9,362 research outputs found
The Nullity of Bicyclic Signed Graphs
Let \Gamma be a signed graph and let A(\Gamma) be the adjacency matrix of
\Gamma. The nullity of \Gamma is the multiplicity of eigenvalue zero in the
spectrum of A(\Gamma). In this paper we characterize the signed graphs of order
n with nullity n-2 or n-3, and introduce a graph transformation which preserves
the nullity. As an application we determine the unbalanced bicyclic signed
graphs of order n with nullity n-3 or n-4, and signed bicyclic signed graphs
(including simple bicyclic graphs) of order n with nullity n-5
Angiotensin II directly regulates intestinal epithelial NHE3 in Caco2BBE cells
<p>Abstract</p> <p>Background</p> <p>Angiotensin II (AII) effects on intestinal Na<sup>+ </sup>transport may be multifactorial. To determine if AII might have a direct effect on intestinal epithelial Na<sup>+ </sup>transport, we investigated its actions on Na<sup>+ </sup>transport in human intestinal epithelial Caco2BBE cells.</p> <p>Results</p> <p>AII increased apical (brush border) sodium-hydrogen exchanger (NHE)-3, but not NHE2, activity within one hour. Similarly, only apical membrane NHE3 abundance increased at 1–2 hours without any change in total NHE3 protein abundance. From 4–48 hours, AII stimulated progressively larger increases in apical NHE3 activity and surface abundance, which was associated with increases in NHE3 protein expression. At 4–24 hours, NHE3 mRNA increases over baseline expression, suggesting increased gene transcription. This was supported by AII induced increases in rat NHE3 gene promoter-reporter activity. AII induction of NHE3 was blocked by the AII type I receptor antagonist losartan. Acute changes in AII-induced increases in NHE3 exocytosis were blocked by a phospholipase C inhibitor, an arachidonic acid cytochrome P450 epoxygenase inhibitor, as well as phosphatidylinositol 3 kinase (PI3K) inhibitors and Akt inhibitor, partially blocked by a metalloproteinase inhibitor and an EGF (epidermal growth factor) receptor kinase inhibitor, but not affected by an inhibitor of MEK-1 (MAPKK-1, mitogen activated protein kinase kinase-1).</p> <p>Conclusion</p> <p>We conclude that angiotensin II has a direct role in regulating intestinal fluid and electrolyte absorption which may contribute to its overall effects in regulation systemic volume and blood pressure. AII activates several key signaling pathways that induce acute and chronic changes in NHE3 membrane trafficking and gene transcription.</p
BVRIJK light curves and radial velocity curves for selected Magellanic Cloud Cepheids
We present high precision and well sampled BVRIJK light curves and radial
velocity curves for a sample of five Cepheids in the SMC. In addition we
present radial velocity curves for three Cepheids in the LMC. The low
metallicity (Fe/H ~ -0.7) SMC stars have been selected for use in a
Baade-Wesselink type analysis to constrain the metallicity effect on the
Cepheid Period-Luminosity relation. The stars have periods of around 15 days so
they are similar to the Cepheids observed by the Extragalactic Distance Scale
Key Project on the Hubble Space Telescope. We show that the stars are
representative of the SMC Cepheid population at that period and thus will
provide a good sample for the proposed analysis. The actual Baade-Wesselink
analysis are presented in a companion paper.Comment: Accepted for publication in A&A, 23 pages, 10 figures, data tables
will be made available electronically from the CD
High speed quantum gates with cavity quantum electrodynamics
Cavity quantum electrodynamic schemes for quantum gates are amongst the
earliest quantum computing proposals. Despite continued progress, and the
dramatic recent demonstration of photon blockade, there are still issues with
optimal coupling and gate operation involving high-quality cavities. Here we
show dynamic control techniques that allow scalable cavity-QED based quantum
gates, that use the full bandwidth of the cavities. When applied to quantum
gates, these techniques allow an order of magnitude increase in operating
speed, and two orders of magnitude reduction in cavity Q, over passive
cavity-QED architectures. Our methods exploit Stark shift based Q-switching,
and are ideally suited to solid-state integrated optical approaches to quantum
computing.Comment: 4 pages, 3 figures, minor revision
BRYNTRN: A baryon transport model
The development of an interaction data base and a numerical solution to the transport of baryons through an arbitrary shield material based on a straight ahead approximation of the Boltzmann equation are described. The code is most accurate for continuous energy boundary values, but gives reasonable results for discrete spectra at the boundary using even a relatively coarse energy grid (30 points) and large spatial increments (1 cm in H2O). The resulting computer code is self-contained, efficient and ready to use. The code requires only a very small fraction of the computer resources required for Monte Carlo codes
Active Width at a Slanted Active Boundary in Directed Percolation
The width W of the active region around an active moving wall in a directed
percolation process diverges at the percolation threshold p_c as W \simeq A
\epsilon^{-\nu_\parallel} \ln(\epsilon_0/\epsilon), with \epsilon=p_c-p,
\epsilon_0 a constant, and \nu_\parallel=1.734 the critical exponent of the
characteristic time needed to reach the stationary state \xi_\parallel \sim
\epsilon^{-\nu_\parallel}. The logarithmic factor arises from screening of
statistically independent needle shaped sub clusters in the active region.
Numerical data confirm this scaling behaviour.Comment: 5 pages, 5 figure
Study on Evolvement Complexity in an Artificial Stock Market
An artificial stock market is established based on multi-agent . Each agent
has a limit memory of the history of stock price, and will choose an action
according to his memory and trading strategy. The trading strategy of each
agent evolves ceaselessly as a result of self-teaching mechanism. Simulation
results exhibit that large events are frequent in the fluctuation of the stock
price generated by the present model when compared with a normal process, and
the price returns distribution is L\'{e}vy distribution in the central part
followed by an approximately exponential truncation. In addition, by defining a
variable to gauge the "evolvement complexity" of this system, we have found a
phase cross-over from simple-phase to complex-phase along with the increase of
the number of individuals, which may be a ubiquitous phenomenon in multifarious
real-life systems.Comment: 4 pages and 4 figure
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