39 research outputs found
Variety of Methodological Approach in Economics
It has been argued by some that the distinction between orthodox economics and heterodox economics does not fit the growing variety in economic theory, unified by a common methodological approach. On the other hand, it remains a central characteristic of heterodox economics that it does not share this methodological approach, but rather represents a range of alternative methodological approaches. The paper explores the evidence, and arguments, for variety in economics at different levels, and a range of issues which arise. This requires in turn a discussion of the meaning of variety in economics at the different levels of reality, methodology, method and theory. It is concluded that there is scope for more, rather than less, variety in economic methodologies, as well as within methodologies. Further, if variety is not to take the form of “anything goes”, then critical discussion by economists of different approaches to economics, and of variety itself, is required
The Cholecystectomy As A Day Case (CAAD) Score: A Validated Score of Preoperative Predictors of Successful Day-Case Cholecystectomy Using the CholeS Data Set
Background
Day-case surgery is associated with significant patient and cost benefits. However, only 43% of cholecystectomy patients are discharged home the same day. One hypothesis is day-case cholecystectomy rates, defined as patients discharged the same day as their operation, may be improved by better assessment of patients using standard preoperative variables.
Methods
Data were extracted from a prospectively collected data set of cholecystectomy patients from 166 UK and Irish hospitals (CholeS). Cholecystectomies performed as elective procedures were divided into main (75%) and validation (25%) data sets. Preoperative predictors were identified, and a risk score of failed day case was devised using multivariate logistic regression. Receiver operating curve analysis was used to validate the score in the validation data set.
Results
Of the 7426 elective cholecystectomies performed, 49% of these were discharged home the same day. Same-day discharge following cholecystectomy was less likely with older patients (OR 0.18, 95% CI 0.15–0.23), higher ASA scores (OR 0.19, 95% CI 0.15–0.23), complicated cholelithiasis (OR 0.38, 95% CI 0.31 to 0.48), male gender (OR 0.66, 95% CI 0.58–0.74), previous acute gallstone-related admissions (OR 0.54, 95% CI 0.48–0.60) and preoperative endoscopic intervention (OR 0.40, 95% CI 0.34–0.47). The CAAD score was developed using these variables. When applied to the validation subgroup, a CAAD score of ≤5 was associated with 80.8% successful day-case cholecystectomy compared with 19.2% associated with a CAAD score >5 (p < 0.001).
Conclusions
The CAAD score which utilises data readily available from clinic letters and electronic sources can predict same-day discharges following cholecystectomy
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Evaluation of the seismic integrity of a plutonium-handling facility
Many studies have been made by and for the Lawrence Livermore National Laboratory (LLNL) to ensure the seismic safety of its Plutonium Facility (Building 332). These studies have included seismological and geologic field investigations to define the actual seismic hazard existing at the Laboratory site as well as structural studies of the Facility itself. Because the basic seismic design criteria has undergone changes over the years, numerous structural studies and upgrades have been completed. The seismic criteria in use at the LLNL site is reviewed on a continuing basis as new information on the seismicity and geology of the Livermore Valley is obtained. At present, the Laboratory's Earth Sciences Division is conducting a multi-million dollar program to identify and characterize the geologic hazards at the Livermore site, with the primary emphasis on earthquake hazards in the Livermore Valley. This effort is undergoing an independent review by Woodward-Clyde Associates. Additionally, because of increased concerns over the seismic safety of Building 332, the Laboratory has initiated an independent structural review. This review effort will be monitored by the California Seismic Safety Commission to ensure its independence. Both of these studiies are in their early stages and results are not yet available
Seismic analysis of the mirror fusion test facility building
This report describes a seismic analysis of the present Mirror Fusion Test Facility (MFTF) building at the Lawrence Livermore Laboratory. The analysis was conducted to evaluate how the structure would withstand the postulated design-basis earthquake (DBE). We discuss the methods of analysis used and results obtained. Also presented are a detailed description of the building, brief discussions of site geology, seismicity, and soil conditions, the approach used to postulate the DBE, and two methods for incorporating the effects of ductility. Floor spectra for the 2nd, 3rd, and 4th floors developed for preliminary equipment design are also included. The results of the analysis, based on best-estimate equipment loadings, indicate additional bracing and upgrading of connection details are required for the structure to survive the postulated design-basis earthquake. Specific recommendations are made
Natural Phenomena Hazards Modeling Project. Extreme wind/tornado hazard models for Department of Energy sites. Revision 1
Lawrence Livermore National Laboratory (LLNL) has developed seismic and wind hazard models for the Office of Nuclear Safety (ONS), Department of Energy (DOE). The work is part of a three-phase effort aimed at establishing uniform building design criteria for seismic and wind hazards at DOE sites throughout the United States. This report summarizes the final wind/tornado hazard models recommended for each site and the methodology used to develop these models. Final seismic hazard models have been published separately by TERA Corporation. In the final phase, it is anticipated that the DOE will use the hazard models to establish uniform criteria for the design and evaluation of critical facilities. 19 refs., 3 figs., 9 tabs
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Seismic evaluation of commercial plutonium fabrication plants in the United States
This report is an overview of Lawrence Livermore National Laboratory's seismic assessment of six commercial plutonium fabrication plants licensed by the US Nuclear Regulatory Commission (NRC) before September 2, 1971. The seismic assessment generally has three parts: (1) documentation of the structural condition of each facility and its critical equipment; (2) characterization of the seismic hazard (i.e., determination of peak ground acceleration vs return period for each site); and (3) evaluation of seismic capacity to determine ground motion levels at which critical structures and equipment fail. The failure evaluation used structural capacities of median-centered strength characteristics of the as-built configurations from (1) and seismic hazard input from (2). Results of the assessment were partial input for an overall natural risks study by the NRC