Neo-Nazism in West Germany

The oharaoter of right-wing extremism in the Federal Republic has undergone extensive transformations in the seventies. As electoral support for the extreme Right declined, a whole range of new groupings emerged pursuing a militant extra-parliamentary strategy. Essential charaoteristics are an increasing tendency to use violence and a close ideological affinity to the NSDAP. They attract a growing number of young people. The increasing susceptibility of young people to rightist ideologies coincides with an economic recession of which young people especially are the victims. Widespread ignorance about Nazism and the prevalence of anti-democratic political attitudes constitute important contributary factors and point to a considerable potential for right-extremism in the Federal Republic., This potential can be attributed. to the negative effects of much of the material dealing with the NS past, to serious deficiencies in the area of historical-political education in schools and, above all, to the absence of any :real process of "coming to terms with the past" in the postwar period. Neo-Nazism is not completely isolated from other trends in West German society. Rightist elements within the established party system and broad sections of the population hold similar views and attitudes. This similarity, linked with an over-exaggerated concern with a perceived threat from the extreme Left may explain the absence of any concerted effort to deal with nee-Nazi tendencies. The response of the courts exemplifies a widespread tendency to under-estimate the significance of the extreme Right. Opposition to the Right is restricted primarily to those circles which suffered most under the Nazi regime. The analysis suggests that one must reject the simplistic view that at the present time the Right does not constitute a serious threat to West German democracy. The study evaluates the wide range of views to be found in secondary sources on the subject of neo-Nazism and is :intended, to contribute to the ongoing discussion conceming the potential for right-extremism in West Germany

Why do old flies die?

International audienc

MEF2 is an in vivo immune-metabolic switch

Infections disturb metabolic homeostasis in many contexts, but the underlying connections are not completely understood. To address this, we use paired genetic and computational screens in Drosophila to identify transcriptional regulators of immunity and pathology and their associated target genes and physiologies. We show that Mef2 is required in the fat body for anabolic function and the immune response. Using genetic and biochemical approaches, we find that MEF2 is phosphorylated at a conserved site in healthy flies and promotes expression of lipogenic and glycogenic enzymes. Upon infection, this phosphorylation is lost, and the activity of MEF2 changes—MEF2 now associates with the TATA binding protein to bind a distinct TATA box sequence and promote antimicrobial peptide expression. The loss of phosphorylated MEF2 contributes to loss of anabolic enzyme expression in Gram-negative bacterial infection. MEF2 is thus a critical transcriptional switch in the adult fat body between metabolism and immunity

The PHENIX Experiment at RHIC

The physics emphases of the PHENIX collaboration and the design and current status of the PHENIX detector are discussed. The plan of the collaboration for making the most effective use of the available luminosity in the first years of RHIC operation is also presented.Comment: 5 pages, 1 figure. Further details of the PHENIX physics program available at http://www.rhic.bnl.gov/phenix

Engine oil acidity detection using solid state ion selective electrodes

Initial results from oil acidity measurements using thick film electrodes are presented. The results suggest that as the oil degrades, its pH/acidity follows a specific trend. Furthermore, an investigation into the feasibility of detecting changes in oil acidity (i.e. TAN value) using ion selective electrodes fabricated utilising thick film technology is presented. The thick-film (screen printing) technique is a decent means for the mass production of rugged, compact and disposable sensors as many such devices can be printed at the same time making them very cost effective to manufacture. Thick-Film ion selective and reference electrodes were fabricated, calibrated and tested in different oil samples varying its acidity. Ruthenium oxide (RuO2) pH sensitive electrodes were screen printed and were used against silver/silver chloride (Ag/AgCl) reference electrodes as well as a commercial glass Ag/AgCl reference electrode. The potentiometric sets of electrodes were calibrated in pH 4, 7 and 10 buffers in a cyclic manner and the voltage was recorded using a high input impedance voltmete

Translationally invariant calculations of form factors, nucleon densities and momentum distributions for finite nuclei with short-range correlations included

Relying upon our previous treatment of the density matrices for nuclei (in general, nonrelativistic self-bound finite systems) we are studying a combined effect of center-of-mass motion and short-range nucleon-nucleon correlations on the nucleon density and momentum distributions in light nuclei ($^{4}He$ and $^{16}O$). Their intrinsic ground-state wave functions are constructed in the so-called fixed center-of-mass approximation, starting with mean-field Slater determinants modified by some correlator (e.g., after Jastrow or Villars). We develop the formalism based upon the Cartesian or boson representation, in which the coordinate and momentum operators are linear combinations of the creation and annihilation operators for oscillatory quanta in the three different space directions, and get the own "Tassie-Barker" factors for each distribution and point out other model-independent results. After this separation of the center-of-mass motion effects we propose additional analytic means in order to simplify the subsequent calculations (e.g., within the Jastrow approach or the unitary correlation operator method). The charge form factors, densities and momentum distributions of $^{4}He$ and $^{16}O$ evaluated by using the well known cluster expansions are compared with data, our exact (numerical) results and microscopic calculations.Comment: 19 pages, 6 figure

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer

We have previously shown that during pregnancy the E-twenty-six (ETS) transcription factor ELF5 directs the differentiation of mammary progenitor cells toward the estrogen receptor (ER)-negative and milk producing cell lineage, raising the possibility that ELF5 may suppress the estrogen sensitivity of breast cancers. To test this we constructed inducible models of ELF5 expression in ER positive luminal breast cancer cells and interrogated them using transcript profiling and chromatin immunoprecipitation of DNA followed by DNA sequencing (ChIP-Seq). ELF5 suppressed ER and FOXA1 expression and broadly suppressed ER-driven patterns of gene expression including sets of genes distinguishing the luminal molecular subtype. Direct transcriptional targets of ELF5, which included FOXA1, EGFR, and MYC, accurately classified a large cohort of breast cancers into their intrinsic molecular subtypes, predicted ER status with high precision, and defined groups with differential prognosis. Knockdown of ELF5 in basal breast cancer cell lines suppressed basal patterns of gene expression and produced a shift in molecular subtype toward the claudin-low and normal-like groups. Luminal breast cancer cells that acquired resistance to the antiestrogen Tamoxifen showed greatly elevated levels of ELF5 and its transcriptional signature, and became dependent on ELF5 for proliferation, compared to the parental cells. Thus ELF5 provides a key transcriptional determinant of breast cancer molecular subtype by suppression of estrogen sensitivity in luminal breast cancer cells and promotion of basal characteristics in basal breast cancer cells, an action that may be utilised to acquire antiestrogen resistance