12,444 research outputs found
Friction measuring apparatus Patent
Kinetic and static friction force measurement between magnetic tape and magnetic head surface
Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli
Priming and activating immune stimuli have profound effects on macrophages, however, studies generally evaluate stimuli in isolation rather than in combination. In this study we have investigated the effects of pro-inflammatory and anti-inflammatory stimuli either alone or in combination on macrophage metabolism. These stimuli include host factors such as IFNγ and ovalbumin-immunoglobulin immune complexes, or pathogen factors such as LPS. Untargeted LC-MS based metabolomics provided an in-depth profile of the macrophage metabolome, and revealed specific changes in metabolite abundance upon either individual stimuli or combined stimuli. Here, by factoring in an interaction term in the linear model, we define the metabolome interactome. This approach allowed us to determine whether stimuli interact in a synergistic or antagonistic manner. In conclusion this study demonstrates a robust approach to interrogate immune-metabolism, especially systems that model host-pathogen interactions
The Distance of the First Overtone RR Lyrae Variables in the MACHO LMC Database: A New Method to Correct for the Effects of Crowding
Previous studies have indicated that many of the RR Lyrae variables in the
LMC have properties similar to the ones in the Galactic globular cluster M3.
Assuming that the M3 RR Lyrae variables follow the same relationships among
period, temperature, amplitude and Fourier phase parameter phi31 as their LMC
counterparts, we have used the M3 phi31-logP relation to identify the M3-like
unevolved first overtone RR Lyrae variables in 16 fields near the LMC bar. The
temperatures of these variables were calculated from the M3 logP-logTe relation
so that the extinction could be derived for each star separately. Since blended
stars have lower amplitudes for a given period, the period amplitude relation
should be a useful tool for identifying which stars are affected by crowding.
We find that the low amplitude stars are brighter. We remove them from the
sample and derive an LMC distance modulus 18.49+/-0.11.Comment: 30 pages, 7 figures, accepted for publication in the Astronomical
Journa
Fermi-Walker gauge in 2+1 dimensional gravity.
It is shown that the Fermi-Walker gauge allows the general solution of
determining the metric given the sources, in terms of simple quadratures. We
treat the general stationary problem providing explicit solving formulas for
the metric and explicit support conditions for the energy momentum tensor. The
same type of solution is obtained for the time dependent problem with circular
symmetry. In both cases the solutions are classified in terms of the invariants
of the Wilson loops outside the sources. The Fermi-Walker gauge, due to its
physical nature, allows to exploit the weak energy condition and in this
connection it is proved that, both for open and closed universes with
rotational invariance, the energy condition imply the total absence of closed
time like curves. The extension of this theorem to the general stationary
problem, in absence of rotational symmetry is considered. At present such
extension is subject to some assumptions on the behavior of the determinant of
the dreibein in this gauge. PACS number: 0420Comment: 28 pages, RevTex, no figure
Extracting the depolarization coefficient D_NN from data measured with a full acceptance detector
The spin transfer from vertically polarized beam protons to Lambda or Sigma
hyperons of the associated strangeness production pp -> pK Lambda (Sigma) is
described with the depolarization coefficient D_NN. As the polarization of the
hyperons is determined by their weak decays, detectors, which have a large
acceptance for the decay particles, are needed. In this paper a formula is
derived, which describes the depolarization coefficient D_NN by count rates of
a 4 pi detector. It is shown, that formulas, which are given in publications
for detectors with restricted acceptance, are specific cases of this formula
for a 4 pi detector.Comment: Accepted for publication by Nuclear Instruments and Methods in
Physics Research Section
Mesoscopic order and the dimentionality of long-range resonance energy transfer in supramolecular semiconductors
We present time-resolved photoluminescence measurements on two series of
oligo-p-phenylenevinylene materials that self-assemble into supramolecular
nanostructures with thermotropic reversibility in dodecane. One set of
derivatives form chiral, helical stacks while the second set form less
organised, frustrated stacks. Here we study the effects of supramolecular
organisation on the resonance energy transfer rates. We measure these rates in
nanoassemblies formed with mixed blends of oligomers and compare them with the
rates predicted by Foerster theory. Our results and analysis show that control
of supramolecular order in the nanometre lengthscale has a dominant effect on
the efficiency and dimentionality of resonance energy transfer.Comment: 17 Pages, 5 Figures, Submitted to J. Chem. Phy
Generalized Massive Gravity and Galilean Conformal Algebra in two dimensions
Galilean conformal algebra (GCA) in two dimensions arises as contraction of
two copies of the centrally extended Virasoro algebra ( with ). The central charges of
GCA can be expressed in term of Virasoro central charges. For finite and
non-zero GCA central charges, the Virasoro central charges must behave as
asymmetric form . We propose that, the bulk
description for 2d GCA with asymmetric central charges is given by general
massive gravity (GMG) in three dimensions. It can be seen that, if the
gravitational Chern-Simons coupling behaves as of order
O() or (), the central charges
of GMG have the above dependence. So, in non-relativistic scaling
limit , we calculated GCA parameters and finite
entropy in term of gravity parameters mass and angular momentum of GMG.Comment: 9 page
Issues During the Inversion of Crosshole Radar Data: Can We Have Confidence in the Outcome?
An Investigation of Effects of Reversed-type Longitudinal Steps on Resistance and Spray Characteristics of a Flying-boat Hull
High precision measurement of the associated strangeness production in proton proton interactions
A new high precision measurement of the reaction pp -> pK+Lambda at a beam
momentum of 2.95 GeV/c with more than 200,000 analyzed events allows a detailed
analysis of differential observables and their inter-dependencies. Correlations
of the angular distributions with momenta are examined. The invariant mass
distributions are compared for different regions in the Dalitz plots. The cusp
structure at the N Sigma threshold is described with the Flatt\'e formalism and
its variation in the Dalitz plot is analyzed.Comment: accepted for publication in Eur. Phys. J.
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