606 research outputs found
ANALISIS PENGARUH PELATIHAN DAN MOTIVASI TERHADAP KINERJA KARYAWAN DIVISI SDM PT. OTANO MULTI MESINDO
ANALISIS PENGARUH PELATIHAN DAN MOTIVASI TERHADAP KINERJA KARYAWAN DIVISI SDM PT. OTANO MULTI MESINDO
Evaluation of benthic assemblage structure in the NAFO regulatory area with regard to the protection of VME
This article presents the results from the analysis of data acquired during the NEREIDA survey programme (2009-2010) around the Flemish Cap and the tail of the Grand Banks of Newfoundland (NAFO Regulatory Area). Biological samples were collected using a mega box-core, which were processed for the extraction and identification of benthic macrofauna. A suite of physical samples and environmental measurements was also collected for evaluation. Analyses revealed the presence of benthic assemblages that were indicative of Vulnerable Marine Ecosystems (VME). VME indicative assemblages were present mostly outside of the fishing footprint. A simple habitat suitability model identified areas that are likely to accommodate VME indicative assemblages. Areas with the greatest potential to accommodate VME assemblages closely correspond with areas already managed for the protection of VME, where bottom-contact fishing practices are presently excluded. Such results support the notion that existing bottom-fishery exclusion zones should continue to be enforced for the long-term protection of VME.En prensa2,277
A high-flux source of polarization-entangled photons from a periodically-poled KTP parametric downconverter
We have demonstrated a high-flux source of polarization-entangled photons
using a type-II phase-matched periodically-poled KTP parametric downconverter
in a collinearly propagating configuration. We have observed quantum
interference between the single-beam downconverted photons with a visibility of
99% and a measured coincidence flux of 300/s/mW of pump. The
Clauser-Horne-Shimony-Holt version of Bell's inequality was violated with a
value of 2.711 +/- 0.017.Comment: 7 pages submitted to Physical Review
The Second Sound of SU(2)
Using the AdS/CFT correspondence, we calculate the transport coefficients of
a strongly interacting system with a non-abelian SU(2) global symmetry near a
second order phase transition. From the behavior of the poles in the Green's
functions near the phase transition, we determine analytically the speed of
second sound, the conductivity, and diffusion constants. We discuss
similarities and differences between this and other systems with vector order
parameters such as p-wave superconductors and liquid helium-3.Comment: 31 pages, 2 figures; v2 ref added, typo fixe
Apolipoprotein A–I binding to anionic vesicles and lipopolysaccharides: Role for lysine residues in antimicrobial properties
AbstractHuman apolipoprotein A–I (apoA–I) is a 28kDa protein and a major component of high-density lipoproteins, mediating several essential metabolic functions related to heart disease. In the present study the potential protective role against bacterial pathogens was explored. ApoA–I suppressed bacterial growth of Escherichia coli and Klebsiella pneumoniae. The protein was able to bind lipopolysaccharides and showed a strong preference for bilayer vesicles made of phosphatidylglycerol over phosphatidylcholine. Lysine side chains of apoA–I were acetylated to evaluate the importance of electrostatic forces in the binding interaction with both membrane components. Electrophoresis properties, dot blot analysis, circular dichroism, and fluorescence spectroscopy to probe for changes in protein structure indicated that the acetylated protein displayed a strongly reduced lipopolysaccharide and phosphatidylglycerol binding. A mutant containing only the N-terminal domain of apoA–I also showed a reduced ability to interact with the membrane components, although to a lesser extent. These results indicate the potential for apoA–I to function as an antimicrobial protein and exerts this function through lysine residues
Chelator free gallium-68 radiolabelling of silica coated iron oxide nanorods via surface interactions
The commercial availability of combined magnetic resonance imaging (MRI)/positron emission tomography (PET) scanners for clinical use has increased demand for easily prepared agents which offer signal or contrast in both modalities. Herein we describe a new class of silica coated iron–oxide nanorods (NRs) coated with polyethylene glycol (PEG) and/or a tetraazamacrocyclic chelator (DO3A). Studies of the coated NRs validate their composition and confirm their properties as in vivo T₂ MRI contrast agents. Radiolabelling studies with the positron emitting radioisotope gallium-68 (t1/2 = 68 min) demonstrate that, in the presence of the silica coating, the macrocyclic chelator was not required for preparation of highly stable radiometal-NR constructs. In vivo PET-CT and MR imaging studies show the expected high liver uptake of gallium-68 radiolabelled nanorods with no significant release of gallium-68 metal ions, validating our innovation to provide a novel simple method for labelling of iron oxide NRs with a radiometal in the absence of a chelating unit that can be used for high sensitivity liver imaging
Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.
We used on-line electron capture dissociation (ECD) for the large scale identification and localization of sites of phosphorylation. Each FT-ICR ECD event was paired with a linear ion trap collision-induced dissociation (CID) event, allowing a direct comparison of the relative merits of ECD and CID for phosphopeptide identification and site localization. Linear ion trap CID was shown to be most efficient for phosphopeptide identification, whereas FT-ICR ECD was superior for localization of sites of phosphorylation. The combination of confident CID and ECD identification and confident CID and ECD localization is particularly valuable in cases where a phosphopeptide is identified just once within a phosphoproteomics experiment
Serial haematology results in transfused and non-transfused dogs naturally infected with Babesia rossi
This prospective longitudinal study investigated the progression of haematological
changes in 32 transfused and 54 non-transfused dogs naturally infected with Babesia rossi
over the 1st 6 days following diagnosis and treatment. The effect of patient age on the
results of complete blood counts was determined. Haematology data were analysed at
presentation and at 24 hours, 3 days and 6 days after presentation. Dogs were treated with
diminazene aceturate at diagnosis and a blood transfusion was given if deemed clinically
required. Mildly to moderately regenerative normocytic normochromic anaemia was
observed in all dogs throughout the study period. Transfused dogs more often had an
inflammatory leukogram at presentation and at 24 hours, than dogs that were not transfused.
In dogs with a left shift, a concurrent normal or decreased segmented neutrophil
count was found more commonly than neutrophilia. Severe thrombocytopenia that
resolved within a week was common. Blood transfusion alleviated the anaemia, but had no
significant effect on white blood cell or platelet responses. Blood cell responses were not
significantly influenced by age. In conclusion, the red blood cell and white blood cell
responses were less than expected in dogs with babesiosis, given the degree of anaemia and
inflammation present. The magnitude of thrombocytopenia and rapid return of the
platelet count to normal suggested a possible immune-mediated mechanism for the
thrombocytopenia.Funding was received from the Faculty of
Veterinary Science, University of Pretoria.http://www.journals.co.za/ej/ejour_savet.htm
U(2)-like Flavor Symmetries and Approximate Bimaximal Neutrino Mixing
Models involving a U(2) flavor symmetry, or any of a number of its
non-Abelian discrete subgroups, can explain the observed hierarchy of charged
fermion masses and CKM angles. It is known that a large neutrino mixing angle
connecting second and third generation fields may arise via the seesaw
mechanism in these models, without a fine tuning of parameters. Here we show
that it is possible to obtain approximate bimaximal mixing in a class of models
with U(2)-like Yukawa textures. We find a minimal form for Dirac and Majorana
neutrino mass matrices that leads to two large mixing angles, and show that our
result can quantitatively explain atmospheric neutrino oscillations while
accommodating the favored, large angle MSW solution to the solar neutrino
problem. We demonstrate that these textures can arise in models by presenting a
number of explicit examples.Comment: 20 pages RevTex4, 2 figure
- …