: 20.9% were positive for HPV16 (n=261, and 4% for HPV18 (n=5) HPV type-specific prevalence was 63.9% 53.39 and 80% among cervical intraepithelial neoplasias (CIN) Grades respectively. The coverage of other HR-HPV genotypes apart from 16. included HPV31. 45. 51, 53, and 56 in high-grade cervical lesions. In conclusion, HPV-16 was identified as the main HPV genotype associated with cervical disease in our hospital. The study reports the identification of high-and low-risk HPV genotypes as well as the prevalence of multiple HPV infections

Thermo-physiological comfort properties of various shirt fabrics treated with conventional and nano sized water-oil repellent and wrinkle resistant agents

The extreme temperatures and humidity are quite disturbing climatic conditions and clothing is the only protective material in these cases. During the interactions of the human body, clothing, and the environment, to maintain thermal equilibrium, thermo physiological comfort is crucially important. In general, the thermo physiological comfort features of a fabric include thermal conductivity, thermal flow, thermal absorbtivity, thermal resistance, thickness, water vapor permeability and air permeability. In this study, 21 different kinds of woven shirt fabrics produced from fibers in various blends have been treated with both classical and nano chemicals in four different concentrations to produce fabrics having different water-oil repellent and wrinkle resistant characteristics. The effects of the fiber type, treatment method, chemical type, and chemical concentration on the thermal, water vapor and air permeability properties of the fabrics treated with various finishing processes were investigated by statistical analysis. The results of thermal related properties, air permeability and water vapor permeability of the fabrics confirmed that using cotton, lyocell, and viscose shirt fabrics treated with transfer method could be advantageous, especially in hot climatic regions.Research Foundation of Ege University [2006-MuH-053]The authors acknowledge the Research Foundation of Ege University for the financial support given to this study (Project number: 2006-MuH-053)

Uterine smooth muscle tumor of uncertain malignant potential: fertility and clinical outcomes.

In this study, we aimed to evaluate the clinicopathological features, obstetric, and oncological outcomes of patients diagnosed with a uterine smooth muscle tumors of uncertain malignant potential (STUMP)

Addition of gonadotropin releasing hormone agonist for luteal phase support in in-vitro fertilization: an analysis of 2739 cycles

Objective: Luteal phase is defective in in vitro fertilization (IVF) cycles, and many regimens were tried for the very best luteal phase support (LPS). Gonadotropin releasing hormone (GnRH) agonist use, which was administered as an adjunct to the luteal phase support in IVF cycles, was suggested to improve pregnancy outcome measures in certain randomized studies. We analyzed the effects of addition of GnRH agonist to standard progesterone luteal support on pregnancy outcome measures, particularly the live birth rates. Material and Methods: This is a retrospective cohort study, including 2739 IVF cycles. Long GnRH agonist and antagonist stimulation IVF cycles with cleavage-stage embryo transfer were included. Cycles were divided into two groups: Group A included cycles with single-dose GnRH agonist plus progesterone LPS and Group B included progesterone only LPS. Live birth rates were the primary outcome measures of the analysis. Miscarriage rates and multiple pregnancy rates were the secondary outcome measures. Results: Live birth rates were not statistically different in GnRH agonist plus progesterone (Group A) and progesterone only (Group B) groups in both the long agonist and antagonist stimulation arms (40.8%/41.2% and 32.8%/34.4%, p<0.05 respectively). Moreover, pregnancy rates, implantation rates, and miscarriage rates were found to be similar between groups. Multiple pregnancy rates in antagonist cycles were significantly higher in Group A than those in Group B (12.0% and 6.9%, respectively). Conclusion: A beneficial effect of a single dose of GnRH agonist administration as a luteal phase supporting agent is yet to be determined because of the wide heterogeneity of data present in literature. Well-designed randomized clinical studies are required to clarify any effect of luteal GnRH agonist addition on pregnancy outcome measures with different doses, timing, and administration routes of GnRH agonists

Uterine smooth muscle tumor of uncertain malignant potential: fertility and clinical outcomes

Objective: In this study, we aimed to evaluate the clinicopathological features, obstetric, and oncological outcomes of patients diagnosed with a uterine smooth muscle tumors of uncertain malignant potential (STUMP). Methods: A dual-institutional, database review was carried out to screen patients with STUMP who were treated with upfront surgery between January 2006 and December 2017. Data including age at the time of diagnosis, recurrence rate, disease-free survival, overall survival, and fertility outcomes were retrospectively analyzed. Results: Fifty-seven patients with STUMPs were included in the study. The median age at the time of diagnosis was 42 (range, 16 to 75) years. The median follow-up was 57 (range, 16 to 125) months. Eight patients (14\%) had recurrence during follow-up. Recurrent STUMPs were seen in seven patients and leiomyosarcoma after 14 months in one patient. Seven patients with a recurrent STUMP survived, while the remaining patient died. Recurrence rates were similar for women who underwent myomectomy and those who underwent hysterectomy. The presence of uterine localization of tumor (subserosal vs intramural-submucosal) statistically significantly affected recurrence rates (odds ratio=5.72; 95\% confidence interval=1.349-24.290; p=0.018). Ten of 27 patients who underwent myomectomy for uterine myoma had fertility desire. Seven pregnancies were recorded. Conclusions: Our study results suggest that fertility-sparing approaches are feasible in patients with STUMP, although recurrence may be seen

Recurrence patterns and prognostic factors in lymphovascular space invasion-positive endometrioid endometrial cancer surgically confined to the uterus

Objective: The purpose of this study was to determine the patterns of failure and prognostic factors for lymphovascular space invasion (LVSI)-positive endometrioid endometrial cancer (EC) patients in the setting of negative lymph nodes (LNs). Materials and methods: A multicenter, retrospective department database review was performed to identify LVSI-positive patients with disease surgically confined to the uterus at two gynecologic oncology centers in Turkey. Demographic, clinicopathological and survival data were collected. Results: We identified 185 LVSI-positivewomen with negative LNs during the study period. Fifty-five (29.7%) were classified as Stage IA, 94 (50.8%) as Stage IB, and 36 (19.5%) as Stage II. The median age at diagnosis was 59 years and the median duration of follow-up was 44 months. The total number of the recurrences was 12 (6.5%). We observed 5 (2.9%) loco-regional recurrences, 3 (1.5%) retroperitoneal failures, and 4 (2.0%) distant relapses. The 5-year progression-free survival (PFS) was 86.1% while the 5-year overall survival (OS) rate was 87.7%. Grade 3 histology (Hazard Ratio [HR] 2.9, 95% Confidence Interval [CI] 1.02–8.50; p = 0.04), cervical stromal invasion (HR 4.5, 95% CI 1.61–12.79; p = 0.004) and age ≥ 60 years (HR 5.8, 95% CI 1.62–21.32; p = 0.007) were found to be independent prognostic factors for decreased OS. Adjuvant treatment did not appear as a prognostic factor for OS even in univariate analysis. Conclusion: The recurrence rate among LVSI-positive endometrioid EC patients is low in the setting of negative LNs. However, one out of three patients with a recurrence experiences distant relapses which usually portend worse outcomes. Keywords: Endometrioid adenocarcinoma, Endometrial cancer, Recurrence, Lymphovascular space invasion, Negative lymph node