Radon-based Image Reconstruction for MPI using a continuously rotating FFL

Magnetic particle imaging is a relatively new tracer-based medical imaging technique exploiting the non-linear magnetization response of magnetic nanoparticles to changing magnetic fields. If the data are generated by using a field-free line, the sampling geometry resembles the one in computerized tomography. Indeed, for an ideal field-free line rotating only in between measurements it was shown that the signal equation can be written as a convolution with the Radon transform of the particle concentration. In this work, we regard a continuously rotating field-free line and extend the forward operator accordingly. We obtain a similar result for the relation to the Radon data but with two additive terms resulting from the additional time-dependencies in the forward model. We jointly reconstruct particle concentration and corresponding Radon data by means of total variation regularization yielding promising results for synthetic data.Comment: YRM & CSE Workshop on Modeling, Simulation & Optimization of Fluid Dynamic Applications 202

Harpacticoida (Crustacea, Copepoda) across a longitudinal transect of the Vema Fracture Zone and along a depth gradient in the Puerto Rico trench

The aim of this study was the investigation of abundance, composition and biodiversity of benthic deep-sea Harpacticoida (Crustacea, Copepoda) in the Verna Fracture Zone (VFZ) and Puerto Rico trench. The study revealed a clear East-West gradient in total abundance of Harpacticoida with a westward decrease in abundances in the VFZ and significant differences in the community composition in the Eastern (East Verna) and Western Atlantic basin (West Verna) on family and genus level. The Puerto Rico trench and its upper slope did not only differ in abundance, but were distinct with respect to community composition on family and genus level. Thus, the upper slope might be considered as an ecotone, a transition zone where a rapid distinction of species composition occurs. In our study fiarea, 837 adult harpacticoid specimens could be assigned to 16 families and 1 subfamily. The most abundant families found were Ameiridae Boeck, 1865, Pseudotachidiidae Lang, 1936 and Ectinosomatidae Sars, 1903. Genera and species were investigated within selected families (Argestidae Por, 1986, Cletodidae T. Scott, 1905, Canthocamptidae Brady, 1880 and Zosimeidae Seifried, 2003) where 11 genera, and 73 species could be discriminated. Within the selected families, the genera Zosime Boeck, 1873 and Mesocletades Sars, 1909 were dominant. In the study area, a high number of singletons was detected, which might be endemic to the respective region. Furthermore, a low total number of species in the trench was observed which was attributed to frequent disturbances in the dynamic environment of the Puerto Rico trench (e.g. turbidites or seismic activity) and high adaptability of specialists and opportunists to these disturbances

Energy loss of a heavy quark produced in a finite-size quark-gluon plasma

We study the energy loss of an energetic heavy quark produced in a high temperature quark-gluon plasma and travelling a finite distance before emerging in the vacuum. While the retardation time of purely collisional energy loss is found to be of the order of the Debye screening length, we find that the contributions from transition radiation and the Ter-Mikayelian effect do not compensate, leading to a reduction of the zeroth order (in an opacity expansion) energy loss.Comment: QM2006 Proceedings; caption of fig 1 and ref [7] modified in v

Les discours sur l’hérédité et la reproduction

Ernst Haeckel fait partie d’un groupe de biologistes qui, au xixe siècle, ont développé une conception de l’hérédité en réaction à la théorie darwinienne de l’évolution. Déjà dans sa Generelle Morphologie (1866), Haeckel avait élaboré des lois de l’hérédité qu’il continua à discuter dans sa Natürliche Schöpfungsgeschichte (1868) ainsi que dans sa Perigenesis der Plastidule (1876). Cet article analyse l’approche de Haeckel dans le contexte des théories de l’évolution émergentes vers la fin du xixe siècle. On suit ici les différentes pistes de l’approche haeckelienne : des perspectives évolutionnaires s’étendant de Lamarck jusqu’à Darwin ont été mêlées à des concepts de la reproduction et de la croissance et s’enrichirent aussi de nombreuses métaphores culturelles et littéraires.Ernst Haeckel belongs to those 19th century biologists who early tried to develop a biological concept of heredity in response to Darwin’s theory of evolution. Already in his Generelle Morphologie (1866) Haeckel developed laws of inheritance, and he continued to discuss these in his Natürliche Schöpfungsgeschichte (1868) and the Perigenesis der Plastidule (1876). This paper analyzes Haeckel’s approach in the context of newly emerging biological theories on heredity in the late 19th century. It traces different discursive elements in Haeckel’s approach: views on evolution from Lamarck to Darwin were intermingled with concepts of reproduction and growth as well as with a variety of cultural and literary metaphors

Take an Adventure Bite

The Adventure Bites - Cooking with Kids program enhanced nutrition curriculum by including a Life Skill development focus and a family night - to improve youth nutrition behaviors. The data was collected using the WSU 4-H Life Skills pre-post youth evaluations, staff surveys, a parent retrospective pre-post survey, and comparison data from non-program sites. The results support adding Life Skills and family night events into youth nutrition curricula. There are opportunities to improve evaluation and do further testing, to determine what the individual impact of Life Skill development and/or individual impact of having family nights had on changes in youth behaviors regarding nutrition

Energy Loss of a Heavy Quark Produced in a Finite Size Medium

We study the medium-induced energy loss $-\Delta E_0(L_p)$ suffered by a heavy quark produced at initial time in a quark-gluon plasma, and escaping the plasma after travelling the distance $L_p$. The heavy quark is treated classically, and within the same framework $-\Delta E_0(L_p)$ consistently includes: the loss from standard collisional processes, initial bremsstrahlung due to the sudden acceleration of the quark, and transition radiation. The radiative loss {\it induced by rescatterings} $-\Delta E_{rad}(L_p)$ is not included in our study. For a ultrarelativistic heavy quark with momentum p \gsim 10 {\rm GeV}, and for a finite plasma with L_p \lsim 5 {\rm fm}, the loss $-\Delta E_0(L_p)$ is strongly suppressed compared to the stationary collisional contribution $-\Delta E_{coll}(L_p) \propto L_p$. Our results support that $-\Delta E_{rad}$ is the dominant contribution to the heavy quark energy loss (at least for L_p \lsim 5 {\rm fm}), as indeed assumed in most of jet-quenching analyses. However they might raise some question concerning the RHIC data on large $p_{\perp}$ electron spectra.Comment: 18 pages, 3 figures. New version clarified and simplified. A critical discussion added in section 2, and previous sections 3 and 4 have been merged together. Main results are unchange

D,L-Lysine-Acetylsalicylate + Glycine (LASAG) Reduces SARS-CoV-2 Replication and Shows an Additive Effect with Remdesivir

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the coronavirus disease-19 (COVID-19) is still challenging healthcare systems and societies worldwide. While vaccines are available, therapeutic strategies are developing and need to be adapted to each patient. Many clinical approaches focus on the repurposing of approved therapeutics against other diseases. However, the efficacy of these compounds on viral infection or even harmful secondary effects in the context of SARS-CoV-2 infection are sparsely investigated. Similarly, adverse effects of commonly used therapeutics against lifestyle diseases have not been studied in detail. Using mono cell culture systems and a more complex chip model, we investigated the effects of the acetylsalicylic acid (ASA) salt D,L-lysine-acetylsalicylate + glycine (LASAG) on SARS-CoV-2 infection in vitro. ASA is commonly known as Aspirin ® and is one of the most frequently used medications worldwide. Our data indicate an inhibitory effect of LASAG on SARS-CoV-2 replication and SARS-CoV-2-induced expression of pro-inflammatory cytokines and coagulation factors. Remarkably, our data point to an additive effect of the combination of LASAG and the antiviral acting drug remdesivir on SARS-CoV-2 replication in vitro

The role of coffee consumption in breast and ovarian cancer risk: updated meta-analyses

Background: Coffee consumption in relation to female hormone-related cancers has been investigated but metaanalyses regarding breast and ovarian cancer include studies published up to 2012 with inconsistent results for ovarian cancer. Methods: We conducted two updated meta-analyses of studies published up to June 2016 to quantify the association of coffee intake with breast and ovarian cancer risk with random effects models. We used the dataset developed by the International Agency for Research on Cancer Working Group for Monograph 116 meeting (May 2016). We additionally performed a PubMed search in June 2016. Results: Summary relative risks (RRs) (95% confidence intervals (CI)) for the study-specific highest vs. lowest coffee consumption were for breast and ovarian cancer respectively: 0.97 (0.93–1.00, Ι2 5.5%, 40 studies, 76,728 cases) and 1.03 (0.93–1.14, Ι 2 31.9%, 31 studies, 13,111 cases). For decaffeinated coffee the corresponding RRs were: 1.00 (0.93-1.08, I2 32.2%, 13 studies) and 0.83 (0.71-0.96, I2 about 0%, 9 studies). The association of coffee with ovarian cancer risk was higher among publications before (RR=1.37, 1.12–1.69) compared to after 2000 (RR=0.96, 0.86-1.06). Conclusion: Our meta-analyses provide strong, quantitative evidence that coffee consumption is not related to breast cancer risk and appears to be unrelated to ovarian cancer risk