Unsteady, Free Surface Flows; Solutions Employing the Lagrangian Description of the Motion

Numerical techniques for the solution of unsteady free surface flows are briefly reviewed and consideration is given to the feasibility of methods involving parametric planes where the position and shape of the free surface are known in advance. A method for inviscid flows which uses the Lagrangian description of the motion is developed. This exploits the flexibility in the choice of Lagrangian reference coordinates and is readily adapted to include terms due to inhomogeneity of the fluid. Numerical results are compared in two cases of irrotational flow of a homogeneous fluid for which Lagrangian linearized solutions can be constructed. Some examples of wave run-up on a beach and a shelf are then computed

Cavity-flow wall effects and correction rules

This paper is intended to evaluate the wall effects in the pure-drag case of plane cavity flow past an arbitrary body held in a closed tunnel, and to establish an accurate correction rule. The three theoretical models in common use, namely, the open-wake, Riabouchinsky and re-entrant-jet models, are employed to provide solutions in the form of some functional equations. From these theoretical solutions several different rules for the correction of wall effects are derived for symmetric wedges. These simple correction rules are found to be accurate, as compared with their corresponding exact numerical solutions, for all wedge angles and for small to moderate 'tunnel-spacing ratio' (the ratio of body frontal width to tunnel spacing). According to these correction rules, conversion of a drag coefficient, measured experimentally in a closed tunnel, to the corresponding unbounded flow case requires only the data of the conventional cavitation number and the tunnel-spacing ratio if based on the open-wake model, though using the Riabouchinsky model it requires an additional measurement of the minimum pressure along the tunnel wall. The numerical results for symmetric wedges show that the wall effects invariably result in a lower drag coefficient than in an unbounded flow at the same cavitation number, and that this percentage drag reduction increases with decreasing wedge angle and/or with decreasing tunnel spacing relative to the body frontal width. This indicates that the wall effects are generally more significant for thinner bodies in cavity flows, and they become exceedingly small for sufficiently blunt bodies. Physical explanations for these remarkable features of cavity-flow wall effects are sought; they are supported by the present experimental investigation of the pressure distribution on the wetted body surface as the flow parameters are varied. It is also found that the theoretical drag coefficient based on the Riabouchinsky model is smaller than that predicted by the open-wake model, all the flow parameters being equal, except when the flow approaches the choked state (with the cavity becoming infinitely long in a closed tunnel), which is the limiting case common to all theoretical models. This difference between the two flow models becomes especially pronounced for smaller wedge angles, shorter cavities, and with tunnel walls farther apart. In order to gauge the degree of accuracy of these theoretical models in approximating the real flows, and to ascertain the validity of the correction rules, a series of definitive experiments was carefully designed to complement the theory, and then carried out in a high-speed water tunnel. The measurements on a series of fully cavitating wedges at zero incidence suggest that, of the theoretical models, that due to Riabouchinsky is superior throughout the range tested. The accuracy of the correction rule based on that model has also been firmly established. Although the experimental investigation has been limited to symmetric wedges only, this correction rule (equations (85), (86) of the text) is expected to possess a general validity, at least for symmetric bodies without too large curvatures, since the geometry of the body profile is only implicitly involved in the correction formula. This experimental study is perhaps one of a very few with the particular objective of scrutinizing various theoretical cavity-flow models

Experimental Verification of Cavity-Flow Wall Effects and Correction Rules

This report is intended as a companion to Report No. E-111A.5, "Wall Efects in Cavity Flows", by Wu, Whitney and Lin. Some simple rules for the correction of wall effect are derived from that theoretical study. Experiments designed to complement the theory and to inspect the validity of the correction rules were then carried out in the high-speed water tunnel of the Hydrodynamics Laboratory, California Institute of Technology. The measurements on a series of fully cavitating wedges at zero angle of attack suggested that of the theoretical models that due to Riabouchinsky is superior. They also confirmed the accuracy of the correction rule derived using that model and based on a measurement of the minimum pressure along the tunnel wall

Implant Treatment in the Predoctoral Clinic: A Retrospective Database Study of 1091 Patients

Purpose: This retrospective study was conducted at the Marquette University School of Dentistry to (1) characterize the implant patient population in a predoctoral clinic, (2) describe the implants inserted, and (3) provide information on implant failures. Materials and Methods: The study cohort included 1091 patients who received 1918 dental implants between 2004 and 2012, and had their implants restored by a crown or a fixed dental prosthesis. Data were collected from patient records, entered in a database, and summarized in tables and figures. Contingency tables were prepared and analyzed by a chi-squared test. The cumulative survival probability of implants was described using a Kaplan-Meier survival curve. Univariate and multivariate frailty Cox regression models for clustered observations were computed to identify factors associated with implant failure. Results: Mean patient age (±1 SD) at implantation was 59.7 ± 15.3 years; 53.9% of patients were females, 73.5% were Caucasians. Noble Biocare was the most frequently used implant brand (65.0%). Most implants had a regular-size diameter (59.3%). More implants were inserted in posterior (79.0%) than in anterior jaw regions. Mandibular posterior was the most frequently restored site (43%); 87.8% of implants were restored using single implant crowns. The overall implant-based cumulative survival rate was 96.4%. The patient-based implant survival rate was 94.6%. Implant failure risk was greater among patients than within patients (p \u3c 0.05). Age (\u3e65 years; hazard ratio [HR] = 3.2, p = 0.02), implant staging (two-stage; HR = 4.0, p \u3c 0.001), and implant diameter (wide; HR = 0.4, p = 0.04) were statistically associated with implant failure. Conclusions: Treatment with dental implants in a supervised predoctoral clinic environment resulted in survival rates similar to published results obtained in private practice or research clinics. Older age and implant staging increased failure risk, while the selection of a wide implant diameter was associated with a lower failure risk

The Ucsd/Keck Damped Lya Abundance Database: A Decade of High Resolution Spectroscopy

We publish the Keck/HIRES and Keck/ESI spectra that we have obtained during the first 10 years of Keck observatory operations. Our full sample includes 42 HIRES spectra and 39 ESI spectra along 65 unique sightlines providing abundance measurements on ~85 damped Lya systems. The normalized data can be downloaded from the journal or from our supporting website: http://www.ucolick.org/~xavier/DLA/. The database includes all of the sightlines that have been included in our papers on the chemical abundances, kinematics, and metallicities of the damped Lya systems. This data has also been used to argue for variations in the fine-structure constant. We present new chemical abundance measurements for 10 damped Lya systems and a summary table of high-resolution metallicity measurements (including values from the literature) for 153 damped Lya systems at z>1.6. We caution, however, that this metallicity sample (and all previous ones) is biased to higher N(HI) values than a random sample.Comment: 55 pages, 11 figures. Accepted to ApJS. See http://www.ucolick.org/~xavier/DLA/ for the dat

Jumlah Bakteri Staphylococcus Aureus Dan Skor California Mastitis Test (CMT) Pada Susu Kambing Peranakan Etawa Akibat Dipping Ekstrak Daun Babadotan (Ageratum Conyzoides L.)

The aim of this research is to determine the effect of teat dipping of Ettawa crossbred goat using babadotan leaves (Ageratum conyzoides Linn.) extract on the number of Staphylococcus aureusin milk. The udder inflammation degree also was determined using California Mastitis Test (CMT). The treatments were post milking teat dipping using antiseptic solutions containing 1%, 3%, and 5% of babadotan leaves extract (T1, T2 and T3, respectively). Milk samples were collected at before treatment (H0) and on the day 3, 6 and 9 day of the treatments (H3, H6 and H9, respectively). Commercially antiseptic povidone iodine was used as positive control (K+). Experimental research design was completely randomized design (CRD) split plot types, with the different extract concentration as the main plot and the day of treatment as subplot. CMT scores was analyzed using Kruskal-Wallis test. The results showed that babadotan leaves extract 5% had the same effectiveness (p>0,05) with povidone iodine to reduce the number of Staphylococcus aureusin milk. All extract concentrations (1%, 3% and 5%) had the same effectiveness (H>c0,05(3)) to decrease the CMT scores by postmilking teat dip treatments for 9 days

Tailoring the surface charge of dextran-based polymer coated SPIONs for modulated stem cell uptake and MRI contrast

Tracking stem cells in vivo using non-invasive techniques is critical to evaluate the efficacy and safety of stem cell therapies. Superparamagnetic iron oxide nanoparticles (SPIONs) enable cells to be tracked using magnetic resonance imaging (MRI), but to obtain detectable signal cells need to be labelled with a sufficient amount of iron oxide. For the majority of SPIONs, this can only be obtained with the use of transfection agents, which can adversely affect cell health. Here, we have synthesised a library of dextran-based polymer coated SPIONs with varying surface charge from −1.5 mV to +18.2 mV via a co-precipitation approach and investigated their ability to be directly internalised by stem cells without the need for transfection agents. The SPIONs were colloidally stable in physiological solutions. The crystalline phase of the particles was confirmed with powder X-ray diffraction and their magnetic properties were characterised using SQUID magnetometry and magnetic resonance. Increased surface charge led to six-fold increase in uptake of particles into stem cells and higher MRI contrast, with negligible change in cell viability. Cell tracking velocimetry was shown to be a more accurate method for predicting MRI contrast of stem cells compared to measuring iron oxide uptake through conventional bulk iron quantification

Positive Health and Health Assets: Re-analysis of Longitudinal Datasets

Most approaches to health over the centuries have focused on the absence of illness. In contrast, we are investigating Positive Health —well-being beyond the mere absence of disease. In this article, we describe our theoretical framework and empirical work to date on Positive Health. Positive Health empirically identifies health assets by determining factors that predict health and illness over and above conventional risk factors. Biological health assets might include, for example, high heart rate variability, high levels of HDL, and cardiorespiratory fitness. Subjective health assets might include positive emotions, life satisfaction, hope, optimism, and a sense of meaning and purpose. Functional health assets might include close friends and family members; a stable marriage; meaningful work; participation in a social community; and the ability to carry out work, family, and social roles

The electronic structure and dynamics of the excited triplet state of octaethylaluminum(III)-porphyrin investigated with advanced EPR methods

The photoexcited triplet state of octaethylaluminum(III)-porphyrin (AlOEP) was investigated by time-resolved Electron Paramagnetic Resonance, Electron Nuclear Double Resonance and Electron Spin Echo Envelope Modulation in an organic glass at 10 and 80 K. This main group element porphyrin is unusual because the metal has a small ionic radius and is six-coordinate with axial covalent and coordination bonds. It is not known whether triplet state dynamics influence its magnetic resonance properties as has been observed for some transition metal porphyrins. Together with density functional theory modelling, the magnetic resonance data of AlOEP allow the temperature dependence of the zero-field splitting (ZFS) parameters, D and E, and the proton AZZ hyperfine coupling (hfc) tensor components of the methine protons, in the zero-field splitting frame to be determined. The results provide evidence that the ZFS, hfc and spin–lattice relaxation are indeed influenced by the presence of a dynamic process that is discussed in terms of Jahn-Teller dynamic effects. Thus, these effects should be taken into account when interpreting EPR data from larger complexes containing AlOEP