ECUMENISMO: C’È POSTO PER LE DONNE? ASPETTI DELLA RIFLESSIONE ECUMENICA SULLE DONNE E PER LE DONNE A 70 ANNI DALLA FONDAZIONE DEL CEC

O artigo propõe uma reflexão sobre o que pode e deve ser feito no início do século XXI, no campo ecumênico, para encontrar novas maneiras de favorecer uma presença cada vez mais ativa das mulheres na vida da Igreja.RiassuntoL'articolo propone una riflessione su cosa si possa e si debba fare all’inizio del XXI secolo, in campo ecumenico, per trovare nuove forme con le quali favorire una presenza sempre più attiva delle donne alla vita della Chiesa.AbstracThe article proposes a reflection on what can and should be done at the beginning of the 21st century, in the ecumenical field, to find new ways in which to favor an ever more active presence of women in the life of the Church.Enviado: 20-02-2018 - Aprovado e publicado: 12-201

Benedetto XV, la guerra e le posizioni dei vescovi italiani

The cruelty of the First World War changed many lives, dividing communities, as well as the society as a whole. The intent of Benedict XV was to limit as much as possible the damage of the war. Many bishops were committed to take care of their flocks putting aside patriotic feelings; others were unpopular for their obstinacy and inflexibility, causing a number of problems for the Holy See. Benedict XV had to do with shepherds who were often naive and others who were all-too-clever, at all how- ever, as a true father he counseled prudence and wisdom to each of them for the good of Italy and the good of the Church. The call for peace of this «prophet unheard», can now be completely collected and made fruitful.La crueldad de la Primera Guerra Mundial cambió muchas vidas, dividiendo comunidades y la sociedad entera. Benedicto XV intentó limitar lo más posible el daño de la Guerra. Muchos obispos se encontraron en la obligación de ejercer su tarea pastoral prescindiendo de sentimientos patrióticos; otros, en cambio, fueron impopulares por su obstinación e inflexibilidad, causando así no pocos problemas a la Santa Sede. Benedicto XV tuvo que relacionarse con pastores que muchas veces eran ingenuos y con otros que parecían demasiado listos, pero como verdadero padre aconsejaba prudencia y sabiduría a cada uno para el bien de Italia y de la Iglesia. El llamamiento a la paz por parte de este «profeta no escuchado» puede ser ahora recogido por completo y puede dar sus frutos

The Somatic Genomic Landscape of Glioblastoma

We describe the landscape of somatic genomic alterations based on multi-dimensional and comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify several novel mutated genes as well as complex rearrangements of signature receptors including EGFR and PDGFRA. TERT promoter mutations are shown to correlate with elevated mRNA expression, supporting a role in telomerase reactivation. Correlative analyses confirm that the survival advantage of the proneural subtype is conferred by the G-CIMP phenotype, and MGMT DNA methylation may be a predictive biomarker for treatment response only in classical subtype GBM. Integrative analysis of genomic and proteomic profiles challenges the notion of therapeutic inhibition of a pathway as an alternative to inhibition of the target itself. These data will facilitate the discovery of therapeutic and diagnostic target candidates, the validation of research and clinical observations and the generation of unanticipated hypotheses that can advance our molecular understanding of this lethal cancer

Benedetto XV, la guerra e le posizioni dei vescovi italiani

The cruelty of the First World War changed many lives, dividing communities, as well as the society as a whole. The intent of Benedict XV was to limit as much as possible the damage of the war. Many bishops were committed to take care of their flocks putting aside patriotic feelings; others were unpopular for their obstinacy and inflexibility, causing a number of problems for the Holy See. Benedict XV had to do with shepherds who were often naive and others who were all-too-clever, at all how- ever, as a true father he counseled prudence and wisdom to each of them for the good of Italy and the good of the Church. The call for peace of this «prophet unheard», can now be completely collected and made fruitful.La crueldad de la Primera Guerra Mundial cambió muchas vidas, dividiendo comunidades y la sociedad entera. Benedicto XV intentó limitar lo más posible el daño de la Guerra. Muchos obispos se encontraron en la obligación de ejercer su tarea pastoral prescindiendo de sentimientos patrióticos; otros, en cambio, fueron impopulares por su obstinación e inflexibilidad, causando así no pocos problemas a la Santa Sede. Benedicto XV tuvo que relacionarse con pastores que muchas veces eran ingenuos y con otros que parecían demasiado listos, pero como verdadero padre aconsejaba prudencia y sabiduría a cada uno para el bien de Italia y de la Iglesia. El llamamiento a la paz por parte de este «profeta no escuchado» puede ser ahora recogido por completo y puede dar sus frutos

Assessment of the genetic polymorphism and physiological characterization of indigenous Oenococcus oeni strains isolated from Aglianico del Vulture red wine

The aim of this study was a reliable intra-species discrimination and strain biodiversity in Oenococcus oeni populations of two different Aglianico wineries by molecular, biochemical, and physiological characterization. Pulsed field gel electrophoresis (PFGE) analysis revealed a high polymorphism related to the origin (winery) of strains, while differential display PCR (DD-PCR) allowed a further discrimination of strains from the same winery. Moreover, the heterogeneity of these natural populations was investigated by capillary electrophoresis and enzymatic assays. A variability related to a different surface charge distribution was observed among strains, linked to their origin. Malolactic activity study evidenced strain-specific differences in malic acid degradation, and then, only the presence of L(-)-malic acid in the medium induced the mle gene. This study provided evidences on the importance of intra-species biodiversity ofmalolactic bacterial populations in wine ecosystems, as eachwine possess peculiar winemaking conditions and physical–chemical properties which make specific the bacterial survival and growth. This study highlighted a great biodiversity among O. oeni strains that can be also winery specific. Such biodiversity within a certain winery and winemaking area is important for selecting malolactic starters, and strain-specific trait identification is especially important to match individual strains to specific industrial process

CAPILLARY ELECTROPHORESIS ANALYSIS OF STRESSED Oenococcus oeni

The aim of this work was to study the electrophoretic behaviour of Oenococcus oeni (O. oeni) under the effect of ethanol stress. The bacterial outer surface of O. oeni is rich of ionizable groups so the changes in the charging rates in the optimal and stressed conditions could be evaluated by capillary electrophoresis. As a first attempt, it was necessary to optimize the electrophoretic conditions for the identification and efficient separation of this microorganism by capillary electrophoresis. After this preliminary study, the electropherograms show significant differences between cells stressed by ethanol and cells growth in optimal condition. Interestingly, it was observed a substantial difference in electrophoretic profile among different O. oeni strains. The experimental results confirmed the power of capillary electrophoresis for microbial analysis (characterization and separation of microorganisms) since permitting rapid, easy and highly sensitive microbial analysis at low costs for several biological samples