Chapter 11- Team-Based Learning Brings Academic Rigor, Collaboration, and Community to Online Learning

In early 2020, instructors were faced with a critical and immediate need to move education online in the face of the COVID-19 pandemic. The decision to discontinue face-to-face classes as a protection from the COVID-19 virus presented several questions and challenges, including the need to quickly develop online classes without adequate time to consider the effectiveness of different strategies. While online learning provides accessible and safe educational opportunities for students sheltering in place as a protection against the COVID-19 pandemic, faculty may question if online education provides the academic rigor, needed competencies, and student learning outcomes they hoped for in traditional campus classes

From Scratch to Launch; Leveraging University of Miami Libraries’ Research Information Management System to Cultivate University-wide Partnerships and Support Faculty Research Dissemination and Impact

Since 2017, the University of Miami Libraries (UML) has engaged with key stakeholders and institutional leaders to adapt and build a centralized, sustainable Research Information Management System (RIMS) helping to curate, manage, and promote institutional research output. This paper details the development and rollout of Esploro by Ex Libris (locally branded Scholarship@Miami), the Institutional Repository (IR), and the RIM system for the University of Miami (UM). The UML Esploro Implementation team leveraged Esploro’s Artificial intelligence and Machine Learning features to train the system to automatically capture and fetch relevant scholarly outputs produced by researchers affiliated with UM. Further, we consider the challenges we faced while developing and planning to go live with Scholarship@Miami (Esploro), particularly the difficulty of keeping the institutional leaders engaged and supportive when development took longer than anticipated. Also, we share how we pivoted to support related university initiatives by facilitating integration into the corpus of curated research data while keep proceeding with collecting scholarly outputs and expanding the researcher profiles in Scholarship@Miami. Earlier this year, the public-facing researcher profiles in Scholarship@Miami went live, and over 160,000 research assets and creative works have been added to more than 4,000 Scholarship@Miami profiles to date. Although Scholarship@Miami is still a work in progress, many faculty have expressed an interest in the system and recognized its potential value to their work. Internally, librarians have utilized and analyzed Scholarship@Miami’s data to support decision-making related to transformative and open-access agreements offered by publishers. Lastly, Scholarship@Miami’s data enables UML to contribute more directly to UM research efforts, allowing librarians to expand their support in tracking and evaluating researchers\u27 output and its impact

Physical behaviors and fundamental movement skills in British and Iranian children: an isotemporal substitution analysis

Although the relationship between fundamental movement skills (FMS) and physical behaviours has been established; differences between countries are scarcely explored. The impact of the whole physical behaviour composition, in relation to FMS, has yet to be investigated in 9‐11y children. The aims were, to investigate the associations of substitution of physical behaviours with FMS score, to compare traditional linear regression and compositional data analysis and compare between England and Iran. Measures included accelerometer‐derived activity (sleep (SL), sedentary behaviour (SB), light physical activity (LPA), and moderate‐to‐vigorous physical activity (MVPA) and FMS, using the TGMD‐2, in 119 children (64 boys) from Iran (mean (±SD) age: 9.8±0.3y; BMI of 18.2 ±3.3kg/m2) and 139 (61 boys) children from England (mean (±SD) age: 9.5±0.6y; BMI of 17.7 ±3.1kg/m2). Isometric log‐ratio multiple linear regression models were used to discern the association between FMS and the mean activity composition, and for new compositions where fixed durations of time were reallocated from one behaviour to another, while the remaining behaviours were unchanged. In physical behaviours as a composition, FMS was significantly associated in both ethnicities. English children responded significantly positively to adding 5 or more minutes LPA at the expense of SB (FMS unit change from 0.05 [0.01,0.09] at 5 min to 0.72 [0.01, 1.34] at 60min). Adding 10 minutes or more of SL, at the expense of SB, was associated with a significant, positive change in FMS in all children. Investigation is needed to understand the composition of SB and its potential influence on FMS development

Photoactivatable genetically encoded calcium indicators for targeted neuronal imaging.

Circuit mapping requires knowledge of both structural and functional connectivity between cells. Although optical tools have been made to assess either the morphology and projections of neurons or their activity and functional connections, few probes integrate this information. We have generated a family of photoactivatable genetically encoded Ca(2+) indicators that combines attributes of high-contrast photolabeling with high-sensitivity Ca(2+) detection in a single-color protein sensor. We demonstrated in cultured neurons and in fruit fly and zebrafish larvae how single cells could be selected out of dense populations for visualization of morphology and high signal-to-noise measurements of activity, synaptic transmission and connectivity. Our design strategy is transferrable to other sensors based on circularly permutated GFP (cpGFP)

Transvenous nonfluoroscopic pacemaker implantation during pregnancy guided by 3-dimensional electroanatomic mapping

Patients with congenital heart disease are at ongoing risk of developing both bradyarrhythmias and tachyarrhythmias decades after surgical repair. Rarely, arrhythmias can be exacerbated during pregnancy and require emergent intervention. Here, we report unique experience with nonfluoroscopic pacemaker implantation during pregnancy. Ionizing radiation, even in low doses, is associated with an increased risk of malignancy, and a fetus may be at particularly increased risk.1, 2 Over the past 2 decades, the use of fluoroscopy in cardiac ablation procedures has become nearly obsolete with the development of 3-dimensional (3D) electroanatomic mapping software such as CARTO (Biosense-Webster, Diamond Bar, CA) and NavX or EnSite (St. Jude Medical, Inc., St. Paul, MN).3 However, certain procedures, such as device implants, still commonly use fluoroscopy in most instances.2 Fluoroscopy use in patients with congenital heart disease is of utmost concern because of cumulative radiation exposure from multiple lifetime catheterization, radiographic and computed tomography imaging, and electrophysiological procedures

An Assessment of the Law School Climate for GLBT Students

Nationwide empirical research has assessed the law school climate for gay, lesbian, bisexual, and transgender (GLBT) students. The research shows that the climate for GBLT students at most law schools in the United States, particularly those in urban areas, has improved. The research also shows, however, that this group still encounters substantial discrimination on law school campuses and in law school class¬rooms. This discrimination may result from overt acts, thoughtlessness, and/or neglect on the part of various actors in law school communities. Whatever the cause, the result is that many GLBT students feel disenfranchised from their broader law school communities. Nowhere is this result more telling than in stories of students who do not feel safe “coming out” on law school campuses and, in particular, in the stories of students who go back into the closet in law school. This article addresses the complex and sometimes sub¬tle discrimination faced by GLBT students, and provides proposals for law schools to address this discrimination

Boundary Work for Sustainable Development: Natural Resource Management at the Consultative Group on International Agricultural Research (CGIAR)

Previous research on the determinants of effectiveness in knowledge systems seeking to support sustainable development has highlighted the importance of “boundary work” through which research communities organize their relations with new science, other sources of knowledge, and the worlds of action and policymaking. A growing body of scholarship postulates specific attributes of boundary work that promote used and useful research. These propositions, however, are largely based on the experience of a few industrialized countries. We report here on an effort to evaluate their relevance for efforts to harness science in support of sustainability in the developing world. We carried out a multicountry comparative analysis of natural resource management programs conducted under the auspices of the Consultative Group on International Agricultural Research. We discovered six distinctive kinds of boundary work contributing to the successes of those programs—a greater variety than has been documented in previous studies. We argue that these different kinds of boundary work can be understood as a dual response to the different uses for which the results of specific research programs are intended, and the different sources of knowledge drawn on by those programs. We show that these distinctive kinds of boundary work require distinctive strategies to organize them effectively. Especially important are arrangements regarding participation of stakeholders, accountability in governance, and the use of “boundary objects.” We conclude that improving the ability of research programs to produce useful knowledge for sustainable development will require both greater and differentiated support for multiple forms of boundary work

Toward a General Theory of Boundary Work: Insights from the CGIAR’s Natural Resource Management Programs

Previous research on the determinants of effectiveness in knowledge systems seeking to support sustainable development has highlighted the importance of “boundary work” through which research communities organize their relations with other fields of science, other sources of knowledge, and the worlds of action and policymaking. A growing body of scholarship postulates specific attributes of boundary work that promote used and useful research. These propositions, however, are largely based on the experience of a few industrialized countries. We report here on an effort to evaluate their relevance for efforts to harness science in support of sustainability in the developing world. We carried out a multi-country comparative analysis of natural resource management programs conducted under the auspices of the Consultative Group on International Agricultural Research (CGIAR). We discovered 6 distinctive kinds of boundary work contributing to successes of the CGIAR programs—a greater variety than has been documented in previous studies. We propose that these different kinds of boundary work can be understood as a dual response to the different uses for which the results of specific research programs are intended, and the different sources of knowledge drawn on by those programs. We show that these distinctive kinds of boundary work require distinctive strategies to organize them effectively. Especially important are arrangements regarding participation of stakeholders, governance, and the use of boundary objects. We conclude that improving the ability of research programs to produce useful knowledge for sustainable development will require both greater and differentiated support for multiple forms of boundary work

Rural men and mental health: their experiences and how they managed

There is a growing awareness that a primary source of information about mental health lies with the consumers. This article reports on a study that interviewed rural men with the aim of exploring their mental health experiences within a rural environment. The results of the interviews are a number of stories of resilience and survival that highlight not only the importance of exploring the individuals' perspective of their issues, but also of acknowledging and drawing on their inner strengths. Rural men face a number of challenges that not only increase the risk of mental illness but also decrease the likelihood of them seeking and/or finding professional support. These men's stories, while different from each other, have a common thread of coping. Despite some support from family and friends participants also acknowledged that seeking out professional support could have made the recovery phase easier. Mental health nurses need to be aware, not only of the barrier to professional support but also of the significant resilience that individuals have and how it can be utilised

RNA-binding protein CPEB1 remodels host and viral RNA landscapes.

Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in widespread alternative splicing (AS), shortening of 3' untranslated regions (3' UTRs) and lengthening of poly(A)-tails in host gene transcripts. We found that the host RNA-binding protein CPEB1 was highly induced after infection, and ectopic expression of CPEB1 in noninfected cells recapitulated infection-related post-transcriptional changes. CPEB1 was also required for poly(A)-tail lengthening of viral RNAs important for productive infection. Strikingly, depletion of CPEB1 reversed infection-related cytopathology and post-transcriptional changes, and decreased productive HCMV titers. Host RNA processing was also altered in herpes simplex virus-2 (HSV-2)-infected cells, thereby indicating that this phenomenon might be a common occurrence during herpesvirus infections. We anticipate that our work may serve as a starting point for therapeutic targeting of host RNA-binding proteins in herpesvirus infections