19 research outputs found
The Relationship of job satisfaction and performance of employees of selected fast food restaurants along Taft Avenue, Manila
The study focused on the employees of selected fast food restaurants along Taft Avenue. There were 142 employees included in this study. The main objective of the paper was to reveal the relationship between the employee\u27s job satisfaction and job performance. To gather sufficient data, the researchers used survey questionnaires as its research instrument. These were given to the managers and employees of selected fast food restaurants. Each manager was tasked to assess their own employees in terms of job performance using the provided surveys. While for the employees, they assessed themselves through a JDI-type of survey to measure their true sentiments regarding their satisfaction on their job. Through the use of several statistical analysis, it was found that there is a significant and positive relationship between job satisfaction and job performance
Isolated kidney transplantation under lumasiran therapy in primary hyperoxaluria type 1: a report of 5 cases
Association of kidney biopsy findings with short- and medium-term outcomes in children with moderate-to-severe IgA vasculitis nephritis
International audienceAssessing the initial severity of immunoglobulin A vasculitis nephritis (IgAV-N) is important due to its determining effect on kidney management and outcomes. This paper describes a multicentre paediatric cohort of IgAV-N patients and discusses relationships among clinical presentation, histological features, and kidney outcome. We retrospectively studied a cohort of 170 children with biopsy-proven IgAV-N, diagnosed between 2007 and 2017. One-quarter of the cohort (27%) presented with initial nephrotic syndrome (NS). Kidney biopsy revealed International Study of Kidney Disease (ISKDC) grade II or grade III in 83% of cases. Endocapillary proliferation was observed in 73% of patients, and chronic lesions were observed in 25%. Data analysis showed a significant association between NS at onset and endocapillary proliferation and cellular crescents. After a median follow-up of 21 months (IQR 12-39), 30% of patients had persistent proteinuria or decreased eGFR. At the end of follow-up, kidney impairment was more often observed in patients with NS at onset and those with cellular crescents and chronic lesions on initial kidney biopsy.Conclusion: This study highlights the relationship between the clinical and histological presentation of IgAV-N and the factors that affect kidney outcome. The ISKDC classification may be improved by including lesions that are more discriminating for disease severity and prognosis. What is Known: • Nephrotic syndrome (NS) or kidney failure at diagnosis and cellular crescents in more than 50% of the glomeruli are recognized as risk factors for poor kidney outcome in immunoglobulin A vasculitis nephritis (IgAV-N). • The reference histological classification of the International Study of Kidney Disease in Children (ISKDC) is primarily based on the presence and number of affected glomeruli (mesangial proliferation, cellular crescents). The updated Oxford classification, which emphasizes tubular atrophy and interstitial fibrosis, is also used to group pathological features of IgAV-N. Both classifications have limitations. What is New: • Medical treatment should not be postponed in patients with IgAV-N and NS until after biopsy, as NS at diagnosis is associated with initial histological severity and poorer kidney outcome. This proposal needs to be verified in further studies. • Endocapillary proliferation is associated with the initial severity of IgAV-N at diagnosis, while chronic glomerular changes and interstitial fibrosis are associated with poorer short- and medium-term kidney outcomes
Outcome in Children with Iga Vasculitis with Nephritis Treated with Oral Immunosuppressive Treatment in Combination with Steroids
ESSD Commentary on Dysphagia Management During COVID Pandemia
Since the World Health Organization declared the COVID-19 pandemic a Global Public Health Emergency, experts in swallowing are seeking guidance on service delivery and clinical procedures. The European Society for Swallowing Disorders provides considerations to support experts in swallowing disorders in clinical practice. During the COVID-19 pandemic, assessment and treatment of patients with oropharyngeal dysphagia should be provided, while at the same time balancing risk of oropharyngeal complications with that of infection of patients and healthcare professionals involved in their management. Elective, non-urgent assessment may be temporarily postponed and patients are triaged to decide whether dysphagia assessment is necessary; instrumental assessment of swallowing is performed only if processing of the instruments can be guaranteed and clinical assessment has not provided enough diagnostic information for treatment prescription. Assessment and management of oropharyngeal dysphagia is a high-risk situation as it must be considered an aerosol-generating procedure. Personal protective equipment (PPE) should be used. Telepractice is encouraged and compensatory treatments are recommended
ESSD Commentary on Dysphagia Management During COVID Pandemia
Since the World Health Organization declared the COVID-19 pandemic a Global Public Health Emergency, experts in swallowing are seeking guidance on service delivery and clinical procedures. The European Society for Swallowing Disorders provides considerations to support experts in swallowing disorders in clinical practice. During the COVID-19 pandemic, assessment and treatment of patients with oropharyngeal dysphagia should be provided, while at the same time balancing risk of oropharyngeal complications with that of infection of patients and healthcare professionals involved in their management. Elective, non-urgent assessment may be temporarily postponed and patients are triaged to decide whether dysphagia assessment is necessary; instrumental assessment of swallowing is performed only if processing of the instruments can be guaranteed and clinical assessment has not provided enough diagnostic information for treatment prescription. Assessment and management of oropharyngeal dysphagia is a high-risk situation as it must be considered an aerosol-generating procedure. Personal protective equipment (PPE) should be used. Telepractice is encouraged and compensatory treatments are recommended
Pediatr Nephrol
BACKGROUND: IgA vasculitis (IgAV) is the most common vasculitis in children. IgAV long-term prognosis depends on kidney involvement or IgA vasculitis with nephritis (IgAVN). To date, steroid treatment (oral steroids or methylprednisolone pulses) has not proven to be formally efficient. This study aimed to assess the role of steroids on IgAVN outcome. METHODS: All children with IgAVN diagnosed 2000-2019 in 14 French pediatric nephrology units with minimal follow-up of 6 months were retrospectively included. Outcomes of patients treated with steroids were compared with those of a control group of untreated patients matched for age, sex, proteinuria, eGFR, and histological features. The primary endpoint was IgAVN remission defined as urine protein-to-creatinine ratio < 20 mg/mmol without impaired eGFR one year after disease onset. RESULTS: A total of 359 patients with IgAVN were included with a median follow-up time of 249 days (range 43-809). One hundred eight (30%) patients received oral steroids alone, 207 (51%) patients received three methylprednisolone pulses followed by oral steroids, and 44 patients (12.5%) did not receive steroids. Thirty-two children treated with oral steroids alone were compared with 32 matched control patients who did not receive steroids. One year after disease onset, IgAVN remission proportion was not different between these two groups: 62% versus 68%, respectively. Ninety-three children treated with oral steroids alone were compared with 93 matched patients treated with three methylprednisolone pulses followed by oral corticosteroids. IgAVN remission proportion was not different between these two groups: 77% versus 73%, respectively. CONCLUSION: The benefit of oral steroids alone and methylprednisolone pulses could not be established based on this observational study. Randomized controlled trials are thus required to determine the efficacy of steroids in IgAVN. A higher resolution version of the Graphical abstract is available as Supplementary information
Analysis of potential surface coatings in Jezero crater by SuperCam on the Perseverance rover
International audienceThe NASA Perseverance Mars rover has been exploring Jezero crater since February 2021. During that time, several rocks with potential coatings were observed. Rock coatings can record the interactions of rock surfaces with atmosphere, regolith, and water, and are important targets for understanding environmental conditions. The SuperCam instrument uses multiple analytical techniques including Laser-Induced Breakdown Spectroscopy (LIBS), a microphone for obtaining acoustic data from the LIBS shockwave, remote micro-imagery (RMI), visible-near infrared (VISIR), Raman, and luminescence spectroscopy. On sols 75-83, SuperCam analyzed a flat paver rock called Nataani that appeared to have a dusty surface with shiny, dark-toned material underneath and ~cm-sized spots of splotchy coating. An initial 10-point LIBS raster with 30 laser pulses per point indicated a potential systematic change in composition with depth, a known signature of coatings and thin layers. To investigate this further, the team conducted two depth profile LIBS rasters consisting of 5-point LIBS rasters with 150 laser pulses per location to sample deeper into the rock. Two additional locations were analyzed with co-located LIBS, Raman, and VISIR. Acoustics data were also collected during the LIBS depth profile analyses. LIBS chemistry data indicate the surface may be relatively enriched in Mg, Mn, Cr, and possibly H, whereas the interior was relatively enriched in Si, Al, and Sr. Notably, the acoustic data did not show a systematic change in amplitude with depth; this suggests that the surface and interior materials had similar material properties, i.e. hardness, optical, and thermal properties. Raman spectra suggested the presence of amorphous silica but due to SuperCams long optical fiber, which also produces a weak signature of amorphous silica, this feature could not be clearly attributed to Nataani. VISIR spectra exhibit a feature attributable to H2O at 1.9 microns, similar to other targets in Jezero. Due to their larger spot sizes relative to LIBS, the fields of view for both Raman and VISIR may contain some signal from dust and/or uncoated rock. Efforts to better understand these signatures, including collection of additional LIBS and acoustics data on similar martian rocks and terrestrial analogs, are ongoing
Analysis of potential surface coatings in Jezero crater by SuperCam on the Perseverance rover
International audienceThe NASA Perseverance Mars rover has been exploring Jezero crater since February 2021. During that time, several rocks with potential coatings were observed. Rock coatings can record the interactions of rock surfaces with atmosphere, regolith, and water, and are important targets for understanding environmental conditions. The SuperCam instrument uses multiple analytical techniques including Laser-Induced Breakdown Spectroscopy (LIBS), a microphone for obtaining acoustic data from the LIBS shockwave, remote micro-imagery (RMI), visible-near infrared (VISIR), Raman, and luminescence spectroscopy. On sols 75-83, SuperCam analyzed a flat paver rock called Nataani that appeared to have a dusty surface with shiny, dark-toned material underneath and ~cm-sized spots of splotchy coating. An initial 10-point LIBS raster with 30 laser pulses per point indicated a potential systematic change in composition with depth, a known signature of coatings and thin layers. To investigate this further, the team conducted two depth profile LIBS rasters consisting of 5-point LIBS rasters with 150 laser pulses per location to sample deeper into the rock. Two additional locations were analyzed with co-located LIBS, Raman, and VISIR. Acoustics data were also collected during the LIBS depth profile analyses. LIBS chemistry data indicate the surface may be relatively enriched in Mg, Mn, Cr, and possibly H, whereas the interior was relatively enriched in Si, Al, and Sr. Notably, the acoustic data did not show a systematic change in amplitude with depth; this suggests that the surface and interior materials had similar material properties, i.e. hardness, optical, and thermal properties. Raman spectra suggested the presence of amorphous silica but due to SuperCams long optical fiber, which also produces a weak signature of amorphous silica, this feature could not be clearly attributed to Nataani. VISIR spectra exhibit a feature attributable to H2O at 1.9 microns, similar to other targets in Jezero. Due to their larger spot sizes relative to LIBS, the fields of view for both Raman and VISIR may contain some signal from dust and/or uncoated rock. Efforts to better understand these signatures, including collection of additional LIBS and acoustics data on similar martian rocks and terrestrial analogs, are ongoing