Optimal investment with intermediate consumption under no unbounded profit with bounded risk

We consider the problem of optimal investment with intermediate consumption in a general semimartingale model of an incomplete market, with preferences being represented by a utility stochastic field. We show that the key conclusions of the utility maximization theory hold under the assumptions of no unbounded profit with bounded risk (NUPBR) and of the finiteness of both primal and dual value functions.Comment: 10 pages, revised version, to appear in the Applied Probability Journal

Cylindrical thin-shell wormholes and energy conditions

We prove the impossibility of cylindrical thin-shell wormholes supported by matter satisfying the energy conditions everywhere, under reasonable assumptions about the asymptotic behaviour of the - in general different - metrics at each side of the throat. In particular, we reproduce for singular sources previous results corresponding to flat and conical asymptotics, and extend them to a more general asymptotic behaviour. Besides, we establish necessary conditions for the possibility of non exotic cylindrical thin-shell wormholes.Comment: 9 pages; slightly improved version of the article accepted in Int. J. Mod. Phys.

Routes to thermodynamic limit on scale-free networks

We show that there are two classes of finite size effects for dynamic models taking place on a scale-free topology. Some models in finite networks show a behavior that depends only on the system size N. Others present an additional distinct dependence on the upper cutoff k_c of the degree distribution. Since the infinite network limit can be obtained by allowing k_c to diverge with the system size in an arbitrary way, this result implies that there are different routes to the thermodynamic limit in scale-free networks. The contact process (in its mean-field version) belongs to this second class and thus our results clarify the recent discrepancy between theory and simulations with different scaling of k_c reported in the literature.Comment: 5 pages, 3 figures, final versio

Beyond Nuclear Pasta: Phase Transitions and Neutrino Opacity of Non-Traditional Pasta

In this work, we focus on different length scales within the dynamics of nucleons in conditions according to the neutron star crust, with a semiclassical molecular dynamics model, studying isospin symmetric matter at subsaturation densities. While varying the temperature, we find that a solid-liquid phase transition exists, that can be also characterized with a morphology transition. For higher temperatures, above this phase transition, we study the neutrino opacity, and find that in the liquid phase, the scattering of low momenta neutrinos remain high, even though the morphology of the structures differ significatively from those of the traditional nuclear pasta.Comment: 12 pages, 10 figure

Network Evolution Based on Centrality

We study the evolution of networks when the creation and decay of links are based on the position of nodes in the network measured by their centrality. We show that the same network dynamics arises under various centrality measures, and solve analytically the network evolution. During the complete evolution, the network is characterized by nestedness: the neighbourhood of a node is contained in the neighbourhood of the nodes with larger degree. We find a discontinuous transition in the network density between hierarchical and homogeneous networks, depending on the rate of link decay. We also show that this evolution mechanism leads to double power-law degree distributions, with interrelated exponents.Comment: 6 pages, 3 figure

Bottom-Up Modeling of Building Stock Dynamics - Investigating the Effect of Policy and Decisions on the Distribution of Energy and Climate Impacts in Building Stocks over Time

In Europe, residential and commercial buildings are directly and indirectly responsible for approximately 30–40% of the overall energy demand and emitted greenhouse gas (GHG) emissions. A large share of these buildings was erected before minimum energy-efficiency standards were implemented and are therefore not energy- or carbon-efficient. Consequently, buildings offer significant potential in terms of energy efficiency and the reduction of GHG emissions compared to the status quo. To make use of this potential at scale, targeted policy measures and strategies are needed that should be based on a quantitative assessment of the feasibility and impact of these measures.Building stock models (BSMs) have long been used to assess the current and future energy demand and GHG emissions of building stocks. Most common BSMs characterize the building stock through the use of archetype buildings, which are taken to be representative of large segments of the stock. The increasing availability of disaggregated datasets—such as building registries, 3D city models, and energy performance certificates—has given rise to building-specific BSMs focusing on describing the status quo as an input to energy planning, primarily on the urban scale. Owing to the availability of building-level data, BSMs can be extended beyond policy advice and urban planning, to the assessment of large building portfolios. Thus far, the advances made in building-specific BSMs on the urban scale have not been transferred to the national scale, where such datasets are often not available. Moreover, the focus on an increasingly detailed description of the existing stock has left approaches for modeling stock dynamics without much development. Stock dynamics, therefore, are still primarily modeled through exogenously defined retrofit, demolition, and new construction rates. This limits the applicability and reliability of model results, as the influence of economic, environmental, or policy factors on stock development is not considered.This thesis addresses these shortcomings and advances modeling practices in BSMs. The thesis with appended papers provides a methodology for how the modeling of national building stock can be further developed in terms of building stock characterization through synthetic building stocks as well as stock dynamics through the use of agent-based modeling. Furthermore, the thesis extends BSM applications to inform the strategic planning of large building portfolios through the integration of a maintenance and renovation scheduling method to project the future development of building portfolios

Probing Majorana neutrinos in rare K and D, D_s, B, B_c meson decays

We study lepton number violating decays of charged K, D, D_s, B and B_c mesons of the form M^+\to {M'}^-\ell^+\ell^+, induced by the existence of Majorana neutrinos. These processes provide information complementary to neutrinoless double nuclear beta decays, and are sensitive to neutrino masses and lepton mixing. We explore neutrino mass ranges m_N from below 1 eV to several hundred GeV. We find that in many cases the branching ratios are prohibitively small, however in the intermediate range m_\pi < m_N < m_{B_c}, in specific channels and for specific neutrino masses, the branching ratios can be at the reach of high luminosity experiments like those at the LHC-b and future Super flavor-factories, and can provide bounds on the lepton mixing parameters.Comment: 25 page

Alamethicin self-assembling in lipid membranes: concentration dependence from pulsed EPR of spin labels

The antimicrobial action of the peptide antibiotic alamethicin (Alm) is commonly related to peptide self-assembling resulting in the formation of voltage-dependent channels in bacterial membranes, which induces ion permeation. To obtain a deeper insight into the mechanism of channel formation, it is useful to know the dependence of self-assembling on peptide concentration. With this aim, we studied Alm F50/5 spin-labeled analogs in a model 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membrane, for peptide-to-lipid (P/L) ratios varying between 1/1500 and 1/100. Pulsed electron-electron double resonance (PELDOR) spectroscopy reveals that even at the lowest concentration investigated, the Alm molecules assemble into dimers. Moreover, under these conditions, electron spin echo envelope modulation (ESEEM) spectroscopy of D2O-hydrated membranes shows an abrupt change from the in-plane to the trans-membrane orientation of the peptide. Therefore, we hypothesize that dimer formation and peptide reorientation are concurrent processes and represent the initial step of peptide self-assembling. By increasing peptide concentration, higher oligomers are formed. A simple kinetic model of equilibrium among monomers, dimers, and pentamers allows for satisfactorily describing the experimental PELDOR data. The inter-label distances in the oligomers obtained from PELDOR experiments become better resolved with increasing P/L ratio, thus suggesting that the supramolecular organization of the higher-order oligomers becomes more defined

Use of the KlADH4 promoter for ethanol-dependent production of recombinant human serum albumine in Kluyveromyces lactis

KlADH4 is a gene of Kluyveromyces lactis encoding a mitochondrial alcohol dehydrogenase activity which is specifically induced by ethanol. The promoter of this gene was used for the expression of heterologous proteins in K. lactis, a very promising organism which can be used as an alternative host to Saccharomyces cerevisiae due to its good secretory properties. In this paper we report the ethanol-driven expression in K. lactis of the bacterial beta-glucuronidase and of the human serum albumin (HSA) genes under the control of the KlADH4 promoter. In particular, we studied the extracellular production of recombinant HSA (rHSA) with integrative and replicative vectors and obtained a significant increase in the amount of the protein with multicopy vectors, showing that no limitation of KlADH4 trans-acting factors occurred in the cells. By deletion analysis of the promoter, we identified an element (UASE) which is sufficient for the induction of KlADH4 by ethanol and, when inserted in the respective promoters, allows ethanol-dependent activation of other yeast genes, such as PGK and LAC4. We also analyzed the effect of medium composition on cell growth and protein secretion. A clear improvement in the production of the recombinant protein was achieved by shifting from batch cultures (0.3 g/liter) to fed-batch cultures (1 g/liter) with ethanol as the preferred carbon source